Results 291 to 300 of about 598,816 (344)

Cybernetic origins of replication

Origins of life and evolution of the biosphere, 1988
An evolutionary progression leading toward replication is resolved into several phases; (a) the replication of RNA segments by self-priming and -templating, (b) the replication of single stranded molecules by elongation and controlled scission, (c) replication of complementary duplexes and (d) replication of DNA.
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The replication origin of Azotobacter vinelandii

Molecular and General Genetics MGG, 2000
The putative replication origin of Azotobacter vinelandii was cloned as an autonomously replicating fragment after ligation to an antibiotic resistance cartridge. The resulting plasmids could be isolated and labelled by Southern hybridisation with the antibiotic resistance cartridge as probe and also visualised by electron microscopy.
R A, Singh, N R, Choudhury, H K, Das
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The regulation of replication origin activation

Current Opinion in Genetics & Development, 1999
At the start of the cell-division programme, proteins must be assembled onto replication origins to establish competence for initiation of DNA synthesis. At the correct moment, other effectors must then coordinate appropriate firing of the various origins to control entry into and progress through S phase.
Donaldson, Anne D., Blow, J. Julian
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The Origin of Adenovirus DNA Replication

1983
Current efforts to understand regulation of replication and cell growth often focus on initiation of DNA replication at an origin sequence. It is most likely, although not yet proven in eukaryotes, that the ultimate step in the regulation of the G to S transition in the cell cycle is the priming of DNA synthesis at an origin.
Tamanoi, F., Stillman, B. W.
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Bacterial chromosome origins of replication

Current Opinion in Genetics & Development, 1993
Bacteria regulate chromosomal replication from one specific origin. We compare the regulatory requirements, DNA structures, and biochemical properties of the prototypic Escherichia coli origin with those of evolutionarily distant Bacillus subtilis and Caulobacter crescentus origins.
G T, Marczynski, L, Shapiro
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Unwinding of duplex DNA from the SV40 origin of replication by T antigen.

Science, 1987
The T antigen specified by SV40 virus is the only viral-encoded protein required for replication of SV40 DNA. T antigen has two activities that appear to be essential for viral DNA replication: specific binding to duplex DNA at the origin of replication ...
M. Dodson, F. Dean, P. Bullock, H. Echols, J. Hurwitz   +4 more
semanticscholar   +1 more source

Multiple origins of replication in archaea

Trends in Microbiology, 2004
Until recently, the only archaeon for which a bona fide origin of replication was reported was Pyrococcus abyssi, where a single origin was identified. Although several in silico analyses have suggested that some archaeal species might contain more than one origin, this has only been demonstrated recently.
Lori M, Kelman, Zvi, Kelman
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Unearthing worm replication origins

Nature Structural & Molecular Biology, 2017
Unlike in animals in which gastrulation marks the onset of zygotic transcription and a transition from random to site-specific localization of replication origins, transcription and origin specification in Caenorhabditis elegans are in place before gastrulation.
Takayo, Sasaki, David M, Gilbert
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Probing replication origins with a fork

Trends in Cell Biology, 1991
In 1968, Huberman and Riggs used DNA-fibre autoradiography to dem- onstrate that the replication of eukaryotic chromosomes occurs bi- directionally from multiple discrete sites that appear to be irregularly spaced along the chromosome t. Since then, the specific sequence requirements of prokaryotic and viral replication origins have been well ...
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Origins of replication and gene regulation

Molecular and Cellular Biochemistry, 1984
Eukaryotic chromosomes appear to consist of many replicons, the time of replication of which is probably controlled by specific origins. However, plasmids without specific eukaryotic origins may also replicate in some cells when injected into nuclei or transferred during transformation.
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