Results 41 to 50 of about 3,847 (223)

THE DYNAMICS OF ORTHOHANTAVIRUS HANTAAN STRAINS REPLICATION ON THE MODEL OF MOUSE PERITONEAL MACROPHAGES

Acta Biomedica Scientifica, 2018
Orthohantaviruses (Orthohantavirus genus, Hantaviridae family) are the causative agents of a widespread natural focal infection in the  Russian Federation, hemorrhagic fever with renal syndrome (HFRS).
A. B. Pott, O. V. Iunikhina, I. N. Lyapun, G. G. Kompanets   +3 more
doaj   +3 more sources

Genotypic differentiation and evolutionary dynamics of puumala orthohantavirus (PUUV)

Acta Virologica
Puumala orthohantavirus (PUUV) is a causative agent of haemorrhagic fever with renal syndrome, mainly transmitted through rodent excretions. Classification of PUUV has traditionally been based on the geographic locations of their discovery, but this ...
Mariia A. Dashian, I.A. Volkhin, P. Y. Volchkov, A. Deviatkin   +3 more
semanticscholar   +3 more sources

Comparison of VSV Pseudovirus and Focus Reduction Neutralization Assays for Measurement of Anti-Andes orthohantavirus Neutralizing Antibodies in Patient Samples [PDF]

Frontiers in Cellular and Infection Microbiology, 2020
Andes orthohantavirus (ANDV) is the etiologic agent of hantavirus cardiopulmonary syndrome (HCPS), which has a case fatality rate around 35%, with no effective treatment or vaccine available.
Cecilia Vial, Annalis Whitaker, Annalis Whitaker, Jan Wilhelm, Jan Wilhelm, Jimena Ovalle, Ruth Perez, Francisca Valdivieso, Marcela Ferres, Constanza Martinez-Valdebenito, Philip Eisenhauer, Gregory J. Mertz, Jay W. Hooper, Jason W. Botten, Jason W. Botten, Pablo A. Vial, Pablo A. Vial   +16 more
doaj   +2 more sources

Glomerular Injury Is Associated with Severe Courses of Orthohantavirus Infection

Pathogens
Hemorrhagic fever with renal syndrome (HFRS) induced by Eurasian pathogenic orthohantaviruses is characterized by acute kidney injury (AKI) with often massive proteinuria.
C. Nusshag, Josephine Uhrig, Gefion Gruber, Pamela Schreiber, M. Zeier, E. Krautkrämer   +5 more
semanticscholar   +4 more sources

Quantification and kinetics of viral RNA transcripts produced in Orthohantavirus infected cells [PDF]

Virology Journal, 2018
Background Rodent borne viruses of the Orthohantavirus genus cause hemorrhagic fever with renal syndrome among people in Eurasia, and hantavirus cardiopulmonary syndrome in the Americas.
Julia Wigren Byström, Jonas Näslund, Fredrik Trulsson, Magnus Evander, Olivia Wesula Lwande, Clas Ahlm, Göran Bucht   +6 more
doaj   +5 more sources

Replication kinetics of pathogenic Eurasian orthohantaviruses in human mesangial cells [PDF]

Virology Journal
Background Eurasian pathogenic orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS) characterized by acute kidney injury (AKI). The virulence of orthohantaviruses varies enormously and direct infection of different renal cell types ...
Lukas Boegelein, Pamela Schreiber, Alexandra Philipp, Christian Nusshag, Sandra Essbauer, Martin Zeier, Ellen Krautkrämer   +6 more
doaj   +2 more sources

Spatial and Temporal Evolutionary Patterns in Puumala Orthohantavirus (PUUV) S Segment [PDF]

Pathogens, 2020
The S segment of bank vole (Clethrionomys glareolus)-associated Puumala orthohantavirus (PUUV) contains two overlapping open reading frames coding for the nucleocapsid (N) and a non-structural (NSs) protein. To identify the influence of bank vole population dynamics on PUUV S segment sequence evolution and test for spillover infections in sympatric ...
Florian Binder, René Ryll, Stephan Drewes, Sandra Jagdmann, Daniela Reil, Melanie Hiltbrunner, Ulrike Rosenfeld, Christian Imholt, Jens Jacob, Gerald Heckel, Rainer G. Ulrich   +10 more
openalex   +5 more sources

Detection of two zoonotic pathogens, <i>Seoul orthohantavirus</i> and pathogenic <i>Leptospira</i>, in rats of Bamako, Mali (2021-2023). [PDF]

One Health
Garona J, Berard A, Tatard C, Kwasiborski A, Gauthier P, Ag Atteynine S, Hourdel V, Eusebe A, Diagne C, Caro V, Brouat C, Charbonnel N, Sauvage V, Granjon L, Castel G.   +14 more
europepmc   +2 more sources

Cytokine Profiles and Antibody Response Associated to Choclo Orthohantavirus Infection [PDF]

Frontiers in Immunology, 2021
BackgroundNew World Hantaviruses (NWHs) are the etiological agent underlying hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory disease with high mortality rates in humans. In Panama, infections with Choclo Orthohantavirus (CHOV) cause a much milder illness characterized by higher seroprevalence and lower mortality rates.
Tybbysay P. Salinas, José Luis Velasco Garrido, Jacqueline R. Salazar, Publio González, Nicole Zambrano, Francisco Fuentes‐Villalobos, Felipe Bravo, Victor Fica-Leon, Alexis Salas-Burgos, Mario Calvo, Raymond A Alvarez, Blas Armién, María Inés Barría   +12 more
openalex   +5 more sources

Molecular evolution and reassortment dynamics of Orthohantavirus hantanense revealed through longitudinal genomic surveillance in the Republic of Korea. [PDF]

Sci Rep
Park K, Kim J, Kim SG, Kim WK, Song JW.
europepmc   +2 more sources