Results 61 to 70 of about 1,574,989 (184)

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

HYPERCOORDINATED ORGANOSELENIUM COMPOUNDS WITH O→Se INTRAMOLECULAR INTERACTIONS

Studia Universitatis Babes-Bolyai Chemia, 2017
Single-crystal X-ray diffraction studies revealed a monomeric structure with O→Se intramolecular coordination in compounds [Me2C(OH)CH2][2-(Me2NCH2)C6H4]Se (1) and [2-(O=CH)C6H4]Se[S(S)P(OPri)2] (2).
Alexandra POP, Roxana Alexandra POPA, Cristian SILVESTRU, Anca SILVESTRU   +3 more
doaj   +1 more source

Enantioselective Catalysis for the Preparation of Organoselenium Compounds and Applications

, 2014
The peculiar reactivity and the interesting biological properties of chiral organoselenium compounds inspired organic chemists to develop new methodologies for their synthesis.
MARINI, Francesca, STERNATIVO, Silvia, BAGNOLI, Luana   +2 more
core   +1 more source

Organoselenium Compounds: Chemistry and Applications in Organic Synthesis

Chemistry – A European Journal, 2023
AbstractSelenium, originally described as a toxin, turns out to be a crucial trace element for life that appears as selenocysteine and its dimer, selenocystine. From the point of view of drug developments, selenium‐containing drugs are isosteres of sulfur and oxygen with the advantage that the presence of the selenium atom confers antioxidant ...
Juan M. Sonego, Sheila I. de Diego, Sergio H. Szajnman, Carola Gallo‐Rodriguez, Juan B. Rodriguez   +4 more
openaire   +3 more sources

Facile Access to 2-Selenoxo-1,2,3,4-tetrahydro-4-quinazolinone Scaffolds and Corresponding Diselenides via Cyclization between Methyl Anthranilate and Isoselenocyanates: Synthesis and Structural Features

Molecules, 2022
A practical method for the synthesis of 2-selenoxo-1,2,3,4-tetrahydro-4-quinazolinone was reported. The latter compounds were found to undergo facile oxidation with H2O2 into corresponding diselenides.
Vladimir K. Osmanov, Evgeniy V. Chipinsky, Victor N. Khrustalev, Alexander S. Novikov, Rizvan Kamiloglu Askerov, Alexander O. Chizhov, Galina N. Borisova, Alexander V. Borisov, Maria M. Grishina, Margarita N. Kurasova, Anatoly A. Kirichuk, Alexander S. Peregudov, Andreii S. Kritchenkov, Alexander G. Tskhovrebov   +13 more
doaj   +1 more source

Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds

The Chemical Record, EarlyView.
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá, Patrick C. Nobre, Isabelly O. Ferreira, Juliano B. Azeredo, Vanessa Nascimento   +4 more
wiley   +1 more source

Green solvents in organoselenium chemistry [PDF]

, 2019
© 2018, Springer Nature Switzerland AG. Organoselenium chemistry involves unique methods for the preparation of reaction intermediates and biologically relevant compounds.
Divac, Vera, Kostic, Marina
core   +1 more source

Influence of nanohydroxyapatite mouthwash on the growth of Candida albicans biofilm on milled denture surfaces: An in vitro study

Journal of Prosthodontics, EarlyView.
Abstract Purpose There is a need for effective solutions for the persistent prevalence of denture stomatitis (DS) in denture‐wearing populations. This study assessed the impact of nanohydroxyapatite (nanoHAP) nanoparticles on Candida albicans biofilm formation on milled polymethylmethacrylate (PMMA) denture bases.
Cynthia U. Udeh, Bennett T. Amaechi, Parveez A. Abdul‐Azees, Amos C. Obiefuna, Chun‐Yen Lin, Nahid IftiKhar, Sunil Mankar, Temitope O. Omosebi, Tejal Gohil   +8 more
wiley   +1 more source

Síntese e avaliação do potencial antioxidante de compostos biologicamente importantes contendo selênio [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015.O presente trabalho trata do planejamento e síntese de moléculas biologicamente importantes ...
Nascimento, Vanessa do
core  

Synthesis of Selenium-Based Small Molecules Inspired by CNS-Targeting Psychotropic Drugs and Mediators

Chemistry, 2023
Due to its endogenously high oxygen consumption, the central nervous system (CNS) is vulnerable to oxidative stress conditions. Notably, the activity of several CNS-targeting compounds, such as antidepressant and hypnotic drugs, or endogenous mediators ...
Giovanni Ribaudo, Davide Zeppilli, Alberto Ongaro, Marco Bortoli, Giuseppe Zagotto, Laura Orian   +5 more
doaj   +1 more source