Results 51 to 60 of about 2,153,835 (285)
SARS-CoV-2 vaccination in the context of original antigenic sin
Human Vaccines & Immunotherapeutics, 2022 Immunological memory is the ability of the adaptive immune system to ensure a persistent protective effect after immunization. However, it can also be a limitation to building a sufficient level of protective antibodies specific to new mutations of the ...
Marek Petráš, Ivana Králová Lesná
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra +3 more
wiley +1 more source
Meta-Analysis of Human Nature through the Comparative Comparison of Judgmental Concepts in the Thought of Allameh Tabatabai and Augustine [PDF]
پژوهشنامه کلام تطبیقی شیعهHuman nature is one of the most important propositions of belief, which has become the starting point of contemporary insights about man, and it will be influential in the context of any school of thought that is translated.
Mohammad Esmaeil Abdollahi
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost +10 more
wiley +1 more source
The Formation of the Teaching on Original Sin from the First Through the Fifth Centuries
Богословські роздуми: Східноєвропейський журнал богословʼя, 2016 This article surveys the sources, appearance, development, and establishment of the teaching on original sin as dogma. The material is presented in historical sequence and encompasses the period from the first to the fifth centuries when the church’s ...
Oleg BUDAKOV
doaj
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack +39 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Original Sin, Preterition, and its Implications for Evangelization
Perichoresis: The Theological Journal of Emanuel University, 2020 In this paper, I examine the four elements—universal sinfulness, natural sinfulness, inherited sinfulness, and Adamic sinfulness—of the doctrine of original sin in both the Reformed confessions, with particular attention to the Canons of Dort, and the ...
Echeverria Eduardo J.
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source