Results 111 to 120 of about 1,311,722 (333)

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor

Molecular Systems Biology, 2009
Although the ERK pathway has a central role in the response of cells to growth factors, its regulatory structure and dynamics are incompletely understood. To investigate ERK activation in real time, we expressed an ERK–GFP fusion protein in human mammary
Harish Shankaran, Danielle L Ippolito, William B Chrisler, Haluk Resat, Nikki Bollinger, Lee K Opresko, H Steven Wiley   +6 more
doaj   +1 more source

Crosslinkage of B lymphocyte surface immunoglobulin by anti-Ig or antigen induces prolonged oscillation of intracellular ionized calcium

Journal of Experimental Medicine, 1987
Our results indicate that B lymphocytes stimulated with anti-Ig or antigen exhibit repetitive [Ca2+]i transients which persist for hours. The magnitude of these transients favors an important and ongoing role for [Ca2+]i elevation in antigen driven B ...
BY W. A. Wilson, David Greenblatt, M. Poenie, F. Finkelman, R. Tsien   +4 more
semanticscholar   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Modulation of Circadian Rhythm of DNA Synthesis in Tumor Cells by Inhibiting Platelet-Derived Growth Factor Signaling

Journal of Pharmacological Sciences, 2008
Circadian synchronization of cell proliferation is observed not only in normal healthy tissues but also in malignant solid tumors. However, the proliferation rhythm of tumor cells is often different from that of normal cells.
Hiroo Nakagawa, Satoru Koyanagi, Yukako Kuramoto, Akiko Yoshizumi, Naoya Matsunaga, Hiroshi Shimeno, Shinji Soeda, Shigehiro Ohdo   +7 more
doaj   +1 more source

Stochastic Binary Modeling of Cells in Continuous Time as an Alternative to Biochemical Reaction Equations

, 2011
We have developed a coarse-grained formulation for modeling the dynamic behavior of cells quantitatively, based on stochasticity and heterogeneity, rather than on biochemical reactions.
Akira, Shizuo, Kumagai, Yutaro, Standley, Daron M, Teraguchi, Shunsuke, Vandenbon, Alexis   +4 more
core   +1 more source

Amplification of Ca2+ Signaling by Diacylglycerol-mediated Inositol 1,4,5-Trisphosphate Production*

Journal of Biological Chemistry, 2005
Stimulation of various cell surface receptors leads to the production of inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) through phospholipase C (PLC) activation, and the IP3 and DAG in turn trigger Ca2+ release through IP3 receptors and ...
C. Hisatsune, Kyoko Nakamura, Y. Kuroda, Takeshi Nakamura, K. Mikoshiba   +4 more
semanticscholar   +1 more source

CO2 Reduction on Copper‐Nitrogen‐Doped Carbon Catalysts Tuned by Pulsed Potential Electrolysis: Effect of Pulse Potential

Advanced Functional Materials, EarlyView.
This study demonstrates that pulsed potential electrolysis significantly improves CO2 reduction performance on copper‐nitrogen doped carbon electrodes. The formation of cationic copper sites and metallic clusters as a function of applied intermittent potential leads to notable selectivity changes compared to potentiostatic reduction.
Dorottya Hursán, Janis Timoshenko, Andrea Martini, Hyo Sang Jeon, Eduardo Ortega, Martina Rüscher, Arno Bergmann, Aram Yoon, Uta Hejral, Antonia Herzog, Clara Rettenmaier, Felix T. Haase, Philipp Grosse, Beatriz Roldan Cuenya   +13 more
wiley   +1 more source

Transparent Inorganic–Organic Bilayer Neural Electrode Array and Integration to Miniscope System for In Vivo Calcium Imaging and Electrophysiology

Advanced Functional Materials, EarlyView.
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han, Kevin Cheng, Swathy Sampath Kumar, Anil Bollimunta, Elizabeth E. Torr, Juhwan Kim, Kyoungmin Kim, Hyungjun Choi, Seongkwon Hwang, Sarah Brodnick, David Cheng, Lindsay Gray, Yei Hwan Jung, William L. Murphy, Aaron J. Suminski, Jonathan J. Nassi, Justin C. Williams, Dong‐Wook Park   +17 more
wiley   +1 more source

Phase responses of oscillating components in a signaling pathway

Frontiers in Physiology, 2013
Signal transduction pathways control various events in mammalian cells such as growth, proliferation,differentiation, apoptosis, or migration in response to environmental stimuli.Because of their importance, the activity of signaling pathways is ...
Masaki eNomura, Mariko eOkada-Hatakeyama
doaj   +1 more source