Results 51 to 60 of about 1,311 (145)

Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1 [PDF]

, 2022
Oropouche orthobunyavirus (OROV; Peribunyaviridae) is a mosquito-transmitted virus that causes widespread human febrile illness in South America, with occasional progression to neurologic effects.
Sarah H. Stubbs, Annie Feng, Ganaie, Safder S, Mishra, Nawneet, Whelan, Sean P J, Nawneet Mishra, Hartman, Amy L, Price, David A, Egawa, Takeshi, Whelan, Sean P. J., Schwarz, Madeline M, Daisy W. Leung, Hartman, Amy L., Hoehl, Ryan M, David A. Price, Ryan M. Hoehl, Amy L. Hartman, Leung, Daisy W, Hoehl, Ryan M., Amarasinghe, Gaya K, Xiaoxia Cui, Feng, Annie, Takeshi Egawa, Fatma, Farheen, Schwarz, Madeline M., Ganaie, Safder S., Gaya K. Amarasinghe, Cui, Xiaoxia, Safder S. Ganaie, Farheen Fatma, Stubbs, Sarah H, Stubbs, Sarah H., Price, David A., Amarasinghe, Gaya K., Sean P. J. Whelan, Leung, Daisy W., Madeline M. Schwarz   +36 more
core   +1 more source

Oropouche Virus Importation in Southern Brazil and Emerging Concern Calling for Enhanced Public Health Surveillance

Journal of Medical Virology, Volume 97, Issue 8, August 2025.
ABSTRACT Oropouche virus (OROV), an arthropod‐borne virus transmitted by Culicoides paraensis, is an endemic arbovirus that historically circulates mostly in the Amazon basin. Between 2022 and 2024, it reemerged as a more widespread public health concern in South America.
Franciellen Machado dos Santos, Elverson Soares de Melo, Gustavo Barbosa de Lima, Alexandre Freitas da Silva, Marcelo Henrique Santos Paiva, Bartolomeu Acioli‐Santos, Clarice Neuenschwander Lins de Moraes, Amanda Pellenz Ruivo, Tatiana Schäffer Gregianini, Milena Bauermann, Thales Bermann, Valeska Lizzi Lagranha, Ludmila Fiorenzano Baethgen, Fernanda Godinho, Gabriel da Luz Wallau, Ana Beatriz Gorini da Veiga, Richard Steiner Salvato   +16 more
wiley   +1 more source

Inhibition of miR-217 and miR-576-3p affects OROV replication.

, 2018
HuH-7 cells were transfected with 75 nM negative control inhibitor, miR-217 inhibitor, miR-576-3p inhibitor or both. 3 h post transfection, cells were infected with OROV at MOI 1 and RT-qPCR was performed to measure miRNA, target genes and OROV RNA ...
Eurico Arruda (146843), Renato Santana Aguiar (4580458), Anibal Silva de Oliveira (5309948), Victor Emmanuel Viana Geddes (5309945), Amilcar Tanuri (7885), Marcelo Ribeiro-Alves (184765)   +5 more
core   +1 more source

Screening and Identification of Multiple Peptides Homologous to the Fusion Glycoprotein Gc of Schmallenberg Virus Able to Inhibit Viral Infection

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Arthropod‐borne viruses have been responsible for several emerging infections, causing a global issue in both human and veterinary fields. Within the Orthobunyaviruses, a novel and major member is the Schmallenberg virus (SBV) first detected in central Europe in 2011, and soon after was able to spread all over the continent by causing severe infection ...
Carla Zannella, Rinaldo Grazioso, Annalisa Chianese, Valentina Iovane, Biagio Santella, Serena Montagnaro, Giuseppe Greco, Ugo Pagnini, Gianluigi Franci, Anna De Filippis, Giuseppe Iovane, Carla Isernia, Massimiliano Galdiero, Shao-Lun Zhai   +13 more
wiley   +1 more source

Genomic and phenotypic characterization of the Oropouche virus strain implicated in the 2022–24 large‐scale outbreak in Brazil

