Consolidating Russia and Eurasia Antibiotic Resistance Data for 1992–2014 Using Search Engine [PDF]
, 2016 Background: The World Health Organization recognizes the antibiotic resistance problem as a major health threat in the 21st century. The paper describes an effort to fight it undertaken at the verge of two industries - healthcare and Data Science. One of
Alexander Bedenkov +4 more
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Assessment of Oritavancin Serum Protein Binding across Species [PDF]
Antimicrobial Agents and Chemotherapy, 2010 ABSTRACT Biophysical methods to study the binding of oritavancin, a lipoglycopeptide, to serum protein are confounded by nonspecific drug adsorption to labware surfaces. We assessed oritavancin binding to serum from mouse, rat, dog, and human by a microbiological growth-based method under conditions that allow near-quantitative drug recovery.
Francis F, Arhin +6 more
openaire +2 more sources
Real-World Use of Oritavancin for the Treatment of Osteomyelitis
Drugs - Real World Outcomes, 2020 Osteomyelitis is a difficult-to-treat disease that can require both surgical debridement and a prolonged course of antimicrobial therapy. Current standard of care for the antimicrobial treatment of osteomyelitis is fraught with multiple challenges and ...
Patrick J. Scoble +2 more
doaj +1 more source
Assessment of Minimum Inhibitory Concentrations of Telavancin by Revised Broth Microdilution Method in Phase 3 Hospital-Acquired Pneumonia/Ventilator-Associated Pneumonia Clinical Isolates [PDF]
, 2016 INTRODUCTION: The broth microdilution method (BMD) for testing telavancin minimum inhibitory concentrations (MICs) was revised (rBMD) in 2014 to improve the accuracy, precision, and reproducibility of the testing method.
Gordon Ralph Corey +4 more
core +1 more source
Evaluation of Oritavancin Use at a Community Hospital [PDF]
Hospital Pharmacy, 2017 Background: Oritavancin is a lipoglycopeptide antibiotic indicated for the treatment of acute bacterial skin and soft tissue infections. The prolonged half-life of this agent allows for a course of therapy to be completed with a single dose. Oritavancin was added to our formulary as an option for treatment of acute bacterial skin and soft tissue ...
Daniel, Co +2 more
openaire +2 more sources
Novel and emerging antimicrobial strategies in the management of oral infections
Periodontology 2000, EarlyView.Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley +1 more source
Distinct Effectiveness of Oritavancin against Tolerance-Induced Staphylococcus aureus
Antibiotics, 2020 Within a sufficiently large bacterial population, some members will naturally adopt an alternate, metabolically-active state that favors small molecule synthesis over cell division.
Andrew D. Berti +2 more
doaj +1 more source
Clinically Approved Antibiotics from 2010 to 2022
CHIMIA, 2023 This review discusses small molecule antibiotics approved for clinical use in the time frame 2010-2022. This time span saw the approval of four synthetic antibiotics (bedaquiline, pretomanid, delafloxacin, tedizolid), nine natural product derivatives ...
Erik Jung, Karl Gademann
doaj +1 more source
Pharmacokinetics/pharmacodynamics of marbofloxacin in a Pasteurella multocida serious murine lung infection model [PDF]
, 2015 The ARRIVE Guidelines Checklist. Animal Research: Reporting In Vivo Experiments.
Changfu Cao +6 more
core +2 more sources
SMT19969 as a treatment for Clostridium difficile infection : an assessment of antimicrobial activity using conventional susceptibility testing and an in vitro gut model [PDF]
, 2015 © The Author 2014. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org ...
Best +12 more
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