Results 51 to 60 of about 3,268,068 (297)

Association of Prevotella intermedia with oropharyngeal cancer: A patient-control study

Heliyon, 2023
Objective: To investigate the frequencies and bacterial load of three species of periodontal bacteria in samples from oropharyngeal cancer patients versus healthy individuals.
Gabriel-Jaime Castañeda-Corzo, Luís-Felipe Infante-Rodríguez, Jean-Carlos Villamil-Poveda, Jairo Bustillo, Angel Cid-Arregui, Dabeiba-Adriana García-Robayo   +5 more
doaj   +1 more source

Clinical utility of pharyngeal high‐resolution manometry with impedance for upper esophageal sphincter dysfunction in gastroenterology

Advances in Digestive Medicine, EarlyView.
Abstract Pharyngeal high‐resolution manometry with impedance (P‐HRM‐I) is an established assessment method used to evaluate pharyngeal swallowing. It provides precise quantification of swallowing biomechanics that enable the detection of alterations in swallowing physiology.
Mistyka Schar, Taher Omari, Michal Szczesniak, Chien‐Lin Chen, Richard Heddle, Charles Cock   +5 more
wiley   +1 more source

The Human Papilloma Virus is a New Etiologic Factor in the Development of Cancer of the Head and Neck Organs. Problems and Prospects for their Solution

Эпидемиология и вакцинопрофилактика, 2018
Squamous cell carcinoma of the head and neck organs occupies the 5th place in the structure of oncological morbidity in the world. The mortality from this pathology has not changed for several decades, despite significant successes and achievements in ...
A. M. Mudunov
doaj   +1 more source

Dynamic change of the systemic immune inflammation index is a risk factor for patients with oropharyngeal cancer: a case control study and an additional HPV-status subgroup analysis

European Journal of Medical Research, 2023
Background The study aimed to analyze the relationship between the dynamic systemic immune inflammation index (SII), human papillomavirus (HPV) infection, and the prognosis of oropharyngeal cancer patients. Method We retrospectively obtained the data for
XiaoChuan Gan, QiTao Gou, Jing Zhu, Tao Zhang   +3 more
doaj   +1 more source

Tonsillectomy and Incidence of Oropharyngeal Cancers [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2016
Abstract Background: Rising incidence of oropharyngeal cancers in numerous countries since the 1970s has been attributed to increased oral human papillomavirus (HPV) exposure. However, the contribution of coincidental declines in the surgical removal of the tonsils (tonsillectomy) is unknown.
Anil K, Chaturvedi, Huan, Song, Phillip S, Rosenberg, Torbjorn, Ramqvist, William F, Anderson, Eva, Munck-Wikland, Weimin, Ye, Tina, Dalianis   +7 more
openaire   +2 more sources

Recurrent Neurodevelopmental Disorder Associated With a Dominant‐Negative TOP2B H63Y Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a 7 year‐old boy with severe neurodevelopmental disorder, medically‐refractory epileptic encephalopathy, hyperkinetic movement disorder, hypotonia, cerebral and cerebellar atrophy and hypomyelination who was found to have a heterozygous de novo TOP2B NM_001330700.2:c.187C>T, p.(His63Tyr) variant.
Zong Yi Ha, Leticia Dinatto, Kirsten Meagher, Colleen Guimond, Jan M. Friedman, Peter C. Stirling, Millan S. Patel   +6 more
wiley   +1 more source

Oral and oropharyngeal cancer: Knowledge, attitude and practices among medical and dental practitioners

Cancer Reports, 2021
Background Oral and oropharyngeal cancer are significant health problems. They are both life‐threatening conditions usually diagnosed at an advanced stage causing survival rates to decline.
Latifa Yousef Algudaibi, Shahad AlMeaigel, Nouf AlQahtani, Naila A. Shaheen, Ali Aboalela   +4 more
doaj   +1 more source

Expert Perspectives: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Treat‐to‐target has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal treat‐to‐target framework for adult IIM has not yet been ...
Shiri Keret, Nantakarn Pongtarakulpanit, Rohit Aggarwal   +2 more
wiley   +1 more source

Safety and pharmacokinetics of inhaled aloxistatin: A first‐in‐human phase 1 dose escalation trial

British Journal of Clinical Pharmacology, EarlyView.
Aims Aloxistatin (E64d) is a membrane‐permeable cysteine protease inhibitor prodrug that is converted by esterases to the active metabolite E64c (loxistatin). This first‐in‐human study evaluated the safety, tolerability and pharmacokinetics of single ascending doses of inhaled E64d in healthy volunteers.
Sebastian Fähndrich, Franziska Friedrich, Daniel Soriano, Jona Gjeloshi, Björn C. Frye, Xuan Phuoc Nguyen, Lydia Herbstritt, Caroline von Spee‐Mayer, Britta Lang, Fabrice Nollevaux, Andreas Hoheisel, Dorothee Winterberg, Armin Braun, Thomas Epting, Christine Contini, Karl Winkler, Thomas Reinheckel, Franziska C. Trudzinski, Gernot Rohde, Daiana Stolz, Robert Bals, Martin J. Hug, Sebastian Wirtz, Christoph Peters, Carolin Jenkner   +24 more
wiley   +1 more source

Implications of the Oropharyngeal Cancer Epidemic [PDF]

Journal of Clinical Oncology, 2011
Chaturvedi et al,1 analyzing specimens back to 1984, validate the long-held hypothesis that infection with human papillomavirus (HPV) has increased oropharyngeal squamous cell carcinoma (OPSCC) incidence in the US. They find the incidence of OPSCC in men—who have higher risks of both HPV-positive and HPV-negative OPSCC than women—similar to that of ...
Edmund A, Mroz, Arlene A, Forastiere, James W, Rocco   +2 more
openaire   +2 more sources