Results 1 to 10 of about 1,887 (161)

In vitro persistence of clinical methicillin-resistant Staphylococcus aureus isolates from bone and joint infections after exposure to daptomycin, telavancin, and vancomycin [PDF]

Microbiology Spectrum
Bacterial persistence is linked to chronic infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Understanding the persister profiles of daptomycin, telavancin, and vancomycin is crucial because MRSA bone and joint infections (BJIs ...
Aliaa Fouad, Joseph L. Kuti, Christian M. Gill   +2 more
doaj   +2 more sources

Efficacy and safety of telavancin in clinical trials: a systematic review and meta-analysis.

PLoS ONE, 2012
IntroductionThe epidemiology and antibiotic resistance of Staphylococcus aureus have evolved, underscoring the need for novel antibiotics, particularly against methicillin-resistant S. aureus (MRSA).
Konstantinos A Polyzos, Michael N Mavros, Konstantinos Z Vardakas, Marinos C Makris, Petros I Rafailidis, Matthew E Falagas   +5 more
doaj   +2 more sources

Critical genomic insights into vancomycin-resistant Enterococcus faecium in Lebanon [PDF]

Microbiology Spectrum
Vancomycin-resistant Enterococcus faecium (VRE) poses a global public health threat, with particularly severe ramifications in low-resource settings. While E.
Marwan Osman, Iman Yassine, Jouman Hassan, Jessica E. Ericson, Steven J. Schiff, Anahita Ghorbani Tajani, Bledar Bisha, Monzer Hamze, Issmat I. Kassem   +8 more
doaj   +2 more sources

Omadacycline for the treatment of acute bacterial skin and skin structure infections: a systematic review and network meta-analysis [PDF]

BMC Infectious Diseases
Background Few studies have compared the efficacy and safety of omadacycline with other treatments for acute bacterial skin and skin structure infections (ABSSSI). Therefore, updated meta-analyses on this topic is necessary.
Wen-qiang Kong, Yun-feng Shu , Juan Tang, Shi-qin Li, Hong Zhong, Xuan-yi Zhang   +5 more
doaj   +2 more sources

Proportion and antibiogram of methicillin-resistant Staphylococcus aureus (MRSA) in Africa: a systematic review and meta-analysis [PDF]

Antimicrobial Resistance and Infection Control
Background Methicillin-resistant Staphylococcus aureus (MRSA) is a major public health concern, particularly in resource-limited settings such as Africa. This meta-analysis aimed to determine the proportion of MRSA among S.
Ahmed Azzam, Heba Khaled, Ahmed Salem, Muhamad Sayed, Abdelmarouf Mohieldein, Mohamed S. Elsayed, Enas Mohamed Lotfy, Hend H. A. M. Abdullah, Fatma E. Hassan, Hassan Marei, Nouran Hassan, Elham Abdulnaby, Gellan Alaa Mohamed Kamel, Ismael Osman, Mohamed Ahmed Reda, Dina Ismail, Mahmoud Nazih, Haitham Salem, Amar Basil, Dina Rady   +19 more
doaj   +2 more sources

Glycopeptide Antibiotics: Structural and Functional Aspects, Human Medicinal Use, and Standardisation

Регуляторные исследования и экспертиза лекарственных средств, 2023
In recent years, glycopeptide antibiotics have been widely used to treat severe bacterial infections. The long-term use of first-generation antibiotics of this group (vancomycin, teicoplanin) has contributed to the emergence of bacteria resistant to them.
O. N. Vysochanskaya, S. I. Kuleshova, E. P. Simonova   +2 more
doaj   +1 more source

Regional analysis of telavancin and comparator antimicrobial activity against multidrug-resistant Staphylococcus aureus collected in the USA 2014–2016

Journal of Global Antimicrobial Resistance, 2020
Objectives: The in vitro antimicrobial activities of telavancin and comparator antimicrobials were evaluated against recent Staphylococcus aureus (S. aureus) clinical isolates collected in the United States of America (USA). Methods: A total of 15 882 S.
Leonard R. Duncan, Caitlin J. Smith, Robert K. Flamm, Rodrigo E. Mendes   +3 more
doaj   +1 more source

Clinical Experience with Telavancin for the Treatment of Patients with Bacteremia and Endocarditis: Real-World Results from the Telavancin Observational Use Registry (TOUR™)

Drugs - Real World Outcomes, 2020
Background Bacteremia and endocarditis caused by Staphylococcus aureus (S. aureus), particularly methicillin-resistant S. aureus (MRSA), are challenging to treat and are associated with high morbidity and mortality.
Joseph Reilly, Micah A. Jacobs, Bruce Friedman, Kerry O. Cleveland, David A. Lombardi, Bibiana Castaneda-Ruiz   +5 more
doaj   +1 more source

Comparative Activity of Lipoglycopeptide Antibiotics Against Gram-Positive Bacteria

Антибиотики и Химиотерапия, 2022
Lipoglycopeptide antibiotics are semi-synthetic derivatives of glycopeptides and are characterized by a pronounced bactericidal activity against gram-positive pathogens.
V. V. Gostev, O. S. Sulian, O. S. Kalinogorskaya, L. N. Popenko, A. N. Kruglov, S. A. Gordeeva, E. V. Nesterova, D. P. Gladin, N. N. Trophimova, P. S. Chulkova, I. V. Ageevets, V. A. Ageevets, T. V. Chernenkaya   +12 more
doaj   +1 more source

Antibacterial activity of recently approved antibiotics against methicillin-resistant Staphylococcus aureus (MRSA) strains: A systematic review and meta-analysis

Annals of Clinical Microbiology and Antimicrobials, 2022
Background Methicillin-resistant Staphylococcus aureus (MRSA) infections are considered an important public health problem, and treatment options are limited.
Fei Liu, Sajad Rajabi, Chunhua Shi, Ghazale Afifirad, Nazanin Omidi, Ebrahim Kouhsari, Saeed Khoshnood, Khalil Azizian   +7 more
doaj   +1 more source