Results 101 to 110 of about 79,683,097 (270)

Otologic Presentation and Management of Allergic Ear Disorder in a Tropical Developing Country [PDF]

open access: yes, 2020
Background: Allergic manifestation in ear is a common unrecognized otologic disorder worldwide. This study aimed at determining the clinicoepidemiologic pattern and management of patients with allergic ear disorder.
Adegbiji, Waheed Atilade   +5 more
core  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

INCAP ABILITY OF FORMALIN BASED FIXA TIVE T O KILL MAGGOT IN MUTILA TED HUMAN CARRION [PDF]

open access: yes, 2015
Background: Embalming is a process used to temporarily preserve a human cadaver to forestall decomposi tion and make it suitable for di splay at funerals; thus, are agents that prevent autolysis and putrefaction.
Raji, M.O   +3 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Molossian Hound

open access: yes
Overall view, side view; Hellenistic realism extended to the expressive portrayal of animals as well as humans. Many bronze animal sculptures of this period are only known to us through Roman marble copies.
unknown (Ancient Roman sculptor, after Greek original)
core  

Communication Disorders among Children in a Developing Country, Nigeria [PDF]

open access: yes, 2019
Background: Communication disorders in children are an invisible disability posing challenges to otorhinolaryngologist in developing countries. The aim of this study was to determine the prevalence, sociodemographic features, aetiology, types of ...
Ali, Ahmed   +4 more
core  

Assessment of the Effects of Graded Doses of Polyphenolic-Rich Fraction of Garcinia kola Seeds on Pituitary–Testicular Axis of Male Wistar Rats [PDF]

open access: yes, 2017
This study evaluated the ameliorative and prophylactic effects of 2 different doses of polyphenolic-rich fraction of Garcinia kola (PPRFGk) seeds on the histology and hormones of pituitary–testicular axis of male Wistar rats.
Obuotor, Efere M.   +4 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Toxicological evaluation of Moringa oleifera Lam seeds and leaves in Wistar rats [PDF]

open access: yes, 2016
Miracle tree (Moringa oleifera) as it is popularly called, has been found useful both medicinally and economically. Its consumption both in the raw and as processed preparations has increased a great deal thus making the fast ...
Akintayo, Christopher Oloruntoba   +2 more
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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