Results 41 to 50 of about 18,248 (167)
A host of factors regulating influenza virus replication. [PDF]
, 2010 A new series of genetic screens begins to illuminate the interaction between influenza virus and the infected ...
DOUDNA, Jennifer A, Mehle, Andrew
core +3 more sources
Advanced Science, EarlyView.Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang +13 more
wiley +1 more source
The interplay of co-infections in shaping COVID-19 severity: Expanding the scope beyond SARS-CoV-2
Journal of Infection and Public HealthHigh mortality has been reported in severe cases of COVID-19. Emerging reports suggested that the severity is not only due to SARS-CoV-2 infection, but also due to coinfections by other pathogens exhibiting symptoms like COVID-19.
Budhadev Baral +8 more
doaj +1 more source
Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus
Animal Research and One Health, EarlyView.The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary +7 more
wiley +1 more source
An Influenza Virus M2 Protein Specific Chimeric Antigen Receptor Modulates Influenza A/WSN/33 H1N1 Infection In Vivo [PDF]
, 2013 A potential target for the development of universal vaccine strategies against Influenza A is the M2 protein – a membrane protein with a highly conserved extracellular domain.
Blair, Natalie F +5 more
core +1 more source
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
Animal Research and One Health, EarlyView.A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Patent Landscape of Influenza A Virus Prophylactic Vaccines and Related Technologies [PDF]
, 2012 Executive Summary: This report focuses on patent landscape analysis of technologies related to prophylactic vaccines targeting pandemic strains of influenza.
Barton, Jeremy +5 more
core +1 more source
Pseudotypes: your flexible friends [PDF]
, 2014 Pseudotype viruses: applications and troubleshooting' (EuroSciCon 2013), a 1-day conference held at Cineworld: The O2 (London, UK) on 2 October 2013, focused on the technique of pseudotyping enveloped viruses (for a review of the technique, see [1]). The
Daly, Janet M., King, Barnabas
core +2 more sources
Wildlife Letters, EarlyView.The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie +15 more
wiley +1 more source
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Aim In this study, we aimed to provide a comprehensive analysis of real‐world implications for the therapeutic efficacy and safety of baloxavir marboxil, oseltamivir phosphate capsules and oseltamivir phosphate granules in the treatment of 160 Chinese children with influenza A. Methods This retrospective study included children aged 10–16 with
Wei Li +8 more
wiley +1 more source