Results 31 to 40 of about 1,438,384 (168)

UP TO DATE ANTIPLATELET THERAPY IN PATIENTS WITH HIGH RISK OF THROMBOTIC EVENTS AND REAL CLINICAL PRACTICE

Рациональная фармакотерапия в кардиологии, 2015
Aim. To assess the real rate of dual antiplatelet therapy (DAT, acetylsalicylic acid + clopidogrel) use in patients having appropriate indications according to current clinical guidelines and to study the possibility of prescription rate improvement by ...
S. Yu. Martsevich, V. P. Voronina, M. L. Ginzburg, N. P. Kutishenko, Yu. N. Polyanskaya, T. G. Kheliya, A. M. Malysheva, S. N. Tolpygina, V. S. Kutuzova, E. A. Gofman, A. D. Deev   +10 more
doaj   +1 more source

QUALITATIVE DRUG: WHAT SHOULD IT LOOK LIKE?

Рациональная фармакотерапия в кардиологии, 2016
Drug quality in modern market is discussed. There is an increase of a number of drugs that don’t meet to the quality requirements.Most of them are produced by Russian manufacturers, which number has also increased recently.
V. V. Iakusevich
doaj   +1 more source

Choosing a systemic antifungal agent for the treatment of vaginal candidiasis: original or generic fluconazole?

Медицинский совет, 2015
The article tells about the main guidelines for choosing a systemic antifungal agent containing fluconazole from those present on the Russian market of medicinal products. Results of comparing original and generic fluconazole medicines are demonstrated.
А. S. Dukhanin
doaj   +1 more source

Contrastive analysis on the safety of brand and generic nebivolol: a real-world pharmacovigilance study based on the FDA adverse event reporting system

Frontiers in Pharmacology
Background: The equivalence of generic drugs to their brand-name counterparts is a controversial issue. Current literature indicates disparities between the generic nebivolol (GN) and the brand nebivolol (BN).Aim: The study is designed to investigate the
Hongli Wang, Hongli Wang, Guizun Zhong, Guizun Zhong, Huanhuan Ji, Siqi Chen, Qinqin Xie, Zhengze Shen, Yuntao Jia   +8 more
doaj   +1 more source

MODERN PECULIARITIES OF MYOCARDIAL CYTOPROTECTION IN THERAPY OF ISHEMIC HEART DISEASE PATIENTS

Медицинский совет, 2016
Results of meta-analysis of more than 20 clinical studies of use of various dosages and schemes of indication of trimetazidine to stable ischemic heart disease patients allowed considering the daily dosage of trimetazidine 70 mg as a standard therapeutic
Z. M. SIZOVA, S .K. VLADIMIROV
doaj   +1 more source

COMPARISON OF ANTIPLATELET EFFECT AND SAFETY OF ORIGINAL DRUG «ASPIRIN CARDIO» AND GENERIC«ACECARDOL» IN PATIENTS WITH ARTERIAL HYPERTENSION 1-2 GRADE

Рациональная фармакотерапия в кардиологии, 2016
Aim. To compare antiplatelet effect of two acetylsalicylic acid medicines, Acecardol ("Synthesis Co. Ltd", Russia) and Aspirin cardio («Bayer AG», Germany), in patients with arterial hypertension (AH) 1-2 stage with increased risk of cardiovascular ...
N. A. Belolipetskiy, S. N. Tolpygina, O. А. Litinskaya, V. G. Belolipetskaya, S. Yu. Martsevich   +4 more
doaj   +1 more source

CLINICAL AND PHARMACOKINETIC EQUIVALENCE OF ORIGINAL AND GENERIC AMLODIPINE IN PATIENTS WITH MILD-TO-MODERATE ARTERIAL HYPERTENSION

Рациональная фармакотерапия в кардиологии, 2015
Aim. To study clinical equivalence of two amlodipines under the control of their plasma levels and evaluate their pharmacoeconomical efficacy in patients with arterial hypertension (AH).Material and methods. 31 patient with AH were included in the study (
N. A. Belolipetskiy, S. N. Tolpygina, J. B. Zverkov, V. V. Pisarev, I. E. Koltunov, V. G. Belolipetskaya, S. J. Martsevich   +6 more
doaj   +1 more source

Comparative Study of Drug Efficacy and Drug Additives between Generic Drugs and Original Drugs

YAKUGAKU ZASSHI, 2007
In the present study, we tested three kinds of sleeping drugs, consisting mainly of triazolam, brotizolam, and flunitrazepam, to compare the drug efficacy of generic drugs with that of original drugs. After these drugs were administered orally to mice, drug efficacy was evaluated in terms of ambulation, onset time of sleep, and duration of sleep in the
Hiromi, Katoh, Michiko, Yoshii, Koichiro, Ozawa   +2 more
openaire   +3 more sources

ASSESSMENT OF THERAPEUTICAL EQUIVALENCY OF ORIGINAL AND GENERIC INDAPAMIDE IN HYPERTENSIVE PATIENTS BY RANDOMIZED CROSS-OVER STUDY

Рациональная фармакотерапия в кардиологии, 2015
Aim. To develop a protocol for comparison of efficacy and safety of original drugs with generic ones and to apply this protocol for comparison of generic indapamide (Indap) with original indapamide in two presentations: short acting (Arifon) and long ...
N. P. Kutishenko, V. V. Yakusevich, A. D. Deev, S. Y. Martsevich   +3 more
doaj   +1 more source

A COMPARATIVE STUDY OF THE EFFICACY AND TOLERABILITY OF ORIGINAL AND GENERIC BISOPROLOL IN MONOTHERAPY OR IN COMBINATION WITH S-AMLODIPINE AND INDAPAMIDE IN PATIENTS WITH ARTERIAL HYPERTENSION 1-2 DEGREES. RESULTS OF THE CLINICAL RANDOMIZED CROSSOVER STUDY

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study the clinical equivalence of original and generic drugs of bisoprolol in patients with arterial hypertension (HT) 1-2 degrees according to protocol recommended by the Society of Cardiology of the Russian Federation for comparative studies ...
S. Yu. Martsevich, S. N. Tolpygina, V. P. Voronina, O. V. Lerman, Yu. V. Lukina, N. A. Dmitrieva, I. V. Vashurina   +6 more
doaj   +1 more source