Results 61 to 70 of about 224,709 (317)

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

open access: yesAdvanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li   +12 more
wiley   +1 more source

Visual Attention Based Cognitive Human-Robot Collaboration for Pedicle Screw Placement in Robot-Assisted Orthopedic Surgery [PDF]

open access: yes
Current orthopedic robotic systems largely focus on navigation, aiding surgeons in positioning a guiding tube but still requiring manual drilling and screw placement. The automation of this task not only demands high precision and safety due to the intricate physical interactions between the surgical tool and bone but also poses significant risks when ...
arxiv   +1 more source

Osseointegrated prostheses for rehabilitation following amputation : The pioneering Swedish model. [PDF]

open access: yes, 2017
The direct attachment of osseointegrated (OI) prostheses to the skeleton avoids the inherent problems of socket suspension. It also provides physiological weight bearing, improved range of motion in the proximal joint, as well as osseoperceptive sensory ...
Brånemark, Rickard, Li, Yan
core   +1 more source

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang   +18 more
wiley   +1 more source

Effect of a Habitual Late-Evening Physical Task on Sleep Quality in Neither-Type Soccer Players

open access: yesFrontiers in Physiology, 2018
Purpose: The aim of this study was to investigate objective and subjective sleep quality, daytime tiredness and sleepiness in response to a late-evening high intensity interval training (HIIT) session in neither-type soccer players that habitually ...
Jacopo A. Vitale   +5 more
doaj   +1 more source

Finite element analysis of porously punched prosthetic short stem virtually designed for simulative uncemented hip arthroplasty [PDF]

open access: yes, 2017
Background: There is no universal hip implant suitably fills all femoral types, whether prostheses of porous short-stem suitable for Hip Arthroplasty is to be measured scientifically.
Bai, Bo   +4 more
core   +2 more sources

Genetics‐Based Targeting Strategies for Precise Neuromodulation

open access: yesAdvanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He   +11 more
wiley   +1 more source

Methodical Approach for Determining the Length of Drill Channels in Osteosynthesis

open access: yesSensors, 2019
In order to fix a fracture in osteosynthesis, it is necessary to attach screws bicortically to the bone. The length of the screws must be selected correctly in 1-mm increments: otherwise, injury to the surrounding tissue structure or insufficient ...
Michael Sorg   +2 more
doaj   +1 more source

Composer: Visual Cohort Analysis of Patient Outcomes [PDF]

open access: yesarXiv, 2018
Objective: Visual cohort analysis utilizing electronic health record data has become an important tool in clinical assessment of patient outcomes. In this paper, we introduce Composer, a visual analysis tool for orthopedic surgeons to compare changes in physical functions of a patient cohort following various spinal procedures.
arxiv  

The clinical features of the piriformis syndrome: a systematic review [PDF]

open access: yes, 2010
Piriformis syndrome, sciatica caused by compression of the sciatic nerve by the piriformis muscle, has been described for over 70 years; yet, it remains controversial. The literature consists mainly of case series and narrative reviews. The objectives of
A Chantraine   +117 more
core   +2 more sources

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