Results 51 to 60 of about 1,434,799 (290)

Transitioning to DNA genomes in an RNA world

eLife, 2017
The unexpected ability of an RNA polymerase ribozyme to copy RNA into DNA has ramifications for understanding how DNA genomes evolved.
Razvan Cojocaru, Peter J Unrau
doaj   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi, Paula D. Robinson, Shana Jacobs, L. Lee Dupuis, the International Pediatric Dexamethasone Panel, Sameer Bakhshi, Tiene Bauters, Eva Brack, Simone Cesaro, Claire Fosbrook, Jason Freedman, Tamara MacDonald, Eloise Neumann, Venkatraman Radhakrishnan, Rod Rassekh, Florian Slimano, Johnathan Soggee, Joel Thompson, Marianne van de Wetering, Milena Villarroel, Jasper Wong   +20 more
wiley   +1 more source

Human prestige psychology can promote adaptive inequality in social influence

Nature Communications
Human hunter-gatherer groups were commonly thought to be broadly egalitarian, with increasingly formal hierarchical social structures hypothesized to spread following the introduction of agriculture.
Thomas J. H. Morgan, Robin Watson, Hillary L. Lenfesty, Charlotte O. Brand   +3 more
doaj   +1 more source

THE PROTOBIOLOGICAL THEORY OF CEILINGS AND FLOORS, OR CHEMICAL EVOLUTION AS A PLANETARY PROCESS [PDF]

Filozofia i Nauka
The article presents a modern protobiological theory based on the classical archetype. It connects the issues of origins of life with the theory of the hierarchy of matter and recognizes that error correction occurs within hierarchical and dynamic living
Alicja Kubica
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Airway specific deregulation of asthma-related serpins impairs tracheal architecture and oxygenation in D. melanogaster

Scientific Reports
Serine proteases are important regulators of airway epithelial homeostasis. Altered serum or cellular levels of two serpins, Scca1 and Spink5, have been described for airway diseases but their function beyond antiproteolytic activity is insufficiently ...
Birte Ehrhardt, Hanna Angstmann, Beate Höschler, Draginja Kovacevic, Barbara Hammer, Thomas Roeder, Klaus F. Rabe, Christina Wagner, Karin Uliczka, Susanne Krauss-Etschmann   +9 more
doaj   +1 more source

Bioenergetics and Life's Origins [PDF]

Cold Spring Harbor Perspectives in Biology, 2010
Bioenergetics is central to our understanding of living systems, yet has attracted relatively little attention in origins of life research. This article focuses on energy resources available to drive primitive metabolism and the synthesis of polymers that could be incorporated into molecular systems having properties associated with the living state ...
David, Deamer, Arthur L, Weber
openaire   +2 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

On the Role of ⁴⁰K in the Origin of Terrestrial Life

Life, 2022
The abundance and biological role of potassium suggest that its unstable nuclide was present in all stages of terrestrial biogenesis. With its enhanced isotopic ratio in the Archean eon, 40K may have contributed to the special, perhaps unique, biogenetic
Giovanni Vladilo
doaj   +1 more source