Results 151 to 160 of about 5,007,317 (352)

Cigarette Smoke Exposure Attenuates T2R‐Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Tobacco use is associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). Bitter taste receptor (T2R) activation induces apoptosis via calcium‐dependent signaling, and higher T2R expression correlates with increased survival in HNSCC.
Kyle Polen, Sarah Sywanycz, Gavin Turner, Brianna L. Hill, Lily Huang, Zoey A. Miller, Casey Hanna, Lovely Raghav, Devraj Basu, Robert J. Lee, Ryan M. Carey   +10 more
wiley   +1 more source

Impact of Smoking on Treatment Outcomes in Patients With Human Papillomavirus‐Related Oropharyngeal Cancer

Head &Neck, EarlyView.
ABSTRACT Background Patients with HPV+ oropharyngeal cancer (OPC) have worse outcomes with longer smoking history (≥ 10 pack‐years). This has been confirmed in trials of primary radiotherapy but not surgery, suggesting differential smoking impact by treatment received. We assessed smoking‐related outcomes at a single institution.
Michelle M. Kwan, Latifa A. Bazzi, Zequn Sun, Dayton Rand, Asher Park, Shravan Asthana, Alexis Larson, Poonam Yadav, Bharat B. Mittal, Adil Akthar, Sarah Kramer, Jochen H. Lorch, Sandeep Samant, Urjeet Patel, Michelle L. Mierzwa, Leila J. Mady, Katelyn O. Stepan, Laila A. Gharzai   +17 more
wiley   +1 more source

Comparison of In‐Office and General Anesthesia Biopsies for Oropharyngeal Squamous Cell Carcinoma in a Public Healthcare System

Head &Neck, EarlyView.
ABSTRACT Background We compared treatment delays, costs, and management impact between oropharyngeal squamous cell carcinoma (OPSCC) patients undergoing in‐office versus general anesthesia panendoscopy‐guided biopsies in two large tertiary centers in a public healthcare system. Methods All OPSCC patients included were treated between 2010 and 2024 with
Samuel Bellavance, Michel Khoury, Justine Colivas, Jonathan Primiani, Gabriel Dayan, Eric Bissada, Tareck Ayad, Apostolos Christopoulos, Jean‐Claude Tabet, Louis Guertin, Paul Tabet   +10 more
wiley   +1 more source

How do beliefs about different human papillomavirus-related diseases vary among young gay, bisexual, and other men who have sex with men in the United States?

Preventive Medicine Reports
Purpose: To determine how beliefs about various disease outcomes caused by human papillomavirus (HPV) infection differ among young gay, bisexual, and other men who have sex with men (YGBMSM). Methods: From 2019 to 2021, we recruited cisgender YGBMSM ages
Paul L. Reiter, Amy L. Gower, Abigail B. Shoben, Annie-Laurie McRee   +3 more
doaj   +1 more source

Pharyngeal and Cervical Cancer Incidences Significantly Correlate with Personal UV Doses Among Whites in the United States [PDF]

, 2014
Because we found UV-exposed oral tissue cells have reduced DNA repair and apoptotic cell death compared with skin tissue cells, we asked if a correlation existed between personal UV dose and the incidences of oral and pharyngeal cancer in the United ...
Godar, Dianne E., Merrill, Stephen, Tang, Rong   +2 more
core   +1 more source

Associations Between Preexisting Depression and Anxiety and Postoperative Outcomes Among Medicare Beneficiaries Undergoing Head and Neck Cancer Surgery

Head &Neck, EarlyView.
ABSTRACT Introduction Depression and anxiety are common in patients with head and neck cancer (HNC), but their impacts on postoperative outcomes after major HNC surgery are not well defined. We evaluated whether preexisting, clinically diagnosed depression or anxiety independently predicted short‐term postoperative outcomes among adults undergoing HNC ...
Xiaodan Hu, Daniel Gilmore, Ericka L. Erickson, Catherine T. Haring, Kyle VanKoevering, Nolan B. Seim, Stephen Y. Kang, James W. Rocco, Ann Scheck McAlearney, Lauren E. Miller   +9 more
wiley   +1 more source

Variations in Treatment Prescription and Survival Outcomes Between Older and Younger Patients With Mucosal Head and Neck Squamous Cell Carcinoma Treated With Radiotherapy

Head &Neck, EarlyView.
ABSTRACT Purpose To investigate treatment variations and outcomes between older (≥ 70 years) and younger (< 70 years) patients with mucosal head and neck squamous cell carcinoma (mHNSCC) treated with radiotherapy. Methods A multicenter retrospective review of patients diagnosed from 2010 to 2018 was conducted.
Farhannah Aly, Joseph Descallar, Purnima Sundaresan, Alexis Andrew Miller, Lois Holloway, Shalini Vinod   +5 more
wiley   +1 more source

THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCER

Кубанский научный медицинский вестник, 2016
This article provides review of foreign literature on the problem of HPV-associated oropharyngeal cancer incidence. Epidemiological researches demonstrate increase of incidence of oropharyngeal squamous cell carcinoma (OPSCC) especially among white men ...
A. I. Stukan, V. N. Bodnya, E. V. Dulina, A. A. Leonov, V. I. Aleksandrov   +4 more
doaj  

A theory for the tissue specificity of BRCA1/2 related and other hereditary cancers [PDF]

, 2010
Women who inherit a defective BRCA1 or BRCA2 gene have risks for breast and ovarian cancer that are so high and seem so selective that many mutation carriers choose to have prophylactic surgery. There has been much conjecture to explain such apparently
Bernard Friedenson
core   +1 more source

Awareness of Human Papillomavirus (HPV), Increasing Rates of Oropharyngeal Cancer, and Estimated Economic Burden in Denmark

International Journal of Cancer, EarlyView.
Human papillomavirus (HPV) is a highly prevalent sexually transmitted infection. This comprehensive assessment of HPV public awareness in Denmark shows that despite the high national HPV vaccination coverage and growing public health focus on HPV‐related diseases, more than one‐third of survey respondents had never heard of HPV and fewer than 40 ...
Kathrine Kronberg Jakobsen, Umar Rehman, Christian Grønhøj, Zi Jian Lau, Jens Peter Klussmann, Matt Lechner, Christian von Buchwald   +6 more
wiley   +1 more source