Journal of Medical Virology, Volume 96, Issue 10, October 2024.
Abstract The Orthobunyavirus oropoucheense species encompasses a group of arthropod‐borne zoonotic viruses transmitted by biting midges to animals including humans. Several large‐scale human outbreaks caused by the prototype member of this species, Oropouche virus (OROV) have been documented since the 1970s and were primarily confined to the Amazon ...
Elisa de A. N. Azevedo, Alexandre F. da Silva, Verônica G. da Silva, Lais C. Machado, Gustavo B. de Lima, Bruno I. M. Ishigami, Keilla M. Paz e Silva, Mayara M. de O. M. da Costa, Diego A. Falcão, Andreza P. Vasconcelos, Clintiano C. da Silva, Felipe G. Naveca, Matheus F. Bezerra, Tulio de L. Campos, Bartolomeu Acioli‐Santos, Marcelo H. S. Paiva, Clarice N. L. de Morais, Gabriel L. Wallau   +17 more
wiley   +1 more source

Rab27a GTPase and its effector Myosin Va are host factors required for efficient Oropouche virus cell egress.

PLoS Pathogens
Oropouche fever, a debilitating illness common in South America, is caused by Oropouche virus (OROV), an arbovirus. OROV belongs to the Peribunyaviridae family, a large group of RNA viruses.
Juan O Concha, Kristel Gutierrez, Natalia Barbosa, Roger L Rodrigues, Andreia N de Carvalho, Lucas A Tavares, Jared S Rudd, Cristina S Costa, Barbara Y G Andrade, Enilza M Espreafico, Colin M Crump, Luis L P daSilva   +11 more
doaj   +1 more source

Heat map of differentially expressed miRNAs in OROV infected HuH-7 cells.

, 2018
Depiction of the 13 miRNAs differentially expressed in OROV infected cells relative to uninfected cells. Lines represent individual miRNAs and columns represent independent replicates (four mock infected and five OROV infected).
Eurico Arruda (146843), Renato Santana Aguiar (4580458), Anibal Silva de Oliveira (5309948), Victor Emmanuel Viana Geddes (5309945), Amilcar Tanuri (7885), Marcelo Ribeiro-Alves (184765)   +5 more
core   +1 more source

Insights into the expansion of Oropouche virus in Brazil: epidemiological and environmental aspects

Experimental Biology and Medicine
The Oropouche virus (OROV), an arbovirus transmitted primarily by the Culicoides paraensis midge, has caused significant outbreaks in the Americas, especially in the Amazon region.
Igor Pereira Godinho, Ítalo Faria Dória, Victor de Melo Rocha, Bárbara Alves Miranda, Lucas Fernandes Chamhum Salomão, Brunello Stancioli, Adriana Alves Oliveira Paim, Jordana G. Alves Coelho dos Reis, Samille Henriques Pereira, Flávio Guimarães da Fonseca   +9 more
doaj   +1 more source

Characterisation of non-coding regions of the OROV genome segments and their relevance for viral transcription/replication as well as interaction with the type-I interferon system

, 2013
The Oropouche virus (OROV) is a RNA virus from the Bunyaviridae family. Its genome consists of a single-stranded negative sense RNA. The Oropouche fever is caused by this virus and is most common in Central and South America.
Schnülle, Katharina
core   +1 more source

Viruses identified from 23 patient plasma samples by metagenomic sequencing, 17 of which were negative for all pathogens tested for by RT-PCR, including one sample (D-087) in which OROV was initially detecting by metagenomic sequencing.

, 2020
The remaining five samples (D-057, D-155, D-171, D-206 and D-210) were initially shown to be positive for OROV using the qRT-PCR assay described in this study. The cut-off value used was ≥40% genome coverage (from mapping reads to reference genome).
Emma L. Wise (4911469), Gyorgy Fejer (1367919), Verónica Paz (8339202), Simon K. Jackson (1367913), Sonia Zapata (8339205), Sully Márquez (8339199), Oliver G. Pybus (8098271), Bernardo Gutierrez (6453725), Barry Atkinson (2697406), Gabriel Trueba (328365), Christopher H. Logue (8339208), Jack Mellors (6940157), Steven T. Pullan (8339211), Josefina Coloma (27354)   +13 more
core   +1 more source