Results 131 to 140 of about 1,434,799 (290)

Primitive Oligomeric RNAs at the Origins of Life on Earth. [PDF]

Int J Mol Sci, 2023
Demongeot J, Thellier M.
europepmc   +1 more source

10-02 "Care Ethics and Markets: A View from Feminist Economics" [PDF]

It is common to think of care ethics and justice ethics as being opposed to each other, and also to think of economic life as being opposed to social life.
Julie A. Nelson
core  

Environment and Obesity in the National Children\u27s Study [PDF]

, 2009
Objective: In this review we describe the approach taken by the National Children’s Study (NCS), a 21-year prospective study of 100,000 American children, to understanding the role of environmental factors in the development of obesity.
Carrel, Aaron L, Cronk, Christine E., Durkin, Maureen S., Gall, Elizabeth A, Gillman, Matthew W, Hewitt, Jeanne B, Landrigan, Philip J, Schoeller, Dale A, Trasande, Leonardo, Weiss, Marianne E.   +9 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

DNA and the origins of life in micaceous clay. [PDF]

Biophys J, 2022
Hansma HG.
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Marine phosphate availability and the chemical origins of life on Earth. [PDF]

Nat Commun, 2022
Brady MP, Tostevin R, Tosca NJ.
europepmc   +1 more source

The Role of Early-Life Conditions in the Cognitive Decline due to Adverse Events Later in Life [PDF]

Cognitive functioning of elderly individuals may be affected by events such as the loss of a (grand)child or partner or the onset of a serious chronic condition, and by negative economic shocks such as job loss or the reduction of pension benefits. It is
Deeg, Dorly J. H., Lindeboom, Maarten, Portrait, France, van den Berg, Gerard J.   +3 more
core  

Origins of Purpose in Life: Refining our Understanding of a Life Well Lived [PDF]

, 2009
Purpose can be characterized as a central, self-organizing life aim. Central in that when present, purpose is a predominant theme of a person’s identity.
Patrick E. McKnight, Todd B. Kashdan
core   +1 more source