Results 21 to 30 of about 3,887 (197)

Organoselenium Chemistry [PDF]

, 2000
Preface ELECTROPHILIC SELENIUM General Introduction Addition Reactions to Double Bonds Selenocyclizations NUCLEOPHILIC SELENIUM Introduction Properties of Selenols and Selenolates Inorganic Nucleophilic Selenium Reagents Organic Nucleophilic Selenium Reagents SELENIUM COMPOUNDS IN RADICAL REACTIONS Homolytic Substitution at Selenium to Generate Radical
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Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives

Nature Communications, 2021
Ebselen is an organoselenium drug that inhibits the SARS-CoV-2 main protease (Mpro). Here, the authors co-crystallised Mpro with ebselen and an ebselen derivative and observed an enzyme bound organoselenium covalent adduct in the crystal structures ...
Kangsa Amporndanai, Xiaoli Meng, Weijuan Shang, Zhenmig Jin, Michael Rogers, Yao Zhao, Zihe Rao, Zhi-Jie Liu, Haitao Yang, Leike Zhang, Paul M. O’Neill, S. Samar Hasnain   +11 more
doaj   +1 more source

Organoselenium Precursors for Atomic Layer Deposition [PDF]

ACS Omega, 2021
Organoselenium compounds with perspective application as Se precursors for atomic layer deposition have been reviewed. The originally limited portfolio of available Se precursors such as H2Se and diethyl(di)selenide has recently been extended by bis(trialkylsilyl)selenides, bis(trialkylstannyl)selenides, cyclic selenides, and tetrakis(N,N ...
Jaroslav Charvot, Raul Zazpe, Jan M. Macak, Filip Bureš   +3 more
openaire   +5 more sources

Biological Effects of Selenium-Containing Ionic Liquids: Cytotoxicity, Mercury Interaction, and Antiproliferative Activity in Glioblastoma Cells. [PDF]

J Appl Toxicol
ABSTRACT Selenium (Se) is an essential micronutrient that participates in redox regulation and cellular homeostasis. Selenium‐containing ionic liquids (ILsSe) have emerged as hybrid compounds combining the properties of organoselenium molecules with the tunable features of ionic liquids.
Rieder GS, de Souza Prestes A, D'Avila da Silva F, de Vargas Barbosa N, Bastidas Ángel AY, Soares MF, Fernandes CM, Petersen MAO, Silva MM, Scholl JN, Figueiró F, Nogara PA, Orian L, Alberto EE, Ascnher M, de Souza DOG, de Souza DG, da Rocha JBT.   +17 more
europepmc   +2 more sources

Genotoxicity and cytotoxicity potential of organoselenium compounds in human leukocytes in vitro

Saudi Pharmaceutical Journal, 2023
In the current work, cytotoxicity and genotoxicity of different organoselenium compounds were examined using Trypan blue exclusion and alkaline comet assays with silver staining respectively.
Mohammad Ibrahim, Daiane Francine Meinerz, Momin Khan, Abid Ali, Muhammad Idrees Khan, Abdullah F. AlAsmari, Metab Alharbi, Abdulrahman Alshammari, João Batista T. da Rocha, Fawaz Alasmari   +9 more
doaj   +1 more source

Unexpected kinetically controlled organoselenium-based isomaleimide: X-ray structure, hirshfeld surface analysis, 3D energy framework approach, and density functional theory calculation

Frontiers in Chemistry, 2022
Reduction of 4,4′-diselanediyldianiline (1) followed by the reaction with bromo-4-(bromomethyl)benzene afforded the corresponding 4-((4-bromobenzyl)selanyl)aniline (2) in 85% yield.
Saad Shaaban, Saad Shaaban, Hela Ferjani, Hany M. Abd El-Lateef, Hany M. Abd El-Lateef, Mai M. Khalaf, Mai M. Khalaf, Mohamed Gouda, Mohamed Alaasar, Mohamed Alaasar, Tarek A. Yousef, Tarek A. Yousef   +11 more
doaj   +1 more source

Organoselenocyanates Tethered Methyl Anthranilate Hybrids with Promising Anticancer, Antimicrobial, and Antioxidant Activities

Inorganics, 2022
Novel methyl anthranilate-based organoselenocyanate hybrids were developed, and their structures were confirmed by the state-of-the-art spectroscopic techniques.
Batool Al-Abdallah, Yasair S. Al-Faiyz, Saad Shaaban   +2 more
doaj   +1 more source

Recent Advances in the Synthesis and Antioxidant Activity of Low Molecular Mass Organoselenium Molecules

Molecules, 2023
Selenium is an essential trace element in living organisms, and is present in selenoenzymes with antioxidant activity, like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR).
João M. Anghinoni, Paloma T. Birmann, Marcia J. da Rocha, Caroline S. Gomes, Michael J. Davies, César A. Brüning, Lucielli Savegnago, Eder J. Lenardão   +7 more
doaj   +1 more source

Organoselenium-Catalyzed Cross-Dehydrogenative Coupling of Alkenes and Azlactones

, 2022
The carbon–carbon bond-forming cross-dehydrogenative coupling of alkenes and azlactones by organoselenium catalysis involving a high-valent para-methoxyphenyl selenium species is disclosed.
Xiaodan Zhao, Wei Wei, Wei Wei (21173), Xiaodan Zhao (136112)   +3 more
core   +1 more source

Synthesis of 3,4-Bis(Butylselanyl)Selenophenes and 4-Alkoxyselenophenes Promoted by Oxone^®

Molecules, 2021
We describe herein an alternative transition-metal-free procedure to access 3,4-bis(butylselanyl)selenophenes and the so far unprecedented 3-(butylselanyl)-4-alkoxyselenophenes. The protocol involves the 5-endo-dig electrophilic cyclization of 1,3-diynes
Paola S. Hellwig, Jonatan S. Guedes, Angelita M. Barcellos, Gelson Perin, Eder J. Lenardão   +4 more
doaj   +1 more source