Life’s Late Digital Revolution and Why It Matters for the Study of the Origins of Life [PDF]
Life, 2017 The information contained in life exists in two forms, analog and digital. Analog information is manifest mainly in the differing concentrations of chemicals that get passed from generation to generation and can vary from cell to cell.
David A. Baum, Niles Lehman
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Membraneless polyester microdroplets as primordial compartments at the origins of life [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance The prebiotic milieu was likely heterogeneous, consisting of a large number of chemicals and their associated reactions, including those not only of biological compounds, but also nonbiological compounds.
Tony Jia, Rehana Afrin, Tomohiro Usui
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Chance, necessity and the origins of life: a physical sciences perspective [PDF]
Philosophical Transactions Series A, Mathematical, Physical, and Engineering Sciences, 2017 Earth's 4.5-billion-year history has witnessed a complex sequence of high-probability chemical and physical processes, as well as ‘frozen accidents’.
Robert Hazen
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L-form bacteria, chronic diseases and the origins of life [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2016 The peptidoglycan cell wall is widely conserved across the bacterial domain, suggesting that it appeared early in the evolution of bacteria. It is normally essential but under certain conditions wall-deficient or ‘L-form’ bacteria can be isolated.
Katarzyna Mickiewicz +2 more
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Evolution at the Origins of Life? [PDF]
LifeThe role of evolutionary theory at the origin of life is an extensively debated topic. The origin and early development of life is usually separated into a prebiotic phase and a protocellular phase, ultimately leading to the Last Universal Common ...
Andreas Kirschning +2 more
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Re-conceptualizing the origins of life [PDF]
Philosophical Transactions Series A, Mathematical, Physical, and Engineering Sciences, 2017 Sara Walker
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Alternative Pathways in Astrobiology: Reviewing and Synthesizing Contingency and Non-Biomolecular Origins of Terrestrial and Extraterrestrial Life [PDF]
LifeThe pursuit of understanding the origins of life (OoL) on and off Earth and the search for extraterrestrial life (ET) are central aspects of astrobiology.
Kuhan Chandru +2 more
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Origins of Life: The Protein Folding Problem all over again? [PDF]
Proc Natl Acad Sci U S AHow did specific useful protein sequences arise from simpler molecules at the origin of life? This seemingly needle-in-a-haystack problem has remarkably close resemblance to the old Protein Folding Problem, for which the solution is now known from ...
Kocher CD, Dill KA.
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Prebiotic chemistry and origins of life research with atomistic computer simulations
Physics of Life Reviews, 2020 Research in origins of life is an intrinsically multi-disciplinary field, aimed at finding answers to the formidably complex problem of understanding the emergence of life from the modern versions of Charles Darwin's celebrated "primordial soup".
Andrea Pérez-Villa +2 more
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Sequencing the origins of life [PDF]
BBA Advances, 2022 One goal of origins of life research is to understand how primitive informational and catalytic biopolymers emerged and evolved. Recently, a number of sequencing techniques have been applied to analysis of replicating and evolving primitive biopolymer ...
Tony Z. Jia +2 more
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