Results 61 to 70 of about 266,380 (370)

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

Orthopedic Prosthetic Infections: Diagnosis and Orthopedic Salvage [PDF]

Seminars in Plastic Surgery, 2016
Orthopedic hardware infections are much feared and costly complications that can occur when these devices are implemented both in traumatic cases as well as in joint replacement surgery. Because these infections can lead to great morbidity, it is important to understand their pathophysiology as well as the principles behind their diagnosis and initial ...
Jesse D. Meaike, Shayan A. Izaddoost, Matthew G. Kaufman   +2 more
openaire   +3 more sources

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

The clinical features of the piriformis syndrome: a systematic review [PDF]

, 2010
Piriformis syndrome, sciatica caused by compression of the sciatic nerve by the piriformis muscle, has been described for over 70 years; yet, it remains controversial. The literature consists mainly of case series and narrative reviews. The objectives of
A Chantraine, A Hulbert, A Ku, A Miller, AG Filler, AH Freiberg, AH Freiberg, AJ Sutton, AM Lewis, B Gandhavadi, B Kumar, BSE Rich, C Steiner, CC Stegbauer, CE Dionne, CW Chang, CW Slipman, D Pokorny, D West, DA Jabs, DL Kent, DR Robinson, E Ernst, E Ernst, E Ernst, E Ernst, EC Papadopoulos, EC Yuen, EM Raney, ER Benson, EW Retzlaff, EY Lee, F Cramp, Fujian Song, G Waddell, GM Wyant, H Nakamura, HF Guyomarc’h, HI Pecina, HT Benzon, HW Park, I Colmegna, I Kosukegawa, IM Merlo, J Dalmau-Carola, J Karppinen, J Kouvalchouk, J Soga, J Young, JA Adams, JA Brown, JB Pace, JD Stewart, JJ Jankiewicz, JK Silver, JP Vandenbroucke, JS Kirschner, JWT Byrd, K Hopayian, K Indrekvam, K Konstantinou, Kevork Hopayian, KJ Stevens, KW Chong, L Jroundi, LF Solheim, LM Fishman, LM Fishman, LM Fishman, M Hanania, M Jenicek, M Pecina, M Tulder van, MC Vallejo, ME Julsrud, MR Foster, MR Foster, MW Cook, N Mayrand, NA Broadhurst, OA El Rubaidi, P Kobbe, P Limongelli, P Rossi, PM Barton, PM Bossuyt, R Dhote, RA Beatty, RD Karl Jr, Ricardo Riera, RJ Spinner, RL Tiel, RL Tiel, RP Beauchesne, RP Hallin, RR Richardson, S Bustamante, S Ozaki, S Turtas, SC Sayson, Sidha Sambandan, SJ Yoon, SM Papadopoulos, SM Papadopoulos, SS Hughes, T Banerjee, T Rodrigue, TN Bernard, TS Carey, V Rucco, VM Synek, VM Synek, WJ Mixter, WP Vandertop, WS Chen, WS Chen, WS Chen, Z Durrani   +117 more
core   +2 more sources

Oxide Bioceramic Composites in Orthopedics and Dentistry

Journal of Composites Science, 2021
Ceramic composites based on alumina and zirconia have found a wide field of application in the present century in orthopedic joint replacements, and their use in dentistry is spreading.
C. Piconi, S. Sprio
semanticscholar   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source

Sportorthopädie | Sports Orthopedics

Deutsche Zeitschrift für Sportmedizin, 2018
Optimizing precision and efficacy of measures on the individual level beyond what is achievable based on group means is the characterizing aim of personalized medicine. Sports medicine is a promising field of application for this concept and some aspects
Hecksteden A, Meyer T
doaj   +3 more sources

Rapid Aggregation of Staphylococcus aureus in Synovial Fluid Is Influenced by Synovial Fluid Concentration, Viscosity, and Fluid Dynamics, with Evidence of Polymer Bridging

mBio, 2022
Early bacterial survival in the postsurgical joint is still a mystery. Recently, synovial fluid-induced aggregation was proposed as a potential mechanism of bacterial protection upon entry into the joint. As synovial fluid is secreted back into the joint
Amelia Staats, Peter W. Burback, Andrew Schwieters, Daniel Li, Anne Sullivan, Alexander R. Horswill, Paul Stoodley   +6 more
doaj   +1 more source

Dynamics of Bone Trap-5b Level in Patients with Bone Metastases of Renal Cell Cancer at Combined Treatment [PDF]

, 2017
The objective of this study was to determine the sensitivity of tartrate-resistant acid phosphatase (Bone TRAP-5b) for early detection of bone metastases (BM) and to investigate the efficacy of bisphosphonates (BF) (zolendronic acid-ZA) in prevention of ...
Boichuk, S. (Serhiy), Diedkov, A. (Anatoliy), Kostiuk, V. (Viktor), Ostafiychuk, V. (Vasyliy)   +3 more
core   +2 more sources

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source