Results 51 to 60 of about 822 (132)
Clinical and laboratory profiles of Oropouche virus disease from the 2024 outbreak in Manaus, Brazilian Amazon.
PLoS Neglected Tropical DiseasesBackgroundThe 2024 Oropouche virus (OROV) outbreak in Brazil raised public health concerns due to its unprecedented rapid spread, high incidence, and potential neurological complications.Maria Paula Gomes Mourão, Gisely Cardoso de Melo, Joabi Nascimento, Victor Irungu Mwangi, Livia Sacchetto, Luiz Gustavo Gardinassi, Rebeca Linhares Abreu Netto, Jady Mota, Sergio Damasceno Pinto, Mayara Tavares, Liz Moreira Cordeiro, Barbara Seffair de Castro, de Abreu Brasil, Dyandra Dos Santos Porto, Bianca Daniele Silva de Oliveira, Ana Carolina Shuan Laco, Lorenna Pereira de Souza, Karolaine Oliveira Bentes, Marcia Castilho, Carlos Eduardo Morais, Heline Silva Lira, Luís Felipe Alho, Flor Ernestina Martínez Espinosa, Vanderson Sampaio, Felipe Murta, Marco Aurélio Sartim, Maurício Lacerda Nogueira, Marcus Lacerda, Wuelton Monteiro +28 moredoaj +1 more sourceGeographic Expansion of Oropouche Fever Into Non‐Endemic Regions of Brazil: Implications for Health Surveillance
Journal of Medical Virology, Volume 97, Issue 12, December 2025.ABSTRACT
Oropouche fever is an arboviral disease caused by the Oropouche virus (OROV; Peribunyaviridae family), first identified in Brazil in 1960. This study aims to describe the epidemiological profile and spatio‐temporal dispersion of Oropouche fever cases across Brazil in 2024.Rafael Pedro de Souza Nascimento, Paula Esbaltar de Oliveira, Adeilton Gonçalves da Silva Junior, Riana Oliveira Fernandes Amorim, Cleison Keulys dos Santos Silva, Daniela Silva Santos, Lethícia Lohane Almeida Barros, Hernany Fabricio de Novaes Menezes, Anderson da Costa Armstrong, Rodrigo Feliciano do Carmo, Carlos Dornels Freire de Souza +10 morewiley +1 more sourceOropouche Virus Importation in Southern Brazil and Emerging Concern Calling for Enhanced Public Health Surveillance
Journal of Medical Virology, Volume 97, Issue 8, August 2025.ABSTRACT
Oropouche virus (OROV), an arthropod‐borne virus transmitted by Culicoides paraensis, is an endemic arbovirus that historically circulates mostly in the Amazon basin. Between 2022 and 2024, it reemerged as a more widespread public health concern in South America.Franciellen Machado dos Santos, Elverson Soares de Melo, Gustavo Barbosa de Lima, Alexandre Freitas da Silva, Marcelo Henrique Santos Paiva, Bartolomeu Acioli‐Santos, Clarice Neuenschwander Lins de Moraes, Amanda Pellenz Ruivo, Tatiana Schäffer Gregianini, Milena Bauermann, Thales Bermann, Valeska Lizzi Lagranha, Ludmila Fiorenzano Baethgen, Fernanda Godinho, Gabriel da Luz Wallau, Ana Beatriz Gorini da Veiga, Richard Steiner Salvato +16 morewiley +1 more sourceEmergence of Oropouche Virus in Espírito Santo State, Brazil, 2024
Emerging Infectious Diseases
Oropouche virus (OROV), historically endemic to the Amazon, had spread to nearly all Brazil states by 2024; Espírito Santo emerged as a transmission hotspot in the Atlantic Forest biome.Edson Delatorre, Gabriela Colombo de Mendonça, Felipe Donateli Gatti, Anna Clara Gregório Có, Julia del Piero Pereira, Eric Arrivabene Tavares, Joana Zorzal Nodari, Agata Rossi, Suwellen Sardinha Dias de Azevedo, Cláudio Tavares Sacchi, Karoline Rodrigues Campos, Adriana Bugno, Lyvia Neves Rebello Alves, Lucas André Silva Bonela, Jaqueline Pegoretti Goulart, Thiago de Jesus Sousa, Felipe Gomes Naveca, Rodrigo Ribeiro-Rodrigues +17 moredoaj +1 more sourceScreening and Identification of Multiple Peptides Homologous to the Fusion Glycoprotein Gc of Schmallenberg Virus Able to Inhibit Viral Infection
