Results 161 to 170 of about 1,506,122 (305)

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Diverse Effects of Various Toll-Like Receptor 2 Ligands on Neuronal Activity and Cell Death. [PDF]

Cell Mol Neurobiol
Sato F, Hachimura S.
europepmc   +1 more source

Tmem64 modulates calcium signaling during RANKL-mediated osteoclast differentiation.

Cell Metabolism, 2013
Hyunsook Kim, Taesoo Kim, Byung-chul Jeong, Il-Taeg Cho, Daehee Han, N. Takegahara, Takako Negishi-Koga, H. Takayanagi, Jae Hee Lee, J. Sul, V. Prasad, Seoung‐Hoon Lee, Yongwon Choi   +12 more
semanticscholar   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Downregulation of RORα by alcohol promotes TGFβ and α-SMA expression in mouse lung fibroblasts. [PDF]

Front Med (Lausanne)
Fan X, Tao H, Kang BY, Diaz N, Baba K, Tosini G, Guo J, Yeligar SM, Sueblinvong V.   +8 more
europepmc   +1 more source

Egg-to-embryo transition is driven by differential responses to Ca(2+) oscillation number.

Developmental Biology, 2002
T. Ducibella, D. Huneau, E. Angelichio, Zhe Xu, R. Schultz, G. Kopf, R. Fissore, S. Madoux, J. Ozil   +8 more
semanticscholar   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

Advanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao, Ao Zheng, Zhengyan Zhao, Qilin Li, Tianhao Wan, Tanjun Deng, Ying Zhang, Lingyan Cao, Lan Wu   +8 more
wiley   +1 more source

Entrainment of breast (cancer) epithelial cells detects distinct circadian oscillation patterns for clock and hormone receptor genes

Cell Cycle, 2012
Stefano Rossetti, Joseph Esposito, F. Corlazzoli, Alex Gregorski, N. Sacchi   +4 more
semanticscholar   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source