Results 151 to 160 of about 11,818 (284)

Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease

Microbiology Spectrum
Although smallpox has been eradicated, other orthopoxviruses continue to be a public health concern as exemplified by the ongoing Mpox (formerly monkeypox) global outbreak.
Rajini R. Mudhasani, Joseph W. Golden, Gregory C. Adam, Timothy J. Hartingh, Krishna P. Kota, David Ordonez, Corey R. Quackenbush, Julie P. Tran, Curtis Cline, Janice A. Williams, Xiankun Zeng, David B. Olsen, Linda A. Lieberman, Christopher Boyce, Anthony Ginnetti, J. Matthew Meinig, Rekha G. Panchal, Eric M. Mucker   +17 more
doaj   +1 more source

Isolation and partial characterization of an orthopoxvirus from a California vole(Microtus californicus) [PDF]

, 1987
David C. Regnery
openalex   +1 more source

Bovine Vaccinia: Insights into the Disease in Cattle

Viruses, 2018
Bovine vaccinia (BV), caused by Vaccinia virus (VACV), is a zoonosis characterized by exanthematous lesions in the teats of dairy cows and the hands of milkers and is an important public health issue. Severe VACV-induced lesions in the teats and udder of
Ana Carolina Diniz Matos, Izabelle Silva Rehfeld, Maria Isabel Maldonado Coelho Guedes, Zélia Inês Portela Lobato   +3 more
doaj   +1 more source

Evidence of poxvirus in dusky dolphin (Lagenorhynchus obscurus) and Burmeister's porpoise (Phocoena spinipinnis) from coastal Peru [PDF]

, 1993
In 1990, 74 dusky dolphins (Lagenorhynchus obscurus) and 10 Burmeister's porpoises (Phocoena spinipinnis) were examined for the presence of hyperpigmented marks and pinhole lesions on the skin (tattoo lesions) at the fishing terminal of Pucusana, central
Dekegel, D., Pastoret, P.-P., Reyes, J.C., Van Bressem, M.-F., Van Waerebeek, K.   +4 more
core  

CRISPR/Cas9—Advancing Orthopoxvirus Genome Editing for Vaccine and Vector Development

Viruses, 2018
The clustered regularly interspaced short palindromic repeat (CRISPR)/associated protein 9 (Cas9) technology is revolutionizing genome editing approaches.
Arinze Okoli, Malachy I. Okeke, Morten Tryland, Ugo Moens   +3 more
doaj   +1 more source

Efficacy of three key antiviral drugs used to treat orthopoxvirus infections: a systematic review

Global Biosecurity, 2019
Background: In a global political climate increasingly concerned about terrorism, bioterrorism agents such as smallpox would undoubtedly be catastrophic.
Joyce Yu, S. M. Raj
semanticscholar   +1 more source

Characterization of ATI, TK and IFN-alpha/betaR genes in the genome of the BeAn 58058 virus, a naturally attenuated wild Orthopoxvirus. [PDF]

, 2001
João T. Marques, Giliane de Souza Trindade, Flávio Guimarães da Fonseca, João Rodrigues dos Santos, Cláudio Antônio Bonjardim, Paulo César Peregrino Ferreira, Erna Geessien Kroon   +6 more
openalex   +1 more source

Identification of the Orthopoxvirus p4c Gene, Which Encodes a Structural Protein That Directs Intracellular Mature Virus Particles into A-Type Inclusions [PDF]

, 2002
Terry A. McKelvey, Stanley C. Andrews, Sara Miller, Caroline A. Ray, David J. Pickup   +4 more
openalex   +1 more source

MHC Class II–Alpha Chain Knockout Mice Support Increased Viral Replication That Is Independent of Their Lack of MHC Class II Cell Surface Expression and Associated Immune Function Deficiencies

, 2015
MHCII molecules are heterodimeric cell surface proteins composed of an α and β chain. These molecules are almost exclusively expressed on thymic epithelium and antigen presenting cells (APCs) and play a central role in the development and function of CD4
Alsharifi, Mohammed, Bettadapura, Jayaram, Koskinen, Aulikki, Müllbacher, Arno, Wijesundara, Danushka K.   +4 more
core   +1 more source

POTION: um software paralelizado para a detecção de grupos de genes homólogos sob evidência de seleção positiva em escala genômica. [PDF]

, 2020
O presente trabalho descreve o desenvolvimento do software POTION (POsitive selecTION) para a busca por grupos de genes homólogos sob evidência de seleção ...
HONGO, J. A., LOBO, F. P.
core