Results 121 to 130 of about 167,907,926 (289)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2017 Conceiving the process of biogenesis as the evolutionary development of highly dynamic and integrated protocell populations provides the most appropriate framework to address the difficult problem of how prebiotic chemistry bridged the gap to full ...
Ben Shirt-Ediss +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
15th International Conference on Biosystems Engineering 2025 : Book of Abstracts : May 7-9 2025 in Tartu, Estonia [PDF]
Book of Abstracts. 15th International Conference on Biosystems Engineering 2025, May 7–9, 2025 Tartu, Estonia.
Estonian University of Life Sciences
core +1 more source
Thermodynamic origin of life [PDF]
, 2010 Abstract. Understanding the thermodynamic function of life may shed light on its origin. Life, as are all irreversible processes, is contingent on entropy production. Entropy production is a measure of the rate of the tendency of Nature to explore available microstates.
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
14th International Conference on Biosystems Engineering 2024 : Book of Abstracts : May 8-10 2024 in Tartu, Estonia [PDF]
Book of Abstracts. 14th International Conference on Biosystems Engineering 2024, May 8–10, 2024 Tartu, Estonia.
Estonian University of Life Sciences
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
LIFE-COURSE EPIDEMIOLOGY: DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE
, 2017 LIFE-COURSE EPIDEMIOLOGY: DEVELOPMENTAL ORIGINS OF HEALTH AND ...
Natalie Hyde (13074153)
core
Origins of life: first came evolutionary dynamics. [PDF]
QRB Discov, 2023 Kocher C, Dill KA.
europepmc +1 more source