Results 71 to 80 of about 2,974 (211)
Antibiotic Resistance: A Genetic and Physiological Perspective
MedComm, Volume 6, Issue 11, November 2025.The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy +9 more
wiley +1 more source
Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus [PDF]
, 2014 Ramoplanin is an actinomycetes-derived antibiotic with broad-spectrum activity against Gram-positive bacteria that has been evaluated in clinical trials for the treatment of gastrointestinal vancomycin-resistant enterococci (VRE) and Clostridium ...
Butler, Mark S. +4 more
core +1 more source
PLoS ONE, 2021 ObjectiveTo compare between current evidence of novel glycopeptides against vancomycin for the treatment of gram-positive bacterial infections.MethodologyA systematic review and meta-analysis was done.
Wissal Jame +2 more
doaj +1 more source
New Antimicrobials for Gram-Positive Sustained Infections: A Comprehensive Guide for Clinicians
Pharmaceuticals, 2023 Antibiotic resistance is a public health problem with increasingly alarming data being reported. Gram-positive bacteria are among the protagonists of severe nosocomial and community infections.
Davide Carcione +13 more
doaj +1 more source
Review on bibliography related to antimicrobials [PDF]
, 2017 In this report, a bibliographic research has been done in the field of antimicrobials.In this report, a bibliographic research has been done in the field of antimicrobials.
Torrent Burgués, Juan
core +1 more source
Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics [PDF]
, 2012 Bacteria have shown a remarkable ability to overcome drug therapy if there is a failure to achieve sustained bactericidal concentration or if there is a reduction in activity in situ.
Farokhzad, Omid C. +5 more
core +1 more source
Hypericin enhances β-lactam antibiotics activity by inhibiting sarA expression in methicillin-resistant Staphylococcus aureus. [PDF]
, 2019 Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection.
Jiang, Jiandong +8 more
core
Uniformity of Glycyl Bridge Lengths in the Mature Cell Walls of Fem Mutants of Methicillin-Resistant Staphylococcus aureus [PDF]
, 2013 Peptidoglycan (PG) composition in intact cells of methicillin-resistant Staphylococcus aureus (MRSA) and its isogenic Fem mutants has been characterized by measuring the glycine content of PG bridge structures by solid-state nuclear magnetic resonance ...
Chen, Jiawei +4 more
core +2 more sources
Mechanism of action of oritavancin and related glycopeptide antibiotics [PDF]
FEMS Microbiology Reviews, 2003 Oritavancin (LY333328) is a semisynthetic glycopeptide antibiotic having excellent bactericidal activity against glycopeptide-susceptible and -resistant Gram-positive bacteria. Oritavancin is the N-alkyl-p-chlorophenylbenzyl derivative of chloroeremomycin (LY264826) and is currently in phase III clinical trials for use in Gram-positive infections ...
Norris E, Allen, Thalia I, Nicas
openaire +2 more sources
Protein Science, Volume 34, Issue 6, June 2025.Abstract Since the emergence of SARS‐CoV‐2 at the end of 2019, the virus has caused significant global health and economic disruptions. Despite the rapid development of antiviral vaccines and some approved treatments such as remdesivir and paxlovid, effective antiviral pharmacological treatments for COVID‐19 patients remain limited. This study explores
Spyros D. Chatziefthymiou +13 more
wiley +1 more source