Pharmacology and toxicology of diphenyl diselenide in several biological models [PDF]
The pharmacology of synthetic organoselenium compounds indicates that they can be used as antioxidants, enzyme inhibitors, neuroprotectors, anti-tumor and anti-infectious agents, and immunomodulators.
R.M. Rosa +4 more
doaj +6 more sources
Locust Bean Gum Nano-Based Hydrogel for Vaginal Delivery of Diphenyl Diselenide in the Treatment of Trichomoniasis: Formulation Characterization and In Vitro Biological Evaluation. [PDF]
Trichomoniasis is the most common nonviral sexually transmitted infection in the world, but its available therapies present low efficacy and high toxicity.
Reis FPD +5 more
europepmc +2 more sources
Diphenyl Diselenide Alleviates Tert-Butyl Hydrogen Peroxide-Induced Oxidative Stress and Lipopolysaccharide-Induced Inflammation in Rat Glomerular Mesangial Cells. [PDF]
Hyperglycemia, oxidative stress, and inflammation play key roles in the onset and development of diabetic complications such as diabetic nephropathy (DN). Diphenyl diselenide (DPDS) is a stable and simple organic selenium compound with anti-hyperglycemic,
Wang X +11 more
europepmc +2 more sources
Effects of diphenyl diselenide on methylmercury toxicity in rats. [PDF]
This study investigates the efficacy of diphenyl diselenide [(PhSe)2] in attenuating methylmercury- (MeHg-)induced toxicity in rats. Adult rats were treated with MeHg [5 mg/kg/day, intragastrically (i.g.)] and/ or (PhSe)2[1 mg/kg/day, intraperitoneally (i.p.)] for 21 days.
Dalla Corte CL +8 more
europepmc +4 more sources
Design and development of symmetric aromatic bischalcogenide-based photocatalysts for water treatment application: a concise study of diphenyl diselenide polypyrrole nanocatalysis. [PDF]
Dopant engineering can be a very selective approach in designing hybrid materials. Incorporating the required functionality in a dopant effectively modulates its properties towards aimed applications.
Jan T, Raheem S, Rizvi MA.
europepmc +2 more sources
In vitro anti-Cryptococcus activity of diphenyl diselenide alone and in combination with amphotericin B and fluconazole. [PDF]
Benelli JL +5 more
europepmc +2 more sources
Diphenyl diselenide alone and in combination with itraconazole against Sporothrix schenckii s.str. and Sporothrix globosa. [PDF]
Poester VR +5 more
europepmc +2 more sources
Antiproliferative Effect of Inorganic and Organic Selenium Compounds in Breast Cell Lines
Triple-negative breast cancer (TNBC) is an aggressive, fast-growing tumor that is more likely to spread to distant organs. Among women diagnosed with breast cancer, the prevalence of TNBC is 20%, and treatment is currently limited to chemotherapy ...
Nayara Souza da Costa +7 more
doaj +1 more source
We evaluated the potential neuroprotective effect of 1-100 µM of four organoselenium compounds: diphenyl diselenide, 3’3-ditri-fluoromethyldiphenyl diselenide, p-methoxy-diphenyl diselenide, and p-chloro-diphenyl diselenide, against methylmercury-induced
D.F. Meinerz +12 more
doaj +3 more sources
2-[Difluoro(phenylselenyl)methyl]benzo-1,3-thiazole
This short note elaborates a concise protocol for the synthesis of 2-[difluoro(phenylselenyl)methyl]benzo-1,3-thiazole in two steps from the commercially available reagent 2-aminobenzenethiol.
Rongfu Xu +3 more
doaj +1 more source

