Results 81 to 90 of about 1,574,989 (184)

Catalytic Antioxidant Activity of Acyclic and Macrocyclic Selenides: Insights Into Structure–Activity Relationships and Mechanisms From Kinetic and Computational Studies

European Journal of Organic Chemistry, Volume 29, Issue 27, 17 July 2026.
Structure–activity relationships of antioxidant activities of selenides were established by experimental and computational methods. Several structures displayed strong catalytic activity in an NMR‐based assay. Diverse selenides were shown to act as potent catalytic antioxidants.
Adrian I. Doig, Wen Zhou, Thomas G. Back
wiley   +1 more source

Thioredoxin Reductase as a Target for Antibacterial Gold Compounds in Burkholderia cenocepacia: Disclosing the Molecular Basis of Enzyme Inhibition

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
The molecular basis of thioredoxin reductase inhibition by antibacterial gold(I) compounds is disclosed. X‐ray crystallography and high‐resolution ESI‐MS reveal selective gold coordination to catalytically relevant cysteine residues of Bc‐TrxR, leading to stable protein–gold adducts and disruption of enzyme redox activity.
Stefano Zineddu, José Aleixo de Azevedo‐França, Martina Aguanno, Valentina Pecchioli, Giarita Ferraro, Virginia Cuomo, Antonello Merlino, Luigi Messori   +7 more
wiley   +1 more source

Organoselenium-Catalyzed Asymmetric Cyclopropanations of (E)‑Chalcones

We report a new class of chiral tetrahydroselenophene based on (S)-diphenyl­(tetrahydroselenophen-2-yl)­methanol, which was prepared from (R)-3-(3-bromopropyl)-2,2-diphenyloxirane and sodium selenide.
Rong-Jie Chein (1796227), Yu-Hsun Tseng (11529195), Pei-Tung Cheng (11529192)   +2 more
core   +1 more source

Isolation and Structural Characterization of Se‐Hügerschoff Intermediates Derived From 4‐Bromoaniline

Journal of Heterocyclic Chemistry, Volume 63, Issue 6, Page 1004-1009, June 2026.
Isolation and characterization of Se‐brominated Hügerschoff intermediates enable structural and mechanistic insight into seleno‐Hügerschoff cyclization to 2‐aminobenzoselenazoles. ABSTRACT A brominated intermediate within the Hügerschoff reaction has long been postulated but never directly observed.
Adam W. E. Stewart, Tom Fellows, Lucy Li, Craig J. Morton, Glen P. Carter, Jonathan M. White   +5 more
wiley   +1 more source

Atividade de selenetos e selenóxidos como miméticos da enzima glutationa peroxidase: revisão do ciclo catalítico [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2011O presente trabalho apresenta a síntese de uma série de selenetos e selenóxidos com grande
Nascimento, Vanessa do
core  

Nitric Oxide‐Generating Poly (allylamine hydrochloride) Coating on Biomedical Titanium Implant

Advanced Materials Interfaces, Volume 13, Issue 10, 19 May 2026.
We report a metal‐free, nitric oxide (NO)‐generating coating in which poly(allylamine hydrochloride) (PAH) is covalently immobilized onto titanium. The coating catalyzes NO generation from the endogenous S‐nitrosothiol GSNO, retains activity after multiple reuse cycles and pH exposures, and maintains endothelial cell viability while modulating ...
Siti Nur Asyura Adzlan, Kang Lin, Shu Geng, Qingqing Fan, Franco Centurion, Zifei Han, Federico Mazur, Rona Chandrawati   +7 more
wiley   +1 more source

Selenium-Epoxy ‘Click’ Reaction and Se-Alkylation—Efficient Access to Organo-Selenium and Selenonium Compounds

Chemistry, 2020
This work establishes the ‘click’ nature of the base-catalyzed oxirane ring opening reaction by the selenolate nucleophile. The ‘click’-generated ß-hydroxy selenide can be alkylated to afford cationic selenium species.
Taejun Eom, Anzar Khan
doaj   +1 more source

Modular Generation of Alkyl Selenyl Radicals for the Synthesis of Alkyl Selenides via a Mechanochemical Approach

Advanced Science, Volume 13, Issue 28, 18 May 2026.
We present a mechanochemical, radical‐mediated hydroselenation of alkenes under ambient conditions. This method modularly generates alkyl selenyl radicals from elemental selenium and alkyl (pseudo)halides, utilizing PhSiH3 and H2O as hydrogen atom donors, with the water likely originating from the air and/or trace water present in the reagents ...
Xiaochun He, Yu Zhou, Fei Zhou, Zixi Ai, Peiyu Hu, Xuemei Zhang, Xiaofeng Wei, Gui‐Juan Cheng, Zhong Lian   +8 more
wiley   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Organoselenium-Catalyzed C2,3-Diarylation of N–H Indoles

An organoselenium-catalyzed C2,3-diarylation of unprotected N–H indoles with electron-rich aromatics has been developed. This one-pot multicomponent tandem cross-dehydrogenation coupling reaction allows for the incorporation of two different aromatic ...
Taoyuan Liang (4840839), Yingying Zhang (42910), Zongwu Wei (12213759), Zhuan Zhang (3355382), Xiaoxiang Zhang (628483), Junqiu Liao (16698080)   +5 more
core   +1 more source