ANP32 proteins from ticks and vertebrates are key host factors for replication of Bourbon virus across species [PDF]
Journal of VirologyBourbon virus (BRBV) is a tick-borne virus in the genus Thogotovirus in the Orthomyxoviridae family. BRBV was initially identified as the presumptive causative agent of a fatal human infection in 2014 and has since been identified in ticks in the Midwest,
Zhenyu Zhang +4 more
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Reassortant Influenza A(H1N1)pdm09 Virus in Elderly Woman, Denmark, January 2021
Emerging Infectious Diseases, 2021 A case of human infection with influenza A(H1N1)pdm09 virus containing a nonstructural gene highly similar to Eurasian avian-like H1Nx swine influenza virus was detected in Denmark in January 2021. We describe the clinical case and report testing results
Jakob N. Nissen +10 more
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Severe Human Case of Zoonotic Infection with Swine-Origin Influenza A Virus, Denmark, 2021
Emerging Infectious Diseases, 2022 During routine surveillance at the National Influenza Center, Denmark, we detected a zoonotic swine influenza A virus in a patient who became severely ill. We describe the clinical picture and the genetic characterization of this variant virus, which is
Klara M. Andersen +10 more
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Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. [PDF]
PLoS Pathogens, 2010 The early host response to pathogens is mediated by several distinct pattern recognition receptors. Cytoplasmic RNA helicases including RIG-I and MDA5 have been shown to respond to viral RNA by inducing interferon (IFN) production.
Leonid Gitlin +6 more
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Биопрепараты: Профилактика, диагностика, лечение, 2021 The main triggers of new infectious diseases, including those with pandemic potential, are: spontaneous emergence of infectious strains which are more virulent for humans and contribute to transmission of pathogenic microorganisms, environmental changes,
G. G. Onishchenko +3 more
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Protective mechanism of quercetin and its derivatives in viral-induced respiratory illnesses
The Egyptian Journal of Bronchology, 2022 Globally, acute respiratory illnesses are the most commonly manifesting illness in all age group. The disease mostly affects the upper respiratory tract (URT) and is self-limiting.
Wahyu Choirur Rizky +2 more
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Molecules, 2021 As a member of the Orthomyxoviridae family of viruses, influenza viruses (IVs) are known causative agents of respiratory infection in vertebrates. They remain a major global threat responsible for the most virulent diseases and global pandemics in humans.
Sphamadla E. Mtambo +7 more
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Zoonotic Animal Influenza Virus and Potential Mixing Vessel Hosts
Viruses, 2023 Influenza viruses belong to the family Orthomyxoviridae with a negative-sense, single-stranded segmented RNA genome. They infect a wide range of animals, including humans.
Elsayed M. Abdelwhab +1 more
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Characterization of the viral microbiome in patients with severe lower respiratory tract infections, using metagenomic sequencing. [PDF]
PLoS ONE, 2012 The human respiratory tract is heavily exposed to microorganisms. Viral respiratory tract pathogens, like RSV, influenza and rhinoviruses cause major morbidity and mortality from respiratory tract disease.
Fredrik Lysholm +9 more
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Recombination Resulting in Virulence Shift in Avian Influenza Outbreak, Chile
Emerging Infectious Diseases, 2004 Influenza A viruses occur worldwide in wild birds and are occasionally associated with outbreaks in commercial chickens and turkeys. However, avian influenza viruses have not been isolated from wild birds or poultry in South America. A recent outbreak in
David L. Suarez +13 more
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