Human Monkeypox Outbreak Caused by Novel Virus Belonging to Congo Basin Clade, Sudan, 2005
To determine the outbreak source of monkeypox virus (MPXV) infections in Unity State, Sudan, in November 2005, we conducted a retrospective investigation. MPXV was identified in a sub-Sahelian savannah environment. Three case notification categories were
Pierre Formenty+19 more
doaj +1 more source
MHCII molecules are heterodimeric cell surface proteins composed of an α and β chain. These molecules are almost exclusively expressed on thymic epithelium and antigen presenting cells (APCs) and play a central role in the development and function of CD4
Alsharifi, Mohammed+4 more
core +1 more source
Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity [PDF]
Virus infection of mammalian cells is sensed by pattern recognition receptors and leads to an innate immune response that restricts virus replication and induces adaptive immunity.
Benfield, C T O+6 more
core +1 more source
Cowpox Virus Transmission from Pet Rats to Humans, Germany
We describe a cluster of cowpox virus (CPXV) infections in humans that occurred near Munich, Germany, around the beginning of 2009. Previously, only sporadic reports of CPXV infections in humans after direct contact with various animals had been ...
Hartmut Campe+11 more
doaj +1 more source
Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors. [PDF]
Protein kinase PKR (also known as EIF2AK2) is activated during viral infection and phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF2), leading to inhibition of translation and viral replication. We report fast evolution
Dever, Thomas E+4 more
core
Serological study of vaccinia virus reservoirs in areas with and without official reports of outbreaks in cattle and humans in São Paulo, Brazil [PDF]
Vaccinia virus (VACV), the etiological agent of an exanthematic disease, has been associated with several bovine outbreaks in Brazil since the end of the global vaccination campaign against smallpox. It was previously believed that the vaccine virus used
Acácia Ferreira Vicente+13 more
core +1 more source
mRNA Vaccine Against Mpox: A Promising Healthcare Strategy
Animal Research and One Health, Volume 3, Issue 2, Page 177-180, May 2025.
Mohammad Shah Alam+3 more
wiley +1 more source
Orthopoxvirus real-time PCR v3 [PDF]
A real-time PCR targeting the DNA-dependent RNA polymerase of Orthopoxviruses. This protocol was designed and developed at this laboratory.
Judy A Northill+2 more
openaire +1 more source
Emerging and recurring diseases in cetaceans worldwide and the role of environmental stressors. Scientific Committee Document SC/60/DW5, International Whaling Commission, June 2008, Santiago, Chile [PDF]
Emerging and recurring infectious diseases known or suspected to have the potential to significantly impact cetacean populations, and possible synergistic effects of environmental factors are reviewed.
Aguilar, A.+11 more
core
Genome of Alaskapox Virus, a Novel Orthopoxvirus Isolated from Alaska
Since the eradication of smallpox, there have been increases in poxvirus infections and the emergence of several novel poxviruses that can infect humans and domestic animals. In 2015, a novel poxvirus was isolated from a resident of Alaska.
C. Gigante+9 more
semanticscholar +1 more source