Discovery of a New Phase in Thin Flakes of KV3Sb5 under Pressure
The discovery of an unexpected new phase is reported in thin flake of KV3Sb5 under pressure. The new phase, alongside the CDW and superconducting phases, reveals an intriguing interplay between various novel phases in the kagome system. These findings suggest that this phase is related to nematicity, showcasing the kagome system's potential for ...
Zheyu Wang+15 more
wiley +1 more source
An Arabidopsis Cell Culture With Weak Circadian Rhythms Under Constant Light Compared With Constant Dark Can Be Rescued by ELF3. [PDF]
Laosuntisuk K, Desai JS, Doherty CJ.
europepmc +1 more source
During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu+13 more
wiley +1 more source
Modulation of Ca2+ oscillation following ischemia and nicotinic acetylcholine receptors in primary cortical neurons by high-throughput analysis. [PDF]
Sasaki T+8 more
europepmc +1 more source
Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong+17 more
wiley +1 more source
Modeling Innate Immunity Causing Chronic Inflammation and Tissue Damage. [PDF]
Matsuo K, Iwasa Y.
europepmc +1 more source
High‐Performance Polymer‐derived Ceramics in LCD 3D Printing
This study highlights the potential of silicon oxycarbide‐based formulations for producing polymer‐derived ceramics with superior properties via LCD 3D printing. VMM‐based ceramics demonstrate a remarkable 50‐fold increase in compressive strength (up to 17 MPa) compared to SPR‐684, along with exceptional high‐temperature survivability (up to 1500 °C ...
H. Yazdani Sarvestani+6 more
wiley +1 more source
Excitable Ras dynamics-based screens reveal RasGEFX is required for macropinocytosis and random cell migration. [PDF]
Iwamoto K, Matsuoka S, Ueda M.
europepmc +1 more source
This research article introduces a novel CMOS neural probe with 1024 channels distributed across eight shanks. The SiNAPS probe allows for the simultaneous recording of both local field potentials and action potentials in large brain areas. The probe's design allows for detailed mapping and linking neural dynamics and population unit activity, as ...
Gian Nicola Angotzi+13 more
wiley +1 more source
Urolithin A Modulates PER2 Degradation via SIRT1 and Enhances the Amplitude of Circadian Clocks in Human Senescent Cells. [PDF]
Kuatov R+11 more
europepmc +1 more source