Results 91 to 100 of about 6,229 (187)

Development of a rapid and visual nucleotide detection method for a Chinese epidemic strain of Orientia tsutsugamushi based on recombinase polymerase amplification assay and lateral flow test

International Journal of Infectious Diseases, 2018
Objectives: Orientia tsutsugamushi is an obligate intracellular pathogen that causes scrub typhus. Diagnosing scrub typhus remains a challenge, and a sensitive, specific, simple, and rapid diagnostic test is still needed.
Yong Qi, Qiong Yin, Yinxiu Shao, Min Cao, Suqin Li, Hongxia Chen, Wanpeng Shen, Jixian Rao, Jiameng Li, Xiaoling Li, Yu Sun, Yu Lin, Yi Deng, Wenwen Zeng, Shulong Zheng, Suyun Liu, Yuexi Li   +16 more
doaj   +1 more source

Scrub Typhus Combined With Septic Shock Disseminated Intravascular Coagulation and Significant Hyperfibrinolysis: A Case Report and Review of the Literature

Case Reports in Infectious Diseases, Volume 2025, Issue 1, 2025.
Introduction: Scrub typhus is an acute infectious disease caused by Orientia tsutsugamushi, whose pathophysiology is characterized by systemic small‐vessel vasculitis. Its high misdiagnosis rate stems from its nonspecific clinical features. If not diagnosed and treated in time, patients may rapidly progress to multiorgan dysfunction syndrome (MODS) or ...
Dewen Ma, Xiaohong Wan, Haihui Yang, Liying Yang, Ankang Peng, Quping Yuan, You Li, Shunhang Xu, Larry M. Bush   +8 more
wiley   +1 more source

Genome-Based Construction of the Metabolic Pathways of Orientia tsutsugamushi and Comparative Analysis within the Rickettsiales Order [PDF]

, 2008
Orientia tsutsugamushi, the causative agent of scrub typhus, is an obligate intracellular bacterium that belongs to the order of Rickettsiales. Recently, we have reported that O.
Cho, Nam-Hyuk, Choi, Myung-Sik, Kim, Ik-Sang, Kim, Sanguk, Min, Chan-Ki, Yang, Jae-Seong   +5 more
core   +3 more sources

Clinical, Laboratory Characteristics, and Microorganism Infection Status in Neonates With Meningitis in Vietnam: A Cross‐Sectional Descriptive Study

International Journal of Pediatrics, Volume 2025, Issue 1, 2025.
Objective This study is aimed at describing the clinical and laboratory characteristics and determining the prevalence of microbial pathogens causing neonatal meningitis detected by cerebrospinal fluid (CSF) real‐time polymerase chain reaction (PCR). Materials and Methods A cross‐sectional descriptive study was conducted on 55 neonates diagnosed with ...
Tho Kieu Anh Pham, Binh Thien Nguyen, Phuong Minh Nguyen, Khai Quang Tran, Nikhat Kaura   +4 more
wiley   +1 more source

Wildlife Pathogens and Zoonotic Disease Risk Assessment in Vietnam: A Wildlife Trade Hotspot

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Vietnam is a wildlife trade hotspot presenting multiple high‐risk interfaces for pathogen spillover from wildlife to humans. However, the zoonotic disease risk remains poorly characterized in the country and needs to be assessed to better inform policy dialog and legislative reforms.
Alice Latinne, Pawin Padungtod, Fedor Korennoy   +2 more
wiley   +1 more source

Genetic diversity of Orientia tsutsugamushi strains from patients in north India

International Journal of Infectious Diseases, 2019
Background: Scrub typhus has emerged as a major cause of acute febrile illness in India in recent years. The causative agent, Orientia tsutsugamushi has more than 20 prototype strains due to a variable 56-kDa outer membrane protein. It is crucial to know
Abhay Kumar, Manisha Biswal, Kamran Zaman, Navneet Sharma, Vikas Suri, Ashish Bhalla   +5 more
doaj   +1 more source

Lack of Effect of Dexamethasone on Growth of Orientia Tsutsugamushi Gilliam in Mouse L929 Cells [PDF]

, 2011
PURPOSE: Previous studies and our own clinical experience suggest that concurrent corticosteroid treatment for severe rickettsial disease with multiorgan failure may improve the clinical course or reduce mortality.
Ae Jung Huh, Annane, Breitschwerdt, Briegel, Brown, Bum Sik Chin, Chang, Chang Oh Kim, Choe, Choi, Cronin, Davidson, Hansen, Hanson, Jerrells, Joon Sup Yeom, Jun Yong Choi, June Myung Kim, Kkot Sil Lee, Laffin, Lefering, Peck, Sang Hoon Han, Song, Su Jin Jeong, Takami, Tamura, Tasneen, Tsuruhara, Walker, Watt, Workman, Young Goo Song   +32 more
core   +2 more sources

Syk-Dependent Responses and Innate Cytosolic Defenses in Orientia tsutsugamushi-infected Macrophages [PDF]

, 2023
Lynn Soong, James R. Fisher, Casey Gonzales, Yuejin Liang   +3 more
openalex   +1 more source

Functional Analysis of an Orientia tsutsugamushi Ankyrin Effector Protein in a Model Eukaryote [PDF]

, 2019
Orientia tsutsugamushi is an understudied, gram negative, obligate intracellular bacterium that is transmitted by mites within the genus Leptotrombidium.
Bartlett, Dylan
core  

A case of neonatal tsutsugamushi disease diagnosed with the aid of rickettsial macrogenomic detection

BMC Pediatrics
Background Tsutsugamushi, also known as bush typhus, is a naturally occurring disease caused by Orientia tsutsugamushi. We reported a case of vertical mother-to-newborn transmission of Orientia tsutsugamushi infection in a newborn from Yunnan (China ...
Xu Yang, Ling Zhang, Shanping Chen, Wei Chen, Yushan Zhang, Yi Zhang, Jialong Liang, Ying Lv, Weiyan Wang, Yini Zhou, Rui Huang, Dongju Pan, Xueyu Li, Qiurong Li   +13 more
doaj   +1 more source