Results 41 to 50 of about 18,649 (175)

Burden of Influenza in Patients Visiting Emergency Department for Treatment of Influenza Like Illness at THQ Hospital Shujabad, Pakistan [PDF]

, 2020
Background: Viral infection of the respiratory tract is a common illness syndrome in humans. Human respiratory tract is infected by large number of viruses. Self-constraining infections are caused by most of them e.g.
Chaudhry, M. (Mamoona), Kaunain, S. A. (Syed), Siftain, A. (Ali), Zaman, M. S. (Muhammad), Zulfiqar, T. (Taiba)   +4 more
core  

A bivalent live-attenuated influenza vaccine for the control and prevention of H3N8 and H3N2 canine influenza viruses [PDF]

, 2017
Canine influenza viruses (CIVs) cause a contagious respiratory disease in dogs. CIV subtypes include H3N8, which originated from the transfer of H3N8 equine influenza virus (EIV) to dogs; and the H3N2, which is an avian-origin virus adapted to infect ...
Martínez-Sobrido, Luis, Murcia, Pablo R., Nogales, Aitor, Parrish, Colin, Rodriguez, Laura   +4 more
core   +1 more source

Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans

Cell Reports
Summary: Viral pandemics and epidemics pose a significant global threat. While macaque models of viral disease are routinely used, it remains unclear how conserved antiviral responses are between macaques and humans.
Kalani Ratnasiri, Hong Zheng, Jiaying Toh, Zhiyuan Yao, Veronica Duran, Michele Donato, Mario Roederer, Megha Kamath, John-Paul M. Todd, Matthew Gagne, Kathryn E. Foulds, Joseph R. Francica, Kizzmekia S. Corbett, Daniel C. Douek, Robert A. Seder, Shirit Einav, Catherine A. Blish, Purvesh Khatri   +17 more
doaj   +1 more source

Defective interfering virus protects elderly mice from influenza [PDF]

, 2011
Background: We have identified and characterised a defective-interfering (DI) influenza A virus particles containing a highly deleted segment 1 RNA that has broad-spectrum antiviral activity.
Scott, P. D. (Paul D.), Meng, Bo, Marriott, Anthony C., Easton, A. J. (Andrew J.), Dimmock, N. J.   +4 more
core   +3 more sources

Antiviral Activity of Uridine Derivatives of 2-Deoxy Sugars against Tick-Borne Encephalitis Virus

Molecules, 2019
Tick-borne encephalitis virus (TBEV) is a causative agent of tick-borne encephalitis (TBE), one of the most important human infections involving the central nervous system.
Ewelina Krol, Ilona Wandzik, Gabriela Brzuska, Luděk Eyer, Daniel Růžek, Boguslaw Szewczyk   +5 more
doaj   +1 more source

Human infections associated with wild birds. [PDF]

, 2008
IntroductionWild birds and especially migratory species can become long-distance vectors for a wide range of microorganisms. The objective of the current paper is to summarize available literature on pathogens causing human disease that have been ...
Bauchinger, Ulf, Falagas, Matthew E, Kelesidis, Iosif, Kelesidis, Theodoros, Tsiodras, Sotirios   +4 more
core   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

ORTHOMYXO- AND PARAMYXOVIRUSES IN MARINE MAMMALS

Юг России: экология, развитие, 2018
. Aim. Marine mammals play the role of "sentries", standing guard over the health and functioning of marine ecosystems. The analysis of data reported in literature was carried out to understand and to evaluate a circulation of representatives of the ...
Marina G. Gulyaeva, Alexander Yu. Alekseev, Kirill A. Sharshov, Gayirbeg M. Abdurakhmanov, Alimurad A. Gadzhiev, Madina G. Daudova, Madina Z. Magomedova, Alexander M. Shestopalov   +7 more
doaj   +1 more source

Tick-transmitted thogotovirus gains high virulence by a single MxA escape mutation in the viral nucleoprotein.

PLoS Pathogens, 2020
Infections with emerging and re-emerging arboviruses are of increasing concern for global health. Tick-transmitted RNA viruses of the genus Thogotovirus in the Orthomyxoviridae family have considerable zoonotic potential, as indicated by the recent ...
Jonas Fuchs, Alexander Oschwald, Laura Graf, Georg Kochs   +3 more
doaj   +1 more source