Results 31 to 40 of about 1,907 (195)

2,2-Bis(phenylselanyl)-1-(p-tolyl)vinyl 2-Oxo-2-(p-tolyl)acetate

open access: yesMolbank, 2021
2,2-Bis(phenylselanyl)-1-(p-tolyl)vinyl 2-oxo-2-(p-tolyl)acetate was synthesized via the reaction of p-tolylacetylene with diphenyl diselenide and benzoyl peroxide in benzene under atmospheric conditions.
Shintaro Kodama   +7 more
doaj   +1 more source

Reduction of Diphenyl Diselenide and Analogs by Mammalian Thioredoxin Reductase Is Independent of Their Gluthathione Peroxidase-Like Activity: A Possible Novel Pathway for Their Antioxidant Activity

open access: yesMolecules, 2010
Since the successful use of the organoselenium drug ebselen in clinical trials for the treatment of neuropathological conditions associated with oxidative stress, there have been concerted efforts geared towards understanding the precise mechanism of ...
João Batista Teixeira Rocha   +7 more
doaj   +1 more source

Diphenyl diselenide a janus-faced molecule [PDF]

open access: yesJournal of the Brazilian Chemical Society, 2010
In this review, we summarized the potential role of synthetic organoseleno compounds as therapeutic or toxic agents, giving emphasis almost exclusively to diphenyl diselenide, the simplest of the diaryl diselenides, and some of its analogs. We presented the main molecular aspects related to the in vitro toxicity and pharmacology of diphenyl diselenide ...
Nogueira, Cristina W, Rocha, João B.T
openaire   +3 more sources

HEPATO-PROTECTIVE ROLE OF DIPHENYL DISELENIDE IN STREPTOZOTOCININDUCED DIABETIC RATS

open access: yesCOAST Journal of the School of Science, 2023
Diabetic hepatopathy prevalence as a result of prolonged hyperglycemia is increasing with the expanding size of the diabetes population around the world. In this present study, the hepato-protective activity of diphenyl diselenide (DPDSe) in a persistent
Fapetu Aanuoluwapo Patricia
semanticscholar   +1 more source

Chemical modifications of diphenyl diselenide enhance its anti-Sporothrix spp. activity and exhibit synergism with itraconazole. [PDF]

open access: yesBraz J Microbiol
Sporotrichosis is a globally distributed subcutaneous mycosis caused by fungi belonging to the Sporothrix genus. The limitations of current treatment options for sporotrichosis have driven an urgent search for new antifungal drugs.
Hidalgo JED   +10 more
europepmc   +2 more sources

Selenium-Catalyzed Reduction of Hydroperoxides in Chemistry and Biology

open access: yesAntioxidants, 2021
Among the chalcogens, selenium is the key element for catalyzed H2O2 reduction. In organic synthesis, catalytic amounts of organo mono- and di-selenides are largely used in different classes of oxidations, in which H2O2 alone is poorly efficient ...
Laura Orian, Leopold Flohé
doaj   +1 more source

Cesium Carbonate-Catalyzed α-Phenylchalcogenation of Carbonyl Compounds with Diphenyl Dichalcogenide

open access: yesMolecules, 2009
It was found that cesium carbonate has a unique catalytic ability on the reaction of carbonyl compounds with diphenyl diselenide to give the corresponding α-phenylseleno carbonyl compounds in moderate to good yields.
Yutaka Nishiyama   +3 more
doaj   +1 more source

Catalytic Antioxidant Activity of Bis-Aniline-Derived Diselenides as GPx Mimics

open access: yesMolecules, 2021
Herein, we describe a simple and efficient route to access aniline-derived diselenides and evaluate their antioxidant/GPx-mimetic properties. The diselenides were obtained in good yields via ipso-substitution/reduction from the readily available 2 ...
Giancarlo V. Botteselle   +11 more
doaj   +1 more source

A Simple Zinc-Mediated Method for Selenium Addition to Michael Acceptors

open access: yesMolecules, 2020
In this work, we focused our attention on seleno-Michael type reactions. These were performed using zinc-selenolates generated in situ from diphenyl diselenide 1, 1,2-bis(3-phenylpropyl)diselenide 30, and protected selenocystine 31 via an efficient ...
Francesca Giulia Nacca   +4 more
doaj   +1 more source

Promoting the sulfur redox kinetics by mixed organodiselenides in high-energy-density lithium–sulfur batteries

open access: yeseScience, 2021
Lithium–sulfur (Li–S) batteries are considered as a highly promising energy storage system due to their ultrahigh theoretical energy density. However, the sluggish kinetics of the complex multi-electron sulfur redox reactions seriously hinders the actual
Meng Zhao   +6 more
doaj   +1 more source

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