Results 21 to 30 of about 2,820 (183)
Inorganics, 2023 Oxidative stress is the cause of various pathologies and disorders of cellular functions. Substances that reduce the pathological effect of oxidative stress on homeostasis include organoselenium compounds of natural and synthetic origin. Depending on the
Maxim V. Musalov +6 more
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The effects of synthetic organoselenium compounds on nitric oxide in DMBA - Induced rat liver [PDF]
, 2009 DMBA (7,12-dimethylbenz[a]anthracene) is known to generate DNA-reactive species during their metabolism, which may enhance oxidative stress in cells.
Talas, Zeliha Selamoglu +4 more
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Life, 2023 Since the first report of the organoselenium compound, ebselen, as a potent inhibitor of the SARS-CoV-2 Mpro main protease by Z. Jin et al. (Nature, 2020), different OSe analogs have been developed and evaluated for their anti-COVID-19 activities. Herein,
Saad Shaaban +7 more
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Organoselenium Compounds in Catalysis
Synthesis, 2023 AbstractIn this article we have focused on the use of selenium in catalysis along with the proposed reaction mechanisms. With increasing interest in selenium chemistry, we have highlighted the most significant features of this subject, mainly in the last years.
Juan B. Rodríguez +1 more
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Recent Advances in the Use of Diorganyl Diselenides as Versatile Catalysts
Molecules, 2023 The importance of organoselenium compounds has been increasing in synthetic chemistry. These reagents are well-known as electrophiles and nucleophiles in many organic transformations, and in recent years, their functionality as catalysts has also been ...
Gabriel Pereira da Costa +3 more
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Photocatalytic treatment of organoselenium in synthetic mine-impacted effluents
Water Science and Technology, 2023 Biological selenium reduction processes are commonly employed as the best available technology (BAT) for selenium removal; however, as a by-product they produce trace amounts of organoselenium compounds with orders of magnitude greater bioaccumulation ...
Jeffrey Thomas Martin +4 more
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Molecules, 2023 Due to problems with selenium deficiency in humans, the search for new organic molecules containing this element in plant biofortification process is highly required.
Paweł Zagrodzki +11 more
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Antiviral Effect of 5′-Arylchalcogeno-3-aminothymidine Derivatives in SARS-CoV-2 Infection
Molecules, 2023 The understanding that zidovudine (ZDV or azidothymidine, AZT) inhibits the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 and that chalcogen atoms can increase the bioactivity and reduce the toxicity of AZT has directed our search for the discovery ...
Amanda Resende Tucci +13 more
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Modular Generation of Alkyl Selenyl Radicals for the Synthesis of Alkyl Selenides via a Mechanochemical Approach. [PDF]
Adv Sci (Weinh)We present a mechanochemical, radical‐mediated hydroselenation of alkenes under ambient conditions. This method modularly generates alkyl selenyl radicals from elemental selenium and alkyl (pseudo)halides, utilizing PhSiH3 and H2O as hydrogen atom donors, with the water likely originating from the air and/or trace water present in the reagents ...
He X +8 more
europepmc +2 more sources
Design, Synthesis, and Biological Evaluation of Novel Hydroxamic Acid-Based Organoselenium Hybrids
Pharmaceuticals, 2023 We report the design and synthesis of novel hydroxamic acid-tethered organoselenium (OSe) hybrids. Their antimicrobial and anticancer activities were assessed against different microbes (e.g., Candida albicans (C. albicans), Escherichia coli (E.
Jameelah S. Alotaibi +2 more
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