Results 31 to 40 of about 4,776,365 (127)
Antigenic variation in Trypanosoma brucei: joining the DOTs [PDF]
, 2008 African trypanosomes, such as <i>Trypanosoma brucei</i>, are protistan parasites that cause sleeping sickness. Though first described more than a century ago, trypanosomes remain a blight on the health of the human population and on the ...
Swiderski, Michal R. +11 more
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Advanced Science, Volume 13, Issue 48, 28 August 2026.This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang +12 more
wiley +1 more source
Protein Science, Volume 35, Issue 8, August 2026.Abstract The accurate prediction of antibody–antigen (AbAg) complexes is a key challenge for computational immunology, with applications in therapeutic antibody design and diagnostics. Current deep learning methods have the potential to generate high‐confidence AbAg structures.
Joakim Nøddeskov Clifford +1 more
wiley +1 more source
Le operazioni manuali di pulizia in cleanroom OAS [PDF]
, 2022 Il presente documento è stato elaborato da parte dei Responsabili della camera bianca in collaborazione con il Direttore di OAS Bologna ed elenca l’attenzione data alle procedure di cleaning, con particolare riguardo non solo alle norme esistenti ma ...
TERENZI, Luca, SCHIAVONE, Filomena
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Immune Dysregulation in Branched Chain Organic Acidemias
Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.ABSTRACT Organic acidemias (OAs) are a group of inherited disorders, most commonly caused by defects in mitochondrial enzymes involved in amino acid and fatty acid metabolism. While they characteristically present with metabolic and neurological crises, growing evidence reveals a significant burden of chronic immune dysregulation in some disorders and ...
Abdul L. Shakerdi +3 more
wiley +1 more source
Neuregulin‐1 Mitigates Kidney Injury in Humanized Sickle Cell Mice
The FASEB Journal, Volume 40, Issue 10, 31 May 2026.Compared with untreated sickle cell (HbSS) mice, neuregulin‐1 (NRG‐1) treatment reduced plasma heme, lactate dehydrogenase, and pro‐inflammatory cytokines while increasing the proportion of circulating F‐cells. NRG‐1 improved urinary biomarkers of kidney health, decreasing cystatin C and NGAL levels and increased renal repair markers clusterin and ...
William K. Agbozo +12 more
wiley +1 more source
Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract
American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik +3 more
wiley +1 more source
Tierra mía sin nombre, sin América... [PDF]
, 1999 Tierra mía sin nombre, sin América..
AsN, América sin nombre
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The determinants of "domestic" original sin in emerging market economies [PDF]
This paper explains why domestic debt composition in some emerging economies is risky. To this end, it carries out a systematic analysis of the determinants of the so-called domestic original sin, which refers to the inability of emerging economies to ...
Julien Reynaud, Arnaud Mehl
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MedComm, Volume 7, Issue 3, March 2026.This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng +8 more
wiley +1 more source