Results 101 to 110 of about 14,422 (161)

SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations. [PDF]

Cell Rep, 2022
Anderson EM, Li SH, Awofolaju M, Eilola T, Goodwin E, Bolton MJ, Gouma S, Manzoni TB, Hicks P, Goel RR, Painter MM, Apostolidis SA, Mathew D, Dunbar D, Fiore D, Brock A, Weaver J, Millar JS, DerOhannessian S, UPenn COVID Processing Unit, Greenplate AR, Frank I, Rader DJ, Wherry EJ, Bates P, Hensley SE.   +25 more
europepmc   +1 more source

Back to the Future: Immune Protection or Enhancement of Future Coronaviruses

Microorganisms
Before the emergence of SARS-CoV-1, MERS-CoV, and most recently, SARS-CoV-2, four other coronaviruses (the alpha coronaviruses NL63 and 229E and the beta coronaviruses OC43 and HKU1) had already been circulating in the human population. These circulating
Merit Bartels, Eric Sala Solé, Lotte M. Sauerschnig, Ger T. Rijkers   +3 more
doaj   +1 more source

Original antigenic sin: A potential double-edged effect for vaccine improvement

Biomedicine & Pharmacotherapy
Original antigenic sin (OAS) influences the immune response to subsequent infections with related variants following initial pathogen exposure. This phenomenon is characterized by cross-reactivity, which, although it may worsen infections, also provides a degree of protection against immune evasion caused by variations.
Xuan Ding, Feijun Zhao, Zhaoping Liu, Jiangchen Yao, Han Yu, Xiaohong Zhang   +5 more
openaire   +2 more sources

The porcine reproductive and respiratory syndrome [PDF]

, 1993
Albina, E., Benfield, D., Conzelmann, Karl-Klaus, Drew, T. W., Meulenberg, J. J. M., Murtaugh, M., Nelson, E. A., Thiel, Heinz-Jürgen, Wensvoort, G.   +8 more
core   +1 more source

"Original antigenic sin": A potential threat beyond the development of booster vaccination against novel SARS-CoV-2 variants. [PDF]

Infect Control Hosp Epidemiol, 2022
Noori M, Nejadghaderi SA, Rezaei N.
europepmc   +1 more source

Antigenic Imprinting Dominates Humoral Responses to New Variants of SARS-CoV-2 in a Hamster Model of COVID-19

Microorganisms
The emergence of SARS-CoV-2 variants escaping immunity challenges the efficacy of current vaccines. Here, we investigated humoral recall responses and vaccine-mediated protection in Syrian hamsters immunized with the third-generation Comirnaty® Omicron ...
Joran Degryse, Elke Maas, Ria Lassaunière, Katrien Geerts, Yana Kumpanenko, Birgit Weynand, Piet Maes, Johan Neyts, Hendrik Jan Thibaut, Yeranddy A. Alpizar, Kai Dallmeier   +10 more
doaj   +1 more source

What about the original antigenic sin of the humans versus SARS-CoV-2? [PDF]

Med Hypotheses, 2020
Roncati L, Palmieri B.
europepmc   +1 more source

Previous Humoral Immunity to the Endemic Seasonal Alphacoronaviruses NL63 and 229E Is Associated with Worse Clinical Outcome in COVID-19 and Suggests Original Antigenic Sin. [PDF]

Life (Basel), 2021
Focosi D, Genoni A, Lucenteforte E, Tillati S, Tamborini A, Spezia PG, Azzi L, Baj A, Maggi F.   +8 more
europepmc   +1 more source

Modeling original antigenic sin in dengue viral infection [PDF]

, 2017
Nikin-Beers, Ryan
core   +1 more source

Signatures of Original Antigenic Sin or protection following coronavirus imprinting in Syrian hamsters challenged with SARS-CoV-2 or variants

, 2023
Francis M, Jansen E, Yourkowski A, Selim A, Swan C, MacPhee B, Thivierge B, Buchanan R, Lavender K, Darbellay J, Rogers M, Lew J, Gerdts V, Falzarano D, Skowronski D, Sjaarda C, Kelvin A.   +16 more
europepmc   +1 more source