Results 61 to 70 of about 5,605 (215)

Diagnosis of Rickettsial infection by Multiplex Real-time PCR in Febrile Pediatric Patients Admitted in a Tertiary Care Hospital at Chennai, South India

Journal of Pure and Applied Microbiology
Rickettsioses caused by Rickettsia and Orientia spp. are the re-emerging diseases in India, which are grossly underdiagnosed, particularly among children.
Rajagopal Murali, Sivasambo Kalpana, Karthick Shanmugam, Prabu Dhandapani   +3 more
doaj   +1 more source

Scrub Typhus Outbreak in Chonburi Province, Central Thailand, 2013

Emerging Infectious Diseases, 2018
Investigation of a scrub typhus outbreak in Thailand during September 2013 found that 9.1% of Thai soldiers and 11.1% of residents living in areas surrounding training sites had antibodies against the causative agent, Orientia tsutsugamushi.
Wuttikon Rodkvamtook, Narupon Kuttasingkee, Piyada Linsuwanon, Yutthapong Sudsawat, Allen L. Richards, Maneerat Somsri, Noppadon Sangjun, Chien-Chung Chao, Silas Davidson, Elizabeth Wanja, Jariyanart Gaywee   +10 more
doaj   +1 more source

Neglected scrub typhus: An updated review with a focus on omics technologies

Asian Pacific Journal of Tropical Medicine, 2022
Scrub typhus is a neglected disease and one of the most serious health problems in the Asia-Pacific region. The disease is caused by an obligate intracellular bacteria Orientia tsutsugamushi, which is transmitted by chigger bites or larval mite bites ...
Dixit Sharma, Ankita Sharma, Birbal Singh, Sunil Kumar, Shailender Kumar Verma   +4 more
doaj   +1 more source

A Metabolic Dependency for Host Isoprenoids in the Obligate Intracellular Pathogen Rickettsia parkeri Underlies a Sensitivity to the Statin Class of Host-Targeted Therapeutics. [PDF]

, 2019
Gram-negative bacteria in the order Rickettsiales have an obligate intracellular growth requirement, and some species cause human diseases such as typhus and spotted fever.
Ahyong, Vida, Berdan, Charles A, Burke, Thomas P, Nomura, Daniel K, Welch, Matthew D   +4 more
core   +2 more sources

435. Serological Cross-Reactivity Between Rickettsia japonica and Orientia tsutsugamushi, and Among Orientia tsutsugamushi Serotypes [PDF]

Open Forum Infectious Diseases, 2018
BACKGROUND: The rickettsial diseases Japanese spotted fever (JSF) and scrub typhus (ST) are caused by Rickettsia japonica and Orientia tsutsugamushi, respectively. The diseases share clinical symptoms, such as fever, rash, and eschar. However, there are no systematical investigations of the serological cross-reactivity between R.
Sando, Eiichiro, Ariyoshi, Koya, Fujita, Hiromi   +2 more
openaire   +1 more source

Identification of Potential Therapeutic Agents for Primary Amebic Meningoencephalitis Using Text Mining and Bioinformatics Analyses

Analytical Cellular Pathology, Volume 2026, Issue 1, 2026.
Naegleria fowleri, the brain‐eating ameba, causes primary amebic meningoencephalitis (PAM), a fatal infectious disease that affects the central nervous system (CNS). We aimed to evaluate the functions and potential drugs targeting PAM using text mining and bioinformatics analyses.
Eun Jung Sohn, Hyeonseo Jo, Kun Taek Park, Andrey Elchaninov   +3 more
wiley   +1 more source

A Rare and Severe Multisystem Cascade of AKI, ARDS, and Septic Shock Leading to Acalculous Cholecystitis in a Young Scrub Typhus Patient: A Case Report From Nepal

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Scrub typhus, caused by Orientia tsutsugamushi, is an acute febrile illness prevalent in Nepal with a wide spectrum of clinical presentations. Severe forms can lead to multiorgan dysfunction, including acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), septic shock, and rarely, acalculous cholecystitis.
Prabhat Kaphle, Maya Upadhyaya, Sarjan Shrestha, Amrita Shrestha, Dhanlaxmi Giri, Kamal Hamal, Liladhar Ojha   +6 more
wiley   +1 more source

New Orientia tsutsugamushi Strain from Scrub Typhus in Australia

Emerging Infectious Diseases, 1998
In a recent case of scrub typhus in Australia, Orientia tsutsugamushi isolated from the patient's blood was tested by sequence analysis of the 16S rDNA gene. The sequence showed a strain of O. tsutsugamushi that was quite different from the classic Karp,
Dimitri M. Odorico, Stephen R. Graves, Bart J. Currie, Julian Catmull, Zoltan Nack, Sharon Ellis, Ling Wang, David J. Miller   +7 more
doaj   +1 more source

CD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection. [PDF]

PLoS Neglected Tropical Diseases, 2017
Scrub typhus, caused by a Gram-negative obligately intracellular coccobacillus, Orientia tsutsugamushi, is a long neglected but important tropical disease. Orientia tsutsugamushi causes illness in one million people each year, and 1 billion people are at
Guang Xu, Nicole L Mendell, Yuejin Liang, Thomas R Shelite, Yenny Goez-Rivillas, Lynn Soong, Donald H Bouyer, David H Walker   +7 more
doaj   +1 more source

Seroprevalence and Genotypic Characterization of Orientia tsutsugamushi in Febrile Pediatric Patients Admitted in Tertiary Care Hospital of Chennai, South India

Journal of Pure and Applied Microbiology, 2023
Scrub typhus is one of the important vector borne illness which is largely underdiagnosed, particularly in children. It causes mild febrile illness to severe complications.
Rajagopal Murali, Sivasambo Kalpana, Panneerselvam Satheeshkumar, Prabu Dhandapani   +3 more
doaj   +1 more source