Results 31 to 40 of about 861 (60)

Cluster of human Puumala orthohantavirus infections due to indoor exposure?—An interdisciplinary outbreak investigation [PDF]

, 2022
Puumala orthohantavirus (PUUV) is the most important hantavirus species in Europe, causing the majority of human hantavirus disease cases. In central and western Europe, the occurrence of human infections is mainly driven by bank vole population dynamics
Binder, Florian, Dreesman, Johannes, Drewes, Stephan, Esser, Jutta, Freise, Jona, Hofmann, Jörg, Jacob, Jens, Meyer-Schlinkmann, Kristin M., Princk, Christina, Runge, Martin, Saathoff, Marion, Tenner, Beate, Ulrich, Rainer G., Weiss, Sabrina   +13 more
core   +2 more sources

Evaluation of a Luminex‐Based Multiplex Immunoassay of Hemorrhagic Fever Viruses in Senegal

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Given the growing threat posed by viral hemorrhagic fevers, the development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well as effective and sustainable surveillance to ensure downstream communication and preparedness. A serological approach that offers high precision and
Safietou Sankhe, Maryam Diarra, Mamadou Aliou Barry, Martin Faye, Cheikh Talla, Diogop Camara, Maimouna Mbanne, Pape Mbacke Sembene, Amadou Alpha Sall, Gamou Fall, Oumar Faye, Cheikh Loucoubar, Ousmane Faye, Ines Vigan-Womas, Keersten Michelle Ricks, Jessica Radzio-Basu, Moussa Moise Diagne, Leyi Wang   +17 more
wiley   +1 more source

Species-specific responses during Seoul orthohantavirus infection in human and rat lung microvascular endothelial cells [PDF]

Seoul orthohantavirus (SEOV) is a rat-borne zoonotic virus that is transmitted via inhalation of aerosolized infectious excreta, and can cause hemorrhagic fever with renal syndrome (HFRS) in humans worldwide.
Embregts, Carmen W.E., Koopmans, Marion P.G., Noack, Danny, Rockx, Barry, van den Hout, Mirjam C.G.N., van IJcken, Wilfred F.J.   +5 more
core   +3 more sources

Predicting Landscape Conversion Impact on Small Mammal Occurrence and the Transmission of Parasites in the Atlantic Forest

Global Ecology and Biogeography, Volume 33, Issue 12, December 2024.
ABSTRACT Aim Changes in landscape configuration significantly impact ecosystems and the services they provide, including disease regulation for both humans and wildlife. Land use conversion usually favors disturbed‐adapted species, which are often known reservoirs of zoonotic parasites, thereby potentially escalating spillover events (i.e., the ...
Ana Paula L. Costa, Gisele R. Winck, Bernardo R. Teixeira, Rosana Gentile, Paulo S. D'Andrea, Emerson M. Vieira, Renata Pardini, Thomas Püttker, Cecilia S. Andreazzi   +8 more
wiley   +1 more source

The pathogenesis of zoonotic viral infections:Lessons learned by studying reservoir hosts [PDF]

, 2023
Zoonotic viral infections that cause severe disease or even death in some people may be asymptomatic or mild in reservoir hosts. Comparison of the pathogenesis of these two host categories may potentially explain the difference in disease.
Begeman, Lineke, Koopmans, Marion P.G., Kuiken, Thijs, van Riel, Debby   +3 more
core   +1 more source

Investigation of Viral, Bacterial and Parasitic Zoonotic Diseases in Rodents in Turkey

Veterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Rodents are reservoir hosts for zoonotic pathogens. In this study, the presence of viral lymphocytic choriomeningitis and hantavirus infections, bacterial tularaemia and leptospirosis, and parasitic leishmaniasis and toxoplasmosis were investigated in 498 rodents collected in Erzurum province, Turkey.
Mehmet Ozkan Timurkan, Esin Guven, Seyda Cengiz, Hakan Aydın, Ridvan Kirman, Hamza Avcioglu   +5 more
wiley   +1 more source

Phylogeography of Puumala orthohantavirus in Europe [PDF]

, 2019
Puumala virus is an RNA virus hosted by the bank vole (Myodes glareolus) and is today present in most European countries. Whilst it is generally accepted that hantaviruses have been tightly co-evolving with their hosts, Puumala virus (PUUV) evolutionary ...
Castel, Guillaume, Chevenet, François, Cosson, Jean-François, Marianneau, Philippe, Murri, Séverine, Plyusnin, Alexander, Razzauti, Maria, Tordo, Noël   +7 more
core   +5 more sources

Orthohantavirus Isolated in Reservoir Host Cells Displays Minimal Genetic Changes and Retains Wild-Type Infection Properties [PDF]

, 2020
Orthohantaviruses are globally emerging zoonotic pathogens. While the reservoir host role of several rodent species is well-established, detailed research on the mechanisms of host-othohantavirus interactions has been constrained by the lack of an ...
Aaltonen, Kirsi, Ahola, Paula, Eckerle, Isabella, Forbes, Kristian M., Hepojoki, Jussi, Kipar, Anja, Sironen, Tarja, Smura, Teemu, Strandin, Tomas, Ulrich, Rainer G., Vapalahti, Olli   +10 more
core   +3 more sources

Patients With COVID-19 Have Elevated Levels of Circulating Extracellular Vesicle Tissue Factor Activity That Is Associated With Severity and Mortality [PDF]

, 2021
OBJECTIVE: Patients with coronavirus disease 2019 (COVID-19) have a high rate of thrombosis. We hypothesized that severe acute respiratory syndrome coronavirus 2 leads to induction of TF (tissue factor) expression and increased levels of circulating TF ...
Aguilera, Katherina, Grover, Steven P, Havervall, Sebastian, Hisada, Yohei, Lisman, Ton, Mackman, Nigel, Rosell, Axel, Thålin, Charlotte, von Meijenfeldt, Fien   +8 more
core   +1 more source

In silico design and evaluation of a multiepitope vaccine targeting the nucleoprotein of Puumala orthohantavirus

Proteins: Structure, Function, and Bioinformatics, Volume 92, Issue 10, Page 1161-1176, October 2024.
Abstract The Puumala orthohantavirus is present in the body of the bank vole (Myodes glareolus). Humans infected with this virus may develop hemorrhagic fever accompanying renal syndrome. In addition, the infection may further lead to the failure of an immune system completely.
Kunal Bhattacharya, Nongmaithem Randhoni Chanu, Saurav Kumar Jha, Pukar Khanal, Keshav Raj Paudel   +4 more
wiley   +1 more source