Results 111 to 120 of about 5,181,809 (235)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Original Article--Evaluation of Radial Artery Anatomy With Various Anatomical Variants in Patients Undergoing Transradial Catheterization. [PDF]

J Saudi Heart Assoc
Desai N, Jain S, Parwani K, Vyas P, Sidatar Y.   +4 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Hip Abduction Strength Assessment and its Effect on Functional Outcome Following Hip Arthroplasty - Original Article. [PDF]

J Orthop Case Rep
Vardhan BV, Pradeep P, Raghavendran B, Thiyagarajan U, Ahmed MR.   +4 more
europepmc   +1 more source

Letter to the Editor on the original article: Lower prevalence of congenital cytomegalovirus infection in Portugal: possible impact of COVID-19 lockdown? [PDF]

Eur J Pediatr, 2022
Ríos-Barnés M, Fontalvo MA, Liñán N, Plana M, Moreno M, Esteva C, Muñoz-Almagro C, Noguera-Julian A, Alarcón A, CRIB Study team.   +9 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

3D analysis of smile transformation in patients with class III deformities following orthognathic surgery: a stereophotogrammetric study : Original Article. [PDF]

Clin Oral Investig
Enez A, Altıparmak N, Akdeniz BS, Akdeniz SS.   +3 more
europepmc   +1 more source

Original Article Phytotherapy in Adults With Recurrent Uncomplicated Cystitis. [PDF]

Dtsch Arztebl Int, 2022
Kranz J, Lackner J, Künzel U, Wagenlehner F, Schmidt S.   +4 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Incidence of Accessory Navicular Bone among the Indian Population - An Original Article. [PDF]

J Orthop Case Rep
Pawar P, Pawar R.
europepmc   +1 more source