Results 291 to 300 of about 1,311,722 (333)

Intercellular signaling in glial cells: Calcium waves and oscillations in response to mechanical stimulation and glutamate

Neuron, 1991
Intercellular Ca2+ signaling in primary cultures of glial cells was investigated with digital fluorescence video imaging. Mechanical stimulation of a single cell induced a wave of increased [Ca2+]i that was communicated to surrounding cells. This was followed by asynchronous Ca2+ oscillations in some cells.
A C, Charles, J E, Merrill, E R, Dirksen, M J, Sanderson   +3 more
openaire   +2 more sources

Role of mitochondria in Ca2+ oscillations and shape of Ca2+ signals in pancreatic acinar cells

Biochemical Pharmacology, 2002
We studied the role of mitochondria in Ca(2+) signals in fura-2 loaded exocrine pancreatic acinar cells. Mitochondrial depolarization in response to carbonylcyanide-p-tryfluoromethoxyphenyl hydrazone or rotenone (assessed by confocal microscopy using rhodamine-123) induced a partial but statistically significant reduction in the decay of Ca(2+) signals
C, Camello-Almaraz, G M, Salido, J A, Pariente, P J, Camello   +3 more
openaire   +2 more sources

Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress

Cell Stem Cell
Stem cells are known for their resilience and enhanced activity post-stress. The mammary gland undergoes frequent remodeling and is subjected to recurring stress during the estrus cycle, but it remains unclear how mammary stem cells (MaSCs) respond to the stress and contribute to regeneration.
Liu, Chunye, Xu, Yishu, Yang, Guowei, Tao, Yu, Chang, Jiali, Wang, Shihui, Cheung, Hiu Tung, Chen, Jianfeng, Zeng, Yi Arial   +8 more
openaire   +3 more sources

Modelling of simple and complex calcium oscillations

European Journal of Biochemistry, 2002
This review provides a comparative overview of recent developments in the modelling of cellular calcium oscillations. A large variety of mathematical models have been developed for this wide‐spread phenomenon in intra‐ and intercellular signalling. From these, a general model is extracted that involves six types of concentration variables: inositol 1,4,
Stefan, Schuster, Marko, Marhl, Thomas, Höfer   +2 more
openaire   +2 more sources

Oscillating two-dimensional Ca²⁺ waves in cell networks with bidirectional paracrine signaling

Waves in Random and Complex Media, 2019
Nonlinear excitations of Ca2+ waves are investigated in a two-dimensional cell network with bidirectional paracrine signaling, both in the longitudinal and transversal directions.
C. B. Tabi, A. S. Etémé, A. Mohamadou, T. C. Kofané   +3 more
openaire   +1 more source

Olfactory Nerve Stimulation-Evoked mGluR1 Slow Potentials, Oscillations, and Calcium Signaling in Mouse Olfactory Bulb Mitral Cells

Journal of Neurophysiology, 2006
Fast synaptic transmission between olfactory receptor neurons and mitral cells (MCs) is mediated through AMPA and NMDA ionotropic glutamate receptors. MCs also express high levels of metabotropic glutamate receptor 1 (mGluR1) whose functional significance is less understood.
Q, Yuan, T, Knöpfel
openaire   +2 more sources

Regulation of Cell Division Cycles by Circadian Oscillators: Signal Transduction Between Clocks

1997
An important consideration for maximizing the results of radio- and chemotherapy of mammalian cancers is that of host tolerance. It is unfortunate that in most of the earlier cancer work there is little mention of the role of rhythmic variations (particularly circadian periodicities) in the susceptibility of the whole organism to the toxicity of the ...
openaire   +1 more source

Su2021 UTP Evokes CA2+ Oscillations in Human Enterochromaffin Cells via Multiple Intracellular Signaling and Ionic Mechanisms

Gastroenterology, 2014
Results: In full-thickness human ileum, anti-CdtB was specific for ICC and ganglia, based on colocalization of anti-CdtB with anti-c-kit, PGP 9.5 and S-100 (see figure). Thus antiCdtB appeared to interact with a human protein on ICCs and ganglia. Based on immunoprecipitation, a protein band was identified at 117kDa. Using mass spectroscopy this protein
Andromeda Linan Rico, Fernando Ochoa-Cortes, Mazin A. Alhaj, Josh Enneking, Emily Bitticker, Bradley J. Needleman, Alan Harzman, Iveta Grants, Fievos L. Christofi   +8 more
openaire   +1 more source

Oscillating flow promotes inflammation through the TLR2–TAK1–IKK2 signalling pathway in human umbilical vein endothelial cell (HUVECs)

Life Sciences, 2019
Oscillatory shear stress (OSS) occurs in areas where atherosclerosis is prevalent. Toll-like receptor 2 (TLR2) has been associated with mechanical-stress-mediated activation of signalling pathways that may lead to inflammation, apoptosis, and atherosclerosis.
Feng, Wang, Zhimei, Wang, Jiangqin, Pu, Xiangrong, Xie, Xiaofei, Gao, Yue, Gu, Shaoliang, Chen, Junjie, Zhang   +7 more
openaire   +2 more sources

Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression

Science, 2004
D. E. Nelson, Adaoha Elizabeth Ihekwaba, M. Elliott, James R. Johnson, C. A. Gibney, B. E. Foreman, G. Nelson, V. Sée, C. Horton, D. Spiller, S. Edwards, H. McDowell, J. Unitt, E. Sullivan, R. Grimley, N. Benson, D. Broomhead, D. Kell, M. White   +18 more
semanticscholar   +1 more source