Results 61 to 70 of about 1,126,709 (293)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Equitable orientations of sparse uniform hypergraphs [PDF]
, 2016 Caro, West, and Yuster studied how $r$-uniform hypergraphs can be oriented in such a way that (generalizations of) indegree and outdegree are as close to each other as can be hoped.
Cohen, Nathann, Lochet, William
core +3 more sources
Orientation-dependent C60 electronic structures revealed by photoemission
, 2004 We observe, with angle-resolved photoemission, a dramatic change in the electronic structure of two C60 monolayers, deposited respectively on Ag (111) and (100) substrates, and similarly doped with potassium to half-filling of the C60 lowest unoccupied ...
A. Goldoni +13 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Espaço Ameríndio, 2011 Clique no link abaixo para baixar o arquivo completo em ...
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doaj +6 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Reviews on Advanced Materials ScienceIn industry, synthetic fibre reinforcements are popular due to their cost-effectiveness and lightweight nature. However, the non-reusability and non-degradability have raised environmental concerns and prompted scientists to explore more environmentally ...
Shalwan Abdullah +2 more
doaj +1 more source
Acyclic orientations on the Sierpinski gasket
, 2010 We study the number of acyclic orientations on the generalized two-dimensional Sierpinski gasket $SG_{2,b}(n)$ at stage $n$ with $b$ equal to two and three, and determine the asymptotic behaviors.
Biggs N. L. +6 more
core +1 more source
Journal of Mathematical Analysis and Applications, 1996 This paper deals with the range of vector-valued measures. The main purpose is to clarify the well-known Lyapunov convexity theorem for vector-valued measures on a real interval \([a,b]\). A vector measure \(\mu=(\mu_1,\dots,\mu_n)\) on \([a,b]\) is an oriented measure if it is nonatomic and if for each \(k\)-tuple \((1\leq k\leq n)\) of disjoint ...
R. Cerf, MARICONDA, CARLO
openaire +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source