Results 61 to 70 of about 1,434,799 (290)

Life at the edge: Complexity and criticality in biological function [PDF]

open access: yes, 2018
Why life is complex and - most importantly - what is the origin of the over abundance of complexity in nature? This is a fundamental scientific question which, paraphrasing the late Per Bak, “is screaming to be answered but seldom is even being asked ...
Chialvo, Dante Renato
core   +2 more sources

Thermodynamics and the origin of life

open access: yesCanadian Journal of Physics, 2022
Modern developments in nonequilibrium thermodynamics have significant implications for the origins of life. The reasons for this are closely related to a generalized version of the second law of thermodynamics recently found for entropy production during irreversible evolution of a given system such as self-replicating RNA.
openaire   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

The origin of compression influences geometric instabilities in bilayers [PDF]

open access: yes, 2018
Geometric instabilities in bilayered structures control the surface morphology in a wide range of biological and technical systems. Depending on the application, different mechanisms induce compressive stresses in the bilayer.
Andres, Sebastian   +2 more
core   +1 more source

Metabolic, Replication and Genomic Category of Systems in Biology, Bioinformatics and Medicine [PDF]

open access: yes, 2012
Metabolic-repair models, or (M,R)-systems were introduced in Relational Biology by Robert Rosen. Subsequently, Rosen represented such (M,R)-systems (or simply MRs)in terms of categories of sets, deliberately selected without any structure other than the ...
I. C. Baianu
core   +1 more source

Commentary: The History of Neurosurgery at Albany Medical College and Albany Medical Center Hospital, Albany, New York. [PDF]

open access: yes, 2019
The origins of the Department of Neurosurgery at Albany Medical College closely parallel the development of early America and the establishment of modern health care.The tales of Washington Irving, the works of the Hudson River School of painters, and ...
Adedamola Adepoju   +7 more
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Mechanical Energy before Chemical Energy at the Origins of Life?

open access: yesSci, 2020
Mechanical forces and mechanical energy are prevalent in living cells. This may be because mechanical forces and mechanical energy preceded chemical energy at life’s origins.
Helen Greenwood Hansma
doaj   +1 more source

Sources of Nitrogen-, Sulfur-, and Phosphorus-Containing Feedstocks for Prebiotic Chemistry in the Planetary Environment

open access: yesLife, 2022
Biochemistry on Earth makes use of the key elements carbon, hydrogen, oxygen, nitrogen, phosphorus, and sulfur (or CHONPS). Chemically accessible molecules containing these key elements would presumably have been necessary for prebiotic chemistry and the
Zoe R. Todd
doaj   +1 more source

Category of Metabolic-Replication Systems\ud in Biology and Medicine [PDF]

open access: yes, 2012
Metabolic-repair models, or (M,R)-systems were introduced in Relational Biology by Robert Rosen. Subsequently, Rosen represented such (M,R)-systems (or simply MRs) in terms of categories of sets, deliberately selected without any structure other than the
Baianu, Prof.Dr. I.C.
core  

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