Results 91 to 100 of about 176,771 (338)

Multimodal Synergistic Strategies for Diabetic Wound Healing Using Glucose Oxidase Nanocomposites: Therapeutic Mechanisms and Nanomaterial Design

open access: yesInternational Journal of Nanomedicine
Zaiwei Fan,1,* Chengzhi Liang,1,* Jiayu Zhang,2,* Yiming Li,3,* Lihua Tan,1 Hui Deng,1 Pinkai Wang,1 Jialiang Wang,1 Jiawei Kang,1 Yudan Zhu,1 Hang Fu,1 Jun Tao1 1Department of Orthopedics, The Second Affiliated Hospital ...
Fan Z   +11 more
doaj  

An Injectable BMP‐2‐Releasing Porous Hydrogel Regulating the Paracrine Effects of ADSCs Promotes Tendon‐to‐Bone Healing in Rotator Cuff Repair

open access: yesAdvanced Science, EarlyView.
This study designs an injectable porous hydrogel (HMs/MBs/ADSCs) integrating hollow microspheres for sustained BMP‐2 release to enhance adipose‐derived stem cells' paracrine effect. It accelerates tendon‐bone healing in rat rotator cuff injuries via spatiotemporal regulation: early AMPK‐mediated mitochondrial protection and late TGF‐β/Smad2/3‐driven ...
Meijuan Yuan   +11 more
wiley   +1 more source

Perineural Dexamethasone is More Efficient Than Perineural Dexmedetomidine in Prolonging Popliteal Sciatic and Saphenous Nerve Blocks: A Single-Center, Prospective, Double-Blinded, Randomized Controlled Trial

open access: yesLocal and Regional Anesthesia
Guiyu Lei,1 Lili Wu,1 Yue Yin,1 Shu Zhang,2 Guyan Wang1 1Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, People’s Republic of China; 2Center of Foot and Ankle Surgery, Beijing Tongren Hospital, Capital
Lei G, Wu L, Yin Y, Zhang S, Wang G
doaj  

Effect of a Habitual Late-Evening Physical Task on Sleep Quality in Neither-Type Soccer Players

open access: yesFrontiers in Physiology, 2018
Purpose: The aim of this study was to investigate objective and subjective sleep quality, daytime tiredness and sleepiness in response to a late-evening high intensity interval training (HIIT) session in neither-type soccer players that habitually ...
Jacopo A. Vitale   +5 more
doaj   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang   +6 more
wiley   +1 more source

Biomaterials for Adhesion in Orthopedic Applications: A Review

open access: yesEngineered Regeneration, 2020
Adhesive biomaterials, historically, have had a wide range of applications in all medical fields. With the extensive variety of biomaterials with adhesion properties, the field of orthopedics benefits from using adhesives which can provide superior ...
Younis Zaokari   +2 more
doaj  

Dual‐Biomimetic Bone Adhesive with Osteoimmunomodulatory Capabilities for Anatomical Reconstruction of Comminuted Fractures

open access: yesAdvanced Science, EarlyView.
A structurally and functionally dual bionic bone adhesive is engineered through an organic–inorganic cohesion strategy, which significantly reinforces the adhesive's bone tissue adhesion as well as osteogenic activity. In a pioneering rabbit radius comminuted fracture model, the bone adhesive exhibits exceptional capability in immobilizing bone ...
Junyao Cheng   +13 more
wiley   +1 more source

Publication characteristics of studies published in the The Spine Journal from 2005 to 2015

open access: yesOrthopedic Reviews, 2019
BACKGROUND CONTEXT: There is a growing demand for evidence-based- practices and informed clinical decision making supported by reliable, high-quality research.
Joseph Park   +4 more
doaj   +1 more source

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