Results 81 to 90 of about 361,547 (333)

Lifeness signatures and the roots of the tree of life [PDF]

open access: yes, 2010
Do trees of life have roots? What do these roots look like? In this contribution, I argue that research on the origins of life might offer glimpses on the topology of these very roots.
Malaterre, Christophe
core   +1 more source

Degradation, Osmosis and the Emergence of Basic Functionalities in Abiotic Synthetic Life-like Chemical Systems

open access: yesLife
Autonomous and interconnected multiscale out-of-equilibrium processes, including chemical and physical feedbacks, occur at the micron and lower scales during the heterotrophic synthesis of simple abiotic protocells, such as the ones developed in our ...
Chenyu Lin, Juan Pérez-Mercader
doaj   +1 more source

Transitioning to DNA genomes in an RNA world

open access: yeseLife, 2017
The unexpected ability of an RNA polymerase ribozyme to copy RNA into DNA has ramifications for understanding how DNA genomes evolved.
Razvan Cojocaru, Peter J Unrau
doaj   +1 more source

Distinguishing Biotic vs. Abiotic Origins of ‘Bio’signatures: Clues from Messy Prebiotic Chemistry for Detection of Life in the Universe [PDF]

open access: yes, 2023
It is not a stretch to say that the search for extraterrestrial life is possibly the biggest of the cosmic endeavors that humankind has embarked upon.
Niraja V. Bapat, Sudha Rajamani
core   +1 more source

Evidence of Late Miocene Peri-Tibetan Aridification From the Oldest Asian Species of Sandgrouse (Aves: Pteroclidae)

open access: yesFrontiers in Ecology and Evolution, 2020
The partial skeleton of a new extinct taxon, Linxiavis inaquosus, from the Liushu Formation (6–9 Ma) at the edge of the Tibetan Plateau in Gansu Province, China is the most substantial known fossil record of sandgrouse (Pteroclidae).
Zhiheng Li   +8 more
doaj   +1 more source

Prebiotic Synthesis of Aspartate Using Life’s Metabolism as a Guide

open access: yesLife, 2023
A protometabolic approach to the origins of life assumes that the conserved biochemistry of metabolism has direct continuity with prebiotic chemistry. One of the most important amino acids in modern biology is aspartic acid, serving as a nodal metabolite
Stuart A. Harrison   +3 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Origins of Life Research: A Bibliometric Approach [PDF]

open access: yes, 2018
This study explores the collaborative nature and interdisciplinarity of the origin(s) of life (OoL)research community. Although OoL research isone of the oldest topics inphilosophy, religion, and science; to date there has been noreview of the field ...
Taşkın, Zehra
core  

Nonenzymatic Metabolic Reactions and Life's Origins.

open access: yesChemical Reviews, 2020
Prebiotic chemistry aims to explain how the biochemistry of life as we know it came to be. Most efforts in this area have focused on provisioning compounds of importance to life by multistep synthetic routes that do not resemble biochemistry.
K. B. Muchowska, S. Varma, Joseph Moran
semanticscholar   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks   +5 more
wiley   +1 more source

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