Results 61 to 70 of about 2,974 (211)

Cost-minimisation analysis of oritavancin for the treatment of acute bacterial skin and skin structure infections from a United Kingdom perspective [PDF]

, 2022
BACKGROUND: Early discharge (ED) from hospital and outpatient parenteral antibiotic therapy (OPAT) are effective approaches for the management of a range of infections, including acute bacterial skin and skin structure infections (ABSSSI).
Falla, Edel, Mantopoulos, Theo, Nathwani, Dilip, Vlachaki, Ioanna, Zinzi, Daniela   +4 more
core   +2 more sources

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Continued Dosing of Oritavancin for Complicated Gram-Positive Infections [PDF]

Federal Practitioner, 2020
Several retrospective and cohort analyses have suggested that continued dosing of oritavancin is both safe and efficacious for complicated Gram-positive infections, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci.
Jodi, Meyer, Paul, Lata, Susanne, Barnett   +2 more
openaire   +2 more sources

Evaluating the Effect of Therapeutic Antibiotics in Prosthetic Joint Infections Culturing: A Narrative Review

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims One of the important complications of knee and hip replacement arthroplasty is prosthetic joint infection (PJI), which is usually accompanied by negative culture that leads to severe consequences compared to positive ones. This study aims to evaluate the arbitrary use or mistreatment of antibiotics for therapeutic purposes ...
Moein Zangiabadian, Mehrdad Jafari Tadi, Fateme Yousefimoghaddam, Ali Zangiabadian, Amir Ghaffari Jolfayi   +4 more
wiley   +1 more source

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection

Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon, Victoria R. Wong, Samuelson E. Osifo, Timothy Edwards, Himanshu Rao, Jewelia Rempuszewski, Andrew J. Frear, Shaan Sadhwani, Neel B. Shah, Kenneth L. Urish   +9 more
wiley   +1 more source

Antibacterial activity of recently approved antibiotics against methicillin-resistant Staphylococcus aureus (MRSA) strains: A systematic review and meta-analysis

Annals of Clinical Microbiology and Antimicrobials, 2022
Background Methicillin-resistant Staphylococcus aureus (MRSA) infections are considered an important public health problem, and treatment options are limited.
Fei Liu, Sajad Rajabi, Chunhua Shi, Ghazale Afifirad, Nazanin Omidi, Ebrahim Kouhsari, Saeed Khoshnood, Khalil Azizian   +7 more
doaj   +1 more source

Antibiotikaresistenzen gezielt überwinden [PDF]

, 2016
Neue Strategien zur Bekämpfung von Antibiotikaresistenzen zu finden, ist eine der grössten globalen Herausforderungen für die Gesundheitssysteme. In den letzten Jahrzehnten gab es eine drastische Zunahme an humanpathogenen Bakterien, die resistent gegen ...
Chellat, Mathieu F., Raguž, Luka, Riedl, Rainer   +2 more
core   +1 more source

Vancomycin‐Functionalized Nanodelivery Systems for Antibacterial Tissue Engineering Scaffolds

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review consolidates recent advancements in VAN nanoformulations, critically evaluating their design principles, release mechanisms, and efficacy profiles against resistant Gram‐positive pathogens. While promising in vitro and in vivo results have been demonstrated, the clinicaltranslation of these technologies necessitates further rigorous ...
Nima Beheshtizadeh, Mahsa Mohammadzadeh, Amir Abbas Seraji, Ali Pirsadeghi, Elham Zendedel, Maliheh Gharibshahian   +5 more
wiley   +1 more source

Glycopeptide Hypersensitivity and Adverse Reactions

Pharmacy, 2020
Glycopeptides, such as vancomycin and teicoplanin, are primarily used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections, such as cellulitis, endocarditis, meningitis, pneumonia, and septicemia, and are some of the most ...
Vanthida Huang, Nicola A. Clayton, Kimberly H. Welker   +2 more
doaj   +1 more source

Pathogens of skin and skin-structure infections in the UK and their susceptibility to antibiotics, including ceftaroline [PDF]

, 2015
Objectives: Bacterial skin and skin-structure infections (SSSIs) are frequent settings for antibiotic use. We surveyed their UK aetiology and pathogen susceptibility, including susceptibility to ceftaroline.
James, Dorothy, Kearns, Angela M, Livermore, David, Mushtaq, Shazad, Warner, Marina, Woodford, Neil   +5 more
core   +1 more source