Results 41 to 50 of about 2,153,835 (285)

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk, Amanda Cristina Meneguetti Berti, Bárbara Braga Vieira Marques, Victoria Simões Bernardo, Flaviene Felix Torres, Ingrid Souza Dias, Vanessa da Silveira Ramos de Castro, Gabriela Alves Bernardino, Danilo Grünig Humberto da Silva, Edis Belini‐Júnior   +9 more
wiley   +1 more source

Shaped in Iniquity or Knit Together by God? An Inquiry into the Psalmist’s Understanding of Humanity’s Sinful Nature

Old Testament Essays
Several authors have employed Ps 51:5 as a foundation for teaching the doctrine of original sin, which portrays the complete depravity of human nature (cf. Ps 58:3).
Melak Alemayehu Tsegaw
doaj   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Original Sin, the Fall, and Epistemic Self-Trust

TheoLogica, 2018
In this paper, I argue that no strong doctrine of the Fall can undermine the propriety of epistemic self-trust. My argument proceeds by introducing a common type of philosophical methodology, known as reflective equilibrium.
Jonathan C. Rutledge
doaj   +1 more source

THE THEOLOGICAL PROBLEM WITH EVOLUTION

Zygon, 2021
This article explores hamartiological questions at the interface of evolutionary biology and theology. Such questions include the problem of evil, the possibility of a historical fall, and the meaning of human sinfulness in light of biology.
doaj   +2 more sources

Original Sin and Judicial Independence: Providing Accountability for Justices [PDF]

, 2009
The independence of the judiciary is an enduring and defining objective of the legal profession. Law depends on judges to observe and enforce it. To secure such virtuous judges, they must be protected from retaliation by those who disapprove their ...
Carrington, Paul D., Cramton, Roger C.
core   +3 more sources

Probing the neutrino mass hierarchy and the 13-mixing with supernovae [PDF]

, 2003
We consider in details the effects of the 13-mixing (sin^2 theta_{13}) and of the type of mass hierarchy/ordering (sign[ Delta m^2_{13}]) on neutrino signals from the gravitational collapses of stars.
Akhmedov E K, Alexei Yu Smirnov, Arneodo F (ICARUS collaboration), Bahcall J N, Barbieri R, Barger V, Barger V, Beacom J F, Beacom J F, Boehm F, Cecilia Lunardini, Clayton D D, Cline D B, de Holanda P C, Dighe A S, Dutta G, Dutta G, Dzewonski A M, Fogli G L, Friedland A, Janka H T, Janka H T, Jegerlehner B, Jung C K, Kachelriess M, Kachelriess M, Keil M T, Kuo T K, Kuo T K, Lunardini C, Lunardini C, Mikheev S P, Minakata H, Nunokawa H, Raffelt G G, Schirato R C, Shiozawa M, Strumia A, Super-Kamiokande Collaboration, Takahashi K, Takahashi K, TITAND Working Group Collaboration, Vagins M, Vogel P, Waltham C   +44 more
core   +3 more sources

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Heterotypic Neuraminidase Antibodies Against Different A(H1N1) Strains are Elicited after Seasonal Influenza Vaccination

Vaccines, 2019
Neuraminidase (NA) content is not standardized in current seasonal influenza vaccines; neither anti-NA antibodies (anti-NA Abs) are measured nor is it well-defined as a correlate of humoral protection. In this work, the presence of NA1 antibodies against
Jose Manuel Mendez-Legaza, Raúl Ortiz de Lejarazu, Ivan Sanz   +2 more
doaj   +1 more source