Results 181 to 190 of about 838,055 (333)

Creating a foundation for origin of life outreach: How scientists relate to their field, the public, and religion. [PDF]

PLoS One, 2023
Wienand K, Kampschulte L, Heckl WM.
europepmc   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

The Legend of ATP: From Origin of Life to Precision Medicine. [PDF]

Metabolites, 2022
Chu XY, Xu YY, Tong XY, Wang G, Zhang HY.   +4 more
europepmc   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Bio-mediated CN cycling in serpentinites and the origin of life. [PDF]

Sci Rep
Tenuta S, Evans KA, Reddy SM, Tutolo BM, Rickard WDA, Saxey DW.   +5 more
europepmc   +1 more source

RNA enigma: "From origin of life to novel Coronavirus-COVID-19". [PDF]

Saudi J Biol Sci, 2022
Krishnaveni M, Venkatesh S.
europepmc   +1 more source

The Chinese Six Companies: A Short, General Historical Resume of Its Origin, Function, and Importance in the Life of the California Chinese

, 1944
John Walton Caughey, William Hoy
openalex   +2 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Oxidative stress in pediatric diseases associated with the origin of life and growth and development. [PDF]

Front Cell Dev Biol
Zheng B, Fu J.
europepmc   +1 more source

New Insights on the Origin of Life: The Role of Silico-Carbonates of Ba (II) to Preserve DNA against Highly Intense UV Radiation. [PDF]

ACS Omega, 2023
Cuéllar-Cruz M.
europepmc   +1 more source