Antiviral Effect of 5′-Arylchalcogeno-3-aminothymidine Derivatives in SARS-CoV-2 Infection
Molecules, 2023 The understanding that zidovudine (ZDV or azidothymidine, AZT) inhibits the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 and that chalcogen atoms can increase the bioactivity and reduce the toxicity of AZT has directed our search for the discovery ...
Amanda Resende Tucci +13 more
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Photochemistry of N-(selenoalkyl)-phthalimides. Formation of N, Se-heterocyclic systems [PDF]
, 2015 A variety of N-(selenomethyl)alkyl-phthalimides (alkyl = -(CH2)n-; n = 2-5, 1a, b, d, e) and N-(selenobenzyl)propyl phthalimide (1c) were synthesized and their photochemistry was studied at λ = 300 nm.
Argüello, Juan Elias +3 more
core +1 more source
Synthesis and Antioxidant Properties of Organoselenium Compounds
Current Medicinal Chemistry, 2023 Background: The chemistry of organoselenium reagents provides an asset for organic synthesis. The versatility of these reagents as electrophiles and nucleophiles makes them one of the key components of organic synthesis. Various synthetic transformations such as oxyselenenylations, selenocyclization and selenoxide elimination have been successfully ...
Ritu Mamgain +2 more
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Design, Synthesis, and Biological Evaluation of Novel Hydroxamic Acid-Based Organoselenium Hybrids
Pharmaceuticals, 2023 We report the design and synthesis of novel hydroxamic acid-tethered organoselenium (OSe) hybrids. Their antimicrobial and anticancer activities were assessed against different microbes (e.g., Candida albicans (C. albicans), Escherichia coli (E.
Jameelah S. Alotaibi +2 more
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A new polymorph of phenylselenium trichloride [PDF]
, 2019 A second polymorph of phenylselenium trichloride, PhSeCl3 or C6H5Cl3Se, is disclosed, which is comprised of asymmetric chlorine-bridged noncovalent dimer units rather than polymeric chains.
Bloomfield, Hannah R., Ritch, Jamie S.
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Differential genotoxicity of diphenyl diselenide (PhSe)2 and diphenyl ditelluride (PhTe)2 [PDF]
, 2014 Organoselenium compounds have been pointed out as therapeutic agents. In contrast, the potential therapeutic aspects of tellurides have not yet been demonstrated.
Daiane Francine Meinerz +6 more
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Scientific Reports, 2023 Two organoselenium thiourea derivatives, 1-(4-(methylselanyl)phenyl)-3-phenylthiourea (DS036) and 1-(4-(benzylselanyl)phenyl)-3-phenylthiourea (DS038) were produced and categorized using FTIR and NMR (1H and 13C).
Hany M. Abd El-Lateef +7 more
doaj +1 more source
A Computational Study of 2-Selenobarbituric Acid: Conformational Analysis, Enthalpy of Formation, Acidity and Basicity. [PDF]
, 2016 Peer ...
Notario, Rafael
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Flavoprotein monooxygenases for oxidative biocatalysis: recombinant expression in microbial hosts and applications [PDF]
, 2014 External flavoprotein monooxygenases comprise a group of flavin-dependent oxidoreductases that catalyze the insertion of one atom of molecular oxygen into an organic substrate and the second atom is reduced to water. These enzymes are involved in a great
Bianchi, Dario Alejandro +2 more
core +2 more sources
“Green Is the Color”: An Update on Ecofriendly Aspects of Organoselenium Chemistry
Molecules, 2022 Organoselenium compounds have been successfully applied in biological, medicinal and material sciences, as well as a powerful tool for modern organic synthesis, attracting the attention of the scientific community. This great success is mainly due to the
Juliano B. Azeredo +6 more
doaj +1 more source