Interaction Profile of Diphenyl Diselenide with Pharmacologically Significant Thiols [PDF]
Molecules, 2012 Diphenyl diselenide has shown interesting biological activities in various free-radical-induced damage models and can be considered as a potential candidate drug against oxidative stress.
João Batista Teixeira Rocha
exaly +8 more sources
Differential genotoxicity of diphenyl diselenide (PhSe)2 and diphenyl ditelluride (PhTe)2 [PDF]
PeerJ, 2014 Organoselenium compounds have been pointed out as therapeutic agents. In contrast, the potential therapeutic aspects of tellurides have not yet been demonstrated.
Daiane Francine Meinerz +6 more
doaj +9 more sources
In Vitro Activity of Ebselen and Diphenyl Diselenide Alone and in Combination with Drugs against Trichophyton mentagrophytes Strains [PDF]
Pharmaceutics, 2022 Background: Dermatophytoses are one of the most prevalent infectious diseases in the world for which the pace of developing new drugs has not kept pace with the observed therapeutic problems.
Sebastian Gnat +5 more
doaj +3 more sources
Effect of Prepartum Maternal Supplementation with Diphenyl Diselenide on Biochemical, Immunological, and Oxidative Parameters of the Offspring [PDF]
Animals, 2023 This study aimed to assess the impact of prepartum maternal diphenyl diselenide (PhSe)2 supplementation on the development, biochemical, immune, and antioxidant parameters of calves.
Cláudia Medeiros Rodrigues +9 more
doaj +2 more sources
Diphenyl Diselenide-Assisted Radical Addition Reaction of Diphenyl Disulfide to Unsaturated Bonds upon Photoirradiation [PDF]
Molecules, 2023 The addition reaction of interelement compounds with heteroatom–heteroatom single bonds to unsaturated bonds under photoirradiation is an important method for the efficient and atom-economical construction of carbon–heteroatom bonds. However, in practice,
Yuki Yamamoto, Qiqi Chen, Akiya Ogawa
doaj +2 more sources
Effects of Diphenyl Diselenide on Methylmercury Toxicity in Rats [PDF]
BioMed Research International, 2013 This study investigates the efficacy of diphenyl diselenide [(PhSe)2] in attenuating methylmercury- (MeHg-)induced toxicity in rats. Adult rats were treated with MeHg [5 mg/kg/day, intragastrically (i.g.)] and/ or (PhSe)2[1 mg/kg/day, intraperitoneally (i.p.)] for 21 days.
Dalla Corte, Cristiane L. +8 more
openaire +3 more sources
Pharmacology and toxicology of diphenyl diselenide in several biological models [PDF]
Brazilian Journal of Medical and Biological Research, 2007 The pharmacology of synthetic organoselenium compounds indicates that they can be used as antioxidants, enzyme inhibitors, neuroprotectors, anti-tumor and anti-infectious agents, and immunomodulators.
R.M. Rosa +4 more
doaj +6 more sources
Antiproliferative Effect of Inorganic and Organic Selenium Compounds in Breast Cell Lines
Biomedicines, 2023 Triple-negative breast cancer (TNBC) is an aggressive, fast-growing tumor that is more likely to spread to distant organs. Among women diagnosed with breast cancer, the prevalence of TNBC is 20%, and treatment is currently limited to chemotherapy ...
Nayara Souza da Costa +7 more
doaj +1 more source
Brazilian Journal of Medical and Biological Research, 2011 We evaluated the potential neuroprotective effect of 1-100 µM of four organoselenium compounds: diphenyl diselenide, 3’3-ditri-fluoromethyldiphenyl diselenide, p-methoxy-diphenyl diselenide, and p-chloro-diphenyl diselenide, against methylmercury-induced
D.F. Meinerz +12 more
doaj +3 more sources
2-[Difluoro(phenylselenyl)methyl]benzo-1,3-thiazole
Molbank, 2022 This short note elaborates a concise protocol for the synthesis of 2-[difluoro(phenylselenyl)methyl]benzo-1,3-thiazole in two steps from the commercially available reagent 2-aminobenzenethiol.
Rongfu Xu +3 more
doaj +1 more source