Results 161 to 170 of about 50,029 (292)

Programmed Aggregation of Lipidated Nitrobenzoselenadiazole as a Photo‐Activatable Pyroptosis Inducer

Advanced Healthcare Materials, EarlyView.
This study presents alkylated nitrobenzoselenadiazole (NBSD) photosensitizers that self‐assemble into programmable aggregates, enabling photo‐triggered pyroptosis and enhanced ROS generation. The lead compound, NBSD‐NOc, exhibits superior photodynamic activity, high cellular uptake, and implantable gel compatibility with pH‐responsive release.
Jong Min An, Hyunyoung Choi, Hyo In Kim, Do‐Yeon Kim, Jahyun Kim, Jinbong Park, Junyang Jung, Na Young Jeong, Dokyoung Kim   +8 more
wiley   +1 more source

Photocrosslinkable Kidney Decellularized Extracellular Matrix‐Based Bioink for 3D Bioprinting

Advanced Healthcare Materials, EarlyView.
A photocrosslinkable bioink is developed from methacrylated decellularized porcine kidney extracellular matrix to create kidney‐specific 3D constructs. This bioink supports high cell viability, promotes multicellular spheroid formation, and enables stable multilayer bioprinting with tunable mechanical properties, providing a versatile platform for ...
Jaemyung Shin, Nima Tabatabaei Rezaei, Subin Choi, Zhangkang Li, Deok‐Ho Kim, Keekyoung Kim   +5 more
wiley   +1 more source

Phase separation of a PKA type I regulatory subunit regulates β-cell function through cAMP compartmentalization. [PDF]

PLoS Biol
Lee HN, Hardy JC, Pool EH, Zhang JF, Kim SH, Buhl WF, Bruystens JGH, Mehta S, Taylor SS, Zhang J.   +9 more
europepmc   +1 more source

Functionalized Reduced Graphene Oxide‐Based Nanocomposite Hydrogels for Enhanced Osteogenesis in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Charge‐opposed reduced graphene oxide fillers are co‐integrated into biopolymeric nanocomposite scaffolds, synergistically enhance osteogenesis. Multiscale characterization reveals how surface chemistry and porosity dictate ectopic mineral architecture.
George Mihail Vlăsceanu, Cătălina Ionela Zamfir, Cornel Baltă, Hildegard Herman, Alina Ciceu, Maria Alexandra Duma, Mariana Ioniță, Roxana‐Cristina Popescu, Anca Hermenean   +8 more
wiley   +1 more source

Effects of taurine, brimonidine and betaxolol on oscillation modulation and stimulation efficiency in degenerated rd10 mouse retinas. [PDF]

Sci Rep
Schaffrath K, Ingensiep C, Müller F, Walter P, Johnen S.   +4 more
europepmc   +1 more source

Mechanical Reinforced and Self‐healing Hydrogels: Bioprinted Biomimetic Methacrylated Collagen Peptide‐Xanthan Gum Constructs for Ligament Regeneration

Advanced Healthcare Materials, EarlyView.
Readily UV‐curing and self‐healing methacrylated collagen peptide (COPMA) hydrogels are developed with tunable mechanical properties. As the interpenetrating network between COPMA and xanthan gum (XG), COPMA‐XG bioinks show improved mechanical properties, printability, and stability, compared to COPMA or XG.
Hongjuan Weng, Monize Caiado Decarli, Lei He, Wen Chen, Sabine van Rijt, Katrien V. Bernaerts, Lorenzo Moroni   +6 more
wiley   +1 more source

mTORC1 activity oscillates throughout the cell cycle, promoting mitotic entry and differentially influencing autophagy induction

Cell Reports
Summary: Mechanistic Target of Rapamycin Complex 1 (mTORC1) is a master metabolic regulator that is active in nearly all proliferating eukaryotic cells; however, it is unclear whether mTORC1 activity changes throughout the cell cycle. We find that mTORC1
Jay N. Joshi, Ariel D. Lerner, Frank Scallo, Alexandra N. Grumet, Paul Matteson, James H. Millonig, Alexander J. Valvezan   +6 more
doaj  

Ligand-Independent Spontaneous Activation of Purinergic P2Y₆ Receptor Under Cell Culture Soft Substrate. [PDF]

Cells
Nishimura A, Nishiyama K, Ito T, Mi X, Kato Y, Inoue A, Aoki J, Nishida M.   +7 more
europepmc   +1 more source

Modelling the effects of Notch signalling on the synchrony of neighbouring cell oscillations.

, 2015
P. Jenkins Robert, Anja Hanisch, Soza-Ried Cristian, Sahai Erik, Lewis Julian   +4 more
openalex   +1 more source

Central role of IP3R2-mediated Ca2+ oscillation in self-renewal of liver cancer stem cells elucidated by high-signal ER sensor [PDF]

, 2019
Cuiwei Sun, Bo Shui, Wei Zhao, Hui Liu, Wenwen Li, Jane C. Lee, Robert Doran, Frank K. Lee, Tao Sun, Qing Sunny Shen, Xianhua Wang, Shaun Reining, Michael I. Kotlikoff, Zhiqian Zhang, Heping Cheng   +14 more
openalex   +1 more source