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.Arthropod‐borne viruses have been responsible for several emerging infections, causing a global issue in both human and veterinary fields. Within the Orthobunyaviruses, a novel and major member is the Schmallenberg virus (SBV) first detected in central Europe in 2011, and soon after was able to spread all over the continent by causing severe infection ...Carla Zannella, Rinaldo Grazioso, Annalisa Chianese, Valentina Iovane, Biagio Santella, Serena Montagnaro, Giuseppe Greco, Ugo Pagnini, Gianluigi Franci, Anna De Filippis, Giuseppe Iovane, Carla Isernia, Massimiliano Galdiero, Shao-Lun Zhai +13 morewiley +1 more sourceOropouche Virus Infects, Persists and Induces IFN Response in Human Peripheral Blood Mononuclear Cells as Identified by RNA PrimeFlow™ and qRT-PCR Assays
Viruses, 2020 Oropouche orthobunyavirus (OROV) is an emerging arbovirus with a high potential of dissemination in America. Little is known about the role of peripheral blood mononuclear cells (PBMC) response during OROV infection in humans.Mariene Ribeiro Amorim, Marjorie Cornejo Pontelli, Gabriela Fabiano de Souza, Stéfanie Primon Muraro, Daniel A. Toledo-Teixeira, Julia Forato, Karina Bispo-dos-Santos, Natália S. Barbosa, Matheus Cavalheiro Martini, Pierina Lorencini Parise, Aline Vieira, Guilherme Paier Milanez, Luis Lamberti Pinto daSilva, Pritesh Jaychand Lalwani, Alessandro Santos Farias, Marco Aurélio Ramirez Vinolo, Renata Sesti-Costa, Eurico Arruda, Jose Luiz Proenca-Modena +18 moredoaj +1 more sourceGenomic and phenotypic characterization of the Oropouche virus strain implicated in the 2022–24 large‐scale outbreak in Brazil
Journal of Medical Virology, Volume 96, Issue 10, October 2024.Abstract
The Orthobunyavirus oropoucheense species encompasses a group of arthropod‐borne zoonotic viruses transmitted by biting midges to animals including humans. Several large‐scale human outbreaks caused by the prototype member of this species, Oropouche virus (OROV) have been documented since the 1970s and were primarily confined to the Amazon ...Elisa de A. N. Azevedo, Alexandre F. da Silva, Verônica G. da Silva, Lais C. Machado, Gustavo B. de Lima, Bruno I. M. Ishigami, Keilla M. Paz e Silva, Mayara M. de O. M. da Costa, Diego A. Falcão, Andreza P. Vasconcelos, Clintiano C. da Silva, Felipe G. Naveca, Matheus F. Bezerra, Tulio de L. Campos, Bartolomeu Acioli‐Santos, Marcelo H. S. Paiva, Clarice N. L. de Morais, Gabriel L. Wallau +17 morewiley +1 more sourceRab27a GTPase and its effector Myosin Va are host factors required for efficient Oropouche virus cell egress.
PLoS PathogensOropouche fever, a debilitating illness common in South America, is caused by Oropouche virus (OROV), an arbovirus. OROV belongs to the Peribunyaviridae family, a large group of RNA viruses.Juan O Concha, Kristel Gutierrez, Natalia Barbosa, Roger L Rodrigues, Andreia N de Carvalho, Lucas A Tavares, Jared S Rudd, Cristina S Costa, Barbara Y G Andrade, Enilza M Espreafico, Colin M Crump, Luis L P daSilva +11 moredoaj +1 more sourceDevelopment of monoclonal antibodies against oropouche virus and its applicability to immunohistochemical diagnosis
Virology JournalOrthobunyavirus oropouche ense virus (OROV), the causative agent of Oropouche fever, is widely dispersed in Brazil and South America, causing sporadic outbreaks.Ana Paula Andreolla, Alessandra Abel Borges, Seigo Nagashima, Caroline Busatta Vaz de Paula, Lucia de Noronha, Nilson I.T. Zanchin, Juliano Bordignon, Claudia Nunes Duarte dos Santos +7 moredoaj +1 more sourceInsights into the expansion of Oropouche virus in Brazil: epidemiological and environmental aspects
Experimental Biology and MedicineThe Oropouche virus (OROV), an arbovirus transmitted primarily by the Culicoides paraensis midge, has caused significant outbreaks in the Americas, especially in the Amazon region.Igor Pereira Godinho, Ítalo Faria Dória, Victor de Melo Rocha, Bárbara Alves Miranda, Lucas Fernandes Chamhum Salomão, Brunello Stancioli, Adriana Alves Oliveira Paim, Jordana G. Alves Coelho dos Reis, Samille Henriques Pereira, Flávio Guimarães da Fonseca +9 moredoaj +1 more source
