Results 41 to 50 of about 167,907,926 (289)

Prebiotic competition and evolution in self-replicating polynucleotides can explain the properties of DNA/RNA in modern living systems

open access: yesBMC Evolutionary Biology, 2020
Background We hypothesize prebiotic evolution of self-replicating macro-molecules (Alberts, Molecular biology of the cell, 2015; Orgel, Crit Rev Biochem Mol Biol 39:99-123, 2004; Hud, Nat Commun 9:5171) favoured the constituent nucleotides and ...
Hemachander Subramanian   +2 more
doaj   +1 more source

The building blocks and origins of life

open access: yesHTS Teologiese Studies/Theological Studies, 2020
The building blocks and origins of life have fascinated scientists since the earliest of times. What is required for life to work in terms of building blocks?
Dirk U. Bellstedt
doaj   +1 more source

Chair of landscape architecture : Estonian University of Life Sciences [PDF]

open access: yes, 2018
BookWelcome to the chair of Landscape Architecture at the Estonian University of Life Sciences. This book has been prepared as an introduction to our chair and should give you an insight into our teaching programme and examples of students’ works ...
Estonian University of Life Sciences. Chair of Landscape Architecture
core   +1 more source

Degradation, Osmosis and the Emergence of Basic Functionalities in Abiotic Synthetic Life-like Chemical Systems

open access: yesLife
Autonomous and interconnected multiscale out-of-equilibrium processes, including chemical and physical feedbacks, occur at the micron and lower scales during the heterotrophic synthesis of simple abiotic protocells, such as the ones developed in our ...
Chenyu Lin, Juan Pérez-Mercader
doaj   +1 more source

Prospective Cohort Study of Emergency Department Visit Frequency and Diagnoses Before and During COVID-19 Pandemic in Urban, Low-Income, US- and Foreign-Born Mothers in Boston, MA

open access: yesWestern Journal of Emergency Medicine, 2023
Background: The coronavirus 2019 (COVID-19) pandemic fundamentally changed how populations interface with the healthcare system. Despite historical spikes in US mortality during the pandemic, emergency department (ED) visits were paradoxically low.
Valerie Osula   +9 more
doaj   +1 more source

Systems Analysis for Peptide Systems Chemistry

open access: yesLife, 2019
Living systems employ both covalent chemistry and physical assembly to achieve complex behaviors. The emerging field of systems chemistry, inspired by these biological systems, attempts to construct and analyze systems that are simpler than biology ...
Martha A. Grover   +2 more
doaj   +1 more source

Transitioning to DNA genomes in an RNA world

open access: yeseLife, 2017
The unexpected ability of an RNA polymerase ribozyme to copy RNA into DNA has ramifications for understanding how DNA genomes evolved.
Razvan Cojocaru, Peter J Unrau
doaj   +1 more source

Prebiotic Synthesis of Aspartate Using Life’s Metabolism as a Guide

open access: yesLife, 2023
A protometabolic approach to the origins of life assumes that the conserved biochemistry of metabolism has direct continuity with prebiotic chemistry. One of the most important amino acids in modern biology is aspartic acid, serving as a nodal metabolite
Stuart A. Harrison   +3 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Evidence of Late Miocene Peri-Tibetan Aridification From the Oldest Asian Species of Sandgrouse (Aves: Pteroclidae)

open access: yesFrontiers in Ecology and Evolution, 2020
The partial skeleton of a new extinct taxon, Linxiavis inaquosus, from the Liushu Formation (6–9 Ma) at the edge of the Tibetan Plateau in Gansu Province, China is the most substantial known fossil record of sandgrouse (Pteroclidae).
Zhiheng Li   +8 more
doaj   +1 more source

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