Results 151 to 160 of about 1,311,722 (333)

mTORC1 activity oscillates throughout the cell cycle, promoting mitotic entry and differentially influencing autophagy induction

open access: yesCell Reports
Summary: Mechanistic Target of Rapamycin Complex 1 (mTORC1) is a master metabolic regulator that is active in nearly all proliferating eukaryotic cells; however, it is unclear whether mTORC1 activity changes throughout the cell cycle. We find that mTORC1
Jay N. Joshi   +6 more
doaj   +1 more source

Viscoelasticity‐Induced Controllable Periodic Meso‐Textures of Liquid Crystal Polymers in Additive Manufacturing

open access: yesAdvanced Functional Materials, EarlyView.
Viscoelasticity‐driven instabilities are harnessed to create tunable, periodic textures in 3D‐printed liquid crystalline polymers. This study illustrates how processing parameters control these spontaneous meso‐scale patterns. These unique structural architectures unlock new possibilities for functional devices, ranging from photonic components to ...
Miaomiao Zou   +17 more
wiley   +1 more source

In Materia Shaping of Randomness with a Standard Complementary Metal‐Oxide‐Semiconductor Transistor for Task‐Adaptive Entropy Generation

open access: yesAdvanced Functional Materials, EarlyView.
This study establishes a materials‐driven framework for entropy generation within standard CMOS technology. By electrically rebalancing gate‐oxide traps and Si‐channel defects in foundry‐fabricated FDSOI transistors, the work realizes in‐materia control of temporal correlation – achieving task adaptive entropy optimization for reinforcement learning ...
Been Kwak   +14 more
wiley   +1 more source

Origins of Ultrasensitivity and Complex Signaling Dynamics of Cellular Hydrogen Peroxide and Peroxiredoxin

open access: yesAntioxidants
Hydrogen peroxide (H2O2) plays a crucial role in cell signaling in response to physiological and environmental perturbations. H2O2 can oxidize typical 2-Cys peroxiredoxin (PRX) first into a sulfenic acid, which resolves into a disulfide that can be ...
Shengnan Liu, Jingbo Pi, Qiang Zhang
doaj   +1 more source

Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: Role of calcineurin/NFAT as Ca2+ signal integrators

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2008
M. Colella   +5 more
semanticscholar   +1 more source

Atomic‐Level Dual‐Cation Engineering Enables High‐Performance Na4VMn(PO4)3 Cathodes for Sodium‐Ion Batteries

open access: yesAdvanced Functional Materials, EarlyView.
Dual‐cation site engineering unlocks stable and fast sodium storage in Na4VMn(PO4)3 cathodes. Li+ at Na2 suppresses Jahn‐Teller distortion, while K+ at Na1 expands ion channels, enabling synchronized V/Mn redox and quasi‐single‐phase kinetics. This atomic‐level strategy achieves ultralong cycling stability, high‐rate capability, and full cell viability
Jiaze Sun   +8 more
wiley   +1 more source

Role of Histidine‐Containing Peptoids in Accelerating the Kinetics of Calcite Growth

open access: yesAdvanced Functional Materials, EarlyView.
Amphiphilic histidine‐containing peptoids mimic carbonic anhydrase (CA) to accelerate calcite step growth. In the presence of Zn2+, they promote the deprotonation of HCO3−, the desolvation of Ca2+, and the reorganization of interfacial hydration layers, thereby reducing the activation barrier for calcite growth.
Mingyi Zhang   +5 more
wiley   +1 more source

The role of periodic signals in the morphogenesis of Dictyostelium discoideum [PDF]

open access: yes, 1993
Rensing, Ludger   +2 more
core   +1 more source

Visualization of Notch signaling oscillation in cells and tissues.

open access: yesVisualization of Notch signaling oscillation in cells and tissues.
The Notch signaling effectors Hes1 and Hes7 exhibit oscillatory expression with a period of about 2-3 h during embryogenesis. Hes1 oscillation is important for proliferation and differentiation of neural stem cells, whereas Hes7 oscillation regulates periodic formation of somites.
openaire  

Effects of Osmolarity on the Spontaneous Calcium Signaling of In Situ Juvenile and Adult Articular Chondrocytes

open access: yesAnnals of Biomedical Engineering, 2016
Yilu Zhou   +6 more
semanticscholar   +1 more source

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