Results 31 to 40 of about 63,745 (188)
Diphenyl diselenide a janus-faced molecule [PDF]
Journal of the Brazilian Chemical Society, 2010 In this review, we summarized the potential role of synthetic organoseleno compounds as therapeutic or toxic agents, giving emphasis almost exclusively to diphenyl diselenide, the simplest of the diaryl diselenides, and some of its analogs. We presented the main molecular aspects related to the in vitro toxicity and pharmacology of diphenyl diselenide ...
Nogueira, Cristina W, Rocha, João B.T
openaire +3 more sources
Carbocyclization by Radical Closure onto O-Trityl Oximes: Dramatic Effect of Diphenyl Diselenide
, 2016 O-Trityl oximes of 5- and 6-iodoaldehydes undergo radical cyclization to produce oximes when treated in refluxing tetrahydrofuran (THF) with Bu3SnH, 1,1‘-azobis(cyclohexanecarbonitrile), i-Pr2NEt, and diphenyl diselenide (PhSeSePh)
Derrick L. J. Clive (1457011) +2 more
core +4 more sources
Cesium Carbonate-Catalyzed α-Phenylchalcogenation of Carbonyl Compounds with Diphenyl Dichalcogenide
Molecules, 2009 It was found that cesium carbonate has a unique catalytic ability on the reaction of carbonyl compounds with diphenyl diselenide to give the corresponding α-phenylseleno carbonyl compounds in moderate to good yields.
Yutaka Nishiyama +3 more
doaj +1 more source
Selenium-Catalyzed Reduction of Hydroperoxides in Chemistry and Biology
Antioxidants, 2021 Among the chalcogens, selenium is the key element for catalyzed H2O2 reduction. In organic synthesis, catalytic amounts of organo mono- and di-selenides are largely used in different classes of oxidations, in which H2O2 alone is poorly efficient ...
Laura Orian, Leopold Flohé
doaj +1 more source
Catalytic Antioxidant Activity of Bis-Aniline-Derived Diselenides as GPx Mimics
Molecules, 2021 Herein, we describe a simple and efficient route to access aniline-derived diselenides and evaluate their antioxidant/GPx-mimetic properties. The diselenides were obtained in good yields via ipso-substitution/reduction from the readily available 2 ...
Giancarlo V. Botteselle +11 more
doaj +1 more source
A Simple Zinc-Mediated Method for Selenium Addition to Michael Acceptors
Molecules, 2020 In this work, we focused our attention on seleno-Michael type reactions. These were performed using zinc-selenolates generated in situ from diphenyl diselenide 1, 1,2-bis(3-phenylpropyl)diselenide 30, and protected selenocystine 31 via an efficient ...
Francesca Giulia Nacca +4 more
doaj +1 more source
New therapeutic approach: diphenyl diselenide reduces mitochondrial dysfunction in acetaminophen-induced acute liver failure. [PDF]
PLoS ONE, 2013 The acute liver failure (ALF) induced by acetaminophen (APAP) is closely related to oxidative damage and depletion of hepatic glutathione, consequently changes in cell energy metabolism and mitochondrial dysfunction have been observed after APAP overdose.
Nélson R Carvalho +8 more
doaj +1 more source
eScience, 2021 Lithium–sulfur (Li–S) batteries are considered as a highly promising energy storage system due to their ultrahigh theoretical energy density. However, the sluggish kinetics of the complex multi-electron sulfur redox reactions seriously hinders the actual
Meng Zhao +6 more
doaj +1 more source
Over-activation of the Drosophila melanogaster hsp83 gene by selenium intoxication
Genetics and Molecular Biology, 2008 Selenium is an important dietary micronutrient and an essential component of selenoproteins and the active sites of some enzymes, although at high concentrations it is toxic.
Ronaldo Medeiros Golombieski +4 more
doaj +1 more source
Diphenyl diselenide supplemented diet reduces depressive-like behavior in hypothyroid female rats [PDF]
, 2014 Hypothyroidism has been associated to psychiatric disorder development and tissue oxidative damage. In this study, we evaluated the effect of diphenyl diselenide supplementation on depressive-like behavior triggered by methimazole exposure in female rats.
Dias, Glaecir Roseni Mundstock +7 more
core +1 more source