Primary cultures of chick osteocytes retain functional gap junctions between osteocytes and between osteocytes and osteoblasts [PDF]
The inaccessibility of osteocytes due to their embedment in the calcified bone matrix in vivo has precluded direct demonstration that osteocytes use gap junctions as a means of intercellular communication.
Ishihara, Yoshihito+6 more
core +1 more source
Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe+4 more
wiley +1 more source
Three-dimensional analysis of mandibular landmarks, planes and shape, and the symphyseal changes associated with growth and orthodontic treatment [PDF]
OBJECTIVE: To test reliability of 3D mandibular landmarks, planes of reference and surfaces and assess their correlation to conventional 2D cephalometric measurements.
Deller, Cecilia Mercedes
core
Digital Orthopaedics: A Glimpse Into the Future in the Midst of a Pandemic. [PDF]
BackgroundThe response to COVID-19 catalyzed the adoption and integration of digital health tools into the health care delivery model for musculoskeletal patients. The change, suspension, or relaxation of Medicare and federal guidelines enabled the rapid
Ast, Michael P+9 more
core
Correlation between parodontal indexes and orthodontic retainers: prospective study in a group of 16 patients [PDF]
Purpose. Fixed retainers are used to stabilize dental elements after orthodontic treatment. Being it a permanent treatment, it is necessary to instruct patients about a constant and continuous monitoring of their periodontal conditions and a correct oral
Corsalini, M.+8 more
core +2 more sources
PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou+7 more
wiley +1 more source
I-nteract: A cyber-physical system for real-time interaction with physical and virtual objects using mixed reality technologies for additive manufacturing [PDF]
This paper presents I-nteract, a cyber-physical system that enables real-time interaction with real and virtual objects in a mixed augmented reality environment to design 3D models for additive manufacturing. The system has been developed using mixed reality technologies such as HoloLens, for augmenting visual feedback, and haptic gloves, for ...
arxiv
Accelerated Bone Healing via Electrical Stimulation
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun+4 more
wiley +1 more source
Mechanical Orthosis Mechanism to Facilitate the Extension of the Leg [PDF]
This paper presents the design of a mechanism to help people using mechanical orthoses to extend their legs easily and lock the knee joint of their orthosis. Many people living with spinal cord injury are living with paraplegia and thus need orthoses to be able to stand and walk. Mechanical orthoses are common types of orthopedic devices.
arxiv
Relationship between cervical spine and skeletal class II in subjects with and without temporomandibular disorders [PDF]
AIM. To assess changes of cranio-cervical structure and of hyoid bone position in skeletal Class II subjects with and without Temporomandibular disorders (TMD). MATERIAL AND METHODS.
DI GIACOMO, PAOLA+5 more
core +1 more source