Results 31 to 40 of about 3,847 (223)

An Improved Workflow for the Quantification of Orthohantavirus Infection Using Automated Imaging and Flow Cytometry [PDF]

Viruses
Determination of the infectious titer is a central requirement when working with pathogenic viruses. The plaque or focus assay is a commonly used but labor- and time-consuming approach for determining the infectious titer of orthohantavirus samples.
Laura Menke, Christian Sieben
doaj   +2 more sources

Heterogeneous Puumala orthohantavirus situation in endemic regions in Germany in summer 2019 [PDF]

, 2019
Puumala orthohantavirus (PUUV) causes most human hantavirus disease cases in Europe. PUUV disease outbreaks are usually synchronized Germany-wide driven by beech mast-induced irruptions of its host (bank vole, Myodes glareolus). Recent data indicate high
Below, Diana Alexandra, Bendl, Elias, Binder, Florian, Brockmann, Stefan, Conraths, Franz Josef, Drewes, Stephan, Freise, Jona, Imholt, Christian, Jacob, Jens, Mylius, Maren, Oehme, Rainer, Saathoff, Marion, Tenhaken, Peter, Ulrich, Rainer   +13 more
core   +3 more sources

Molecular Detection of Orthohantavirus puumalaense in Plasma and Urine Samples from Hospitalized Patients Presenting with a Serologically Confirmed Acute Hantavirus Infection in France

Journal of Clinical Microbiology, 2023
Molecular detection of Orthohantavirus puumalaense (PUUV) RNA during the course of the disease has been studied in blood of patients in Sweden and Slovenia. The use of urine has been poorly investigated.
J. Reynes, L. Schaeffer, Pavlos Papadopoulos, Mohand Ait-Ahmed, Dieyenaba Siby-Diakite, Maryline Ripaux-Lefèvre, Tan-Phuc Buivan, Sylvie Lechat, M. Vray, J. Galempoix   +9 more
semanticscholar   +2 more sources

Isolation and characterization of genetic variants of Orthohantavirus hantanense from clinical cases of HFRS in Jiangxi Province, China. [PDF]

PLoS Negl Trop Dis
Background Hemorrhagic fever with renal syndrome (HFRS) is a severe public health problem in Jiangxi province, China. Previous studies reported genetic variants of Orthohantavirus hantanense (Hantaan virus, HTNV) in rodents in this area.
Liu S, Deng Z, Li J, Zou L, Sun X, Liu X, Shi Y, Huang S, Wu Y, Lei J, Liu P, Zhang P, Xiong Y, Long ZE.   +13 more
europepmc   +2 more sources

The discovery of novel variants reveals the genetic diversity and potential origin of Seoul orthohantavirus. [PDF]

PLoS Negl Trop Dis
Seoul orthohantavirus (SEOV) has been identified as one of the main causative agents of hemorrhagic fever with renal syndrome (HFRS) in China. The virus was found circulating in rodent populations in almost all provinces of the country, reflecting the ...
Kuang G, Wang J, Feng Y, Wu W, Han X, Xin G, Yang W, Pan H, Yang L, Wang J, Shi M, Gao Z.   +11 more
europepmc   +2 more sources

Orthohantavirus diversity in Central-East Argentina: Insights from complete genomic sequencing on phylogenetics, Geographic patterns and transmission scenarios. [PDF]

PLoS Negl Trop Dis
Hantavirus Pulmonary Syndrome (HPS), characterized by its high fatality rate, poses a significant public health concern in the Americas. Phylogenetic relationships of orthohantaviruses in the country were inferred from partial genomic sequences.
Alonso DO, Kehl SD, Coelho RM, Periolo N, Poklépovich Caride T, Sanchez Loria J, Cuba FG, Pérez-Sautu U, Sanchez-Lockhart M, Palacios G, Bellomo CM, Martinez VP.   +11 more
europepmc   +3 more sources

Batı Anadolu’daki Bazı Yaygın Küçük Memeli Türlerinin Orthohantavirus Taşıyıcılığı Açısından Değerlendirilmesi

ANKEM Dergisi
Hantaviridae ailesinin üyesi olan orthohantavirüsler, kemirici kaynaklı RNA virüsleridir. Enfekte kemiricilerin çıkartı ve sekresyonlarındaki viral partiküllerin aerosolizasyonu ve nadiren de enfekte kemirici iler direkt temas yolu ile bulaşan ...
Ceylan Polat, Sercan Irmak, Mustafa Sözen, Mehmet Ali Öktem   +3 more
semanticscholar   +2 more sources

Role of monocytes in endothelial glycocalyx shedding during Puumala orthohantavirus infection

medRxiv
Vascular leakage characterizes Puumala orthohantavirus (PUUV)-caused hemorrhagic fever with renal syndrome (HFRS). Disruption in the endothelial glycocalyx layer, which protects blood vessels from increased vascular leakage into tissues, may contribute ...
Luz E. Cabrera, Isaac Polanco, J. Tietäväinen, S. Mäkelä, Olli Vapalahti, Antti Vaheri, J. Mustonen, T. Strandin   +7 more
semanticscholar   +2 more sources

5,6-Dichloro-2-Phenyl-Benzotriazoles: New Potent Inhibitors of Orthohantavirus [PDF]

Viruses, 2020
Orthohantaviruses, previously known as hantaviruses (family Hantaviridae, order Bunyavirales), are emerging zoonoses hosted by different rodent and insectivore species. Orthohantaviruses are transmitted by aerosolized excreta (urine, saliva and feces) of
Giuseppina Sanna, Sandra Piras, Silvia Madeddu, Bernardetta Busonera, Boris Klempa, Paola Corona, Roberta Ibba, Gabriele Murineddu, Antonio Carta, Roberta Loddo   +9 more
doaj   +5 more sources

Tropism of Puumala orthohantavirus and Endoparasite Coinfection in the Bank Vole Reservoir

Viruses, 2023
In Europe, most cases of human hantavirus disease are caused by Puumala orthohantavirus (PUUV) transmitted by bank voles (Clethrionomys glareolus, syn. Myodes glareolus), in which PUUV causes inconspicuous infection.
E. Schlohsarczyk, S. Drewes, P. Koteja, S. Röhrs, R. Ulrich, J. Teifke, C. Herden   +6 more
semanticscholar   +6 more sources