Results 31 to 40 of about 1,311 (145)

OROV genome coverage generated from six OROV-positive patient plasma samples, using a metagenomic sequencing approach.

open access: yes, 2020
Reads were mapped to reference sequences OROV/EC/Esmeraldas/087/2016 (GenBank accessions MF926352.1- MF926354.1). Panel A: OROV genome segment (S, M, L) coverage (%). qRT-PCR Cq value is given at the top of each plot.
Emma L. Wise (4911469)   +13 more
core   +1 more source

Arrival of Oropouche Virus in a Nonendemic Area in Northeastern Brazil, 2024. [PDF]

open access: yesJ Med Virol
ABSTRACT Orthobunyavirus oropoucheense (OROV) causes Oropouche fever, which exhibits symptoms similar to those of other arboviral diseases. Although it has historically been restricted to the Amazon region, the virus has recently spread to other areas of Brazil.
Nascimento JPM   +14 more
europepmc   +2 more sources

Sloths host Anhanga virus‐related phleboviruses across large distances in time and space

open access: yesTransboundary and Emerging Diseases, Volume 67, Issue 1, Page 11-17, January 2020., 2020
Abstract Sloths are genetically and physiologically divergent mammals. Phleboviruses are major arthropod‐borne viruses (arboviruses) causing disease in humans and other animals globally. Sloths host arboviruses, but virus detections are scarce. A phlebovirus termed Anhanga virus (ANHV) was isolated from a Brazilian Linnaeus's two‐toed sloth (Choloepus ...
Edmilson F. de Oliveira Filho   +8 more
wiley   +1 more source

OROV replication cycle.

open access: yes, 2018
HeLa cells infected with OROV were analyzed during the virus cycle. (A) Virus titers were determined by TCID50 assay in Vero cells. Data are the mean ± SD of three independent experiments and are displayed as TCID50/mL.
Leila R. Mendonça (5172329)   +11 more
core   +1 more source

Informing Viral Surveillance of Oropouche Virus: an emerging arbovirus [PDF]

open access: yes, 2021
Arboviruses are viruses transmitted by hematophagous arthropod vectors. Many of these viruses pose a threat to human health. While some infections may be asymptomatic, others may produce febrile illness, or manifest in life threatening conditions ...
Walsh, Christine E
core   +1 more source

Observational Characterization of the Ecological and Environmental Features Associated with the Presence of Oropouche Virus and the Primary Vector Culicoides paraensis: Data Synthesis and Systematic Review

open access: yesTropical Medicine and Infectious Disease, 2021
Oropouche virus (OROV), a member of the Orthobunyavirus genus, is an arthropod-borne virus (arbovirus) and is the etiologic agent of human and animal disease.
Christine E. S. Walsh   +2 more
doaj   +1 more source

OROV viral factories derive from Golgi membranes.

open access: yes, 2018
(A) Mock infected and (B) OROV infected HeLa cells at 18 h p.i.. White arrowheads show dilated Golgi cisternae. (C) Boxed area in (B) showing virus inside the Golgi cisternae (black arrowheads).
Leila R. Mendonça (5172329)   +11 more
core   +1 more source

Knockdown of Tsg101 and Alix disrupt OROV assembly.

open access: yes, 2018
HeLa cells were transfected with control, Tsg101#1 or Alix#1 siRNAs and infected with OROV (MOI = 1). (A-C) After 24 h p.i, cells were stained with anti-OROV antibody and analyzed by confocal microscopy. Bars = 10 μm.
Leila R. Mendonça (5172329)   +11 more
core   +1 more source

Data_Sheet_1_Neural Infection by Oropouche Virus in Adult Human Brain Slices Induces an Inflammatory and Toxic Response.pdf

open access: yes, 2021
Oropouche virus (OROV) is an emerging arbovirus in South and Central Americas with high spreading potential. OROV infection has been associated with neurological complications and OROV genomic RNA has been detected in cerebrospinal fluid from patients ...
Flávio P. Veras (11744039)   +17 more
core   +1 more source

Immunoinformatics Approach for Epitope‐Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus

open access: yesJournal of Immunology Research, Volume 2018, Issue 1, 2018., 2018
Oropouche virus (OROV) is an emerging pathogen which causes Oropouche fever and meningitis in humans. Several outbreaks of OROV in South America, especially in Brazil, have changed its status as an emerging disease, but no vaccine or specific drug target is available yet.
Utpal Kumar Adhikari   +3 more
wiley   +1 more source

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