Results 11 to 20 of about 2,820 (183)

The Effect of Organoselenium Compounds on Histone Deacetylase Inhibition and Their Potential for Cancer Therapy. [PDF]

Int J Mol Sci, 2021
Genetic and epigenetic changes alter gene expression, contributing to cancer. Epigenetic changes in cancer arise from alterations in DNA and histone modifications that lead to tumour suppressor gene silencing and the activation of oncogenes.
Adimulam T, Arumugam T, Foolchand A, Ghazi T, Chuturgoon AA.   +4 more
europepmc   +3 more sources

One-Pot Multicomponent Polymerization, Metal-, and Non-Metal-Catalyzed Synthesis of Organoselenium Compounds. [PDF]

Polymers (Basel), 2022
The one-pot multicomponent synthetic strategy of organoselenium compounds represents an alternative and robust protocol to the conventional multistep methods. During the last decade, a potential advance has been made in this domain. This review discusses
Shaaban S, El-Lateef HMA, Khalaf MM, Gouda M, Youssef I.   +4 more
europepmc   +3 more sources

Cytoprotective organoselenium compounds for oligodendrocytes

Arabian Journal of Chemistry, 2021
Abstract Herein we report the synthesis of peptide-like and tetrazole-based organoselenium compounds via Ugi and Ugi-azide reactions, respectively. The organoselenium compounds' intrinsic cytoprotective and antioxidant capacities were evaluated in 158 N and 158JP murine oligodendrocytes.
Saad Shaaban, Amira Zarrouk, Dominique Vervandier-Fasseur   +2 more
exaly   +2 more sources

Protective effects of organoselenium compounds against methylmercury-induced oxidative stress in mouse brain mitochondrial-enriched fractions

Brazilian Journal of Medical and Biological Research, 2011
We evaluated the potential neuroprotective effect of 1-100 µM of four organoselenium compounds: diphenyl diselenide, 3’3-ditri-fluoromethyldiphenyl diselenide, p-methoxy-diphenyl diselenide, and p-chloro-diphenyl diselenide, against methylmercury ...
D.F. Meinerz, M.T. de Paula, B. Comparsi, M.U. Silva, A.E. Schmitz, H.C. Braga, P.S. Taube, A.L. Braga, J.B.T. Rocha, A.L. Dafre, M. Farina, J.L. Franco, T. Posser   +12 more
doaj   +4 more sources

Organoselenium Compounds as Phytochemicals from the Natural Kingdom [PDF]

Natural Product Communications, 2015
Selenium is naturally present in soils but it is also produced by pollution from human activities into the environment. Its incorporation into plants affords organoselenium metabolites that, depending on the nature of the molecules and the plant species,
Hanane Achibat, Nohad A AlOmari, Federica Messina, Luca Sancineto, Mostafa Khouili, Claudio Santi   +5 more
doaj   +5 more sources

Organosulfur and Organoselenium Chemistry

Molecules
Organosulfur- and organoselenium-containing compounds play a crucial role in organic synthesis [...]
Ming Wang
doaj   +2 more sources

Inhibition of Development and Metabolism of Dual-Species Biofilms of Candida albicans and Candida krusei (Pichia kudriavzevii) by Organoselenium Compounds [PDF]

Pharmaceuticals
Although Candida albicans is the most frequently identified Candida species in clinical settings, a significant number of infections related to the non-albicans Candida (NAC) species, Candida krusei, has been reported.
Gabriela de Souza Calvi, Giulia Nicolle Jácome Cartaxo, Qiuxin Lin Carretoni, André Luiz Missio da Silva, Denilson Nogueira de Moraes, José Geraldo da Cruz Pradella, Maricilia Silva Costa   +6 more
doaj   +2 more sources

Lactiplantibacillus plantarum S1 as a Novel Dual-Functional Probiotic Strain for High-Efficiency Organoselenium Biotransformation in Functional Food Development [PDF]

Foods
The microbial conversion of inorganic Se into bioactive organoselenium compounds represents a cutting-edge strategy for developing functional foods with enhanced nutritional value.
Lin Yuan, Jianfeng Yuan, Chen Gao, Haoming Zhao, Chengye Wu, Zhong-Hua Yang   +5 more
doaj   +2 more sources

In Silico Investigation on the Binding of Organoselenium Compounds with Target Proteins of SARS-CoV-2 Infection Cycle

, 2020
Since the outbreak of coronavirus disease 2019 (COVID-19), researchers have been investigating the potential of several low molecular weight compounds from both natural and synthetic origins to design anti-viral drugs against SARS-CoV-2. On similar lines,
Singh BG, Kunwar A.
europepmc   +2 more sources

Synthesis, Characterization, and DFT Studies of NHC-Derived Amide-Functionalized Organoselenium Compounds [PDF]

ACS Omega
Ismat Nawaz, Muhammad Naeem Khan, Syed Tasadaque Ali Shah, Mohammed B. Hawsawi, Rahman Shah Zaib Saleem, Ghayoor Abbas Chotana   +5 more
doaj   +2 more sources