Results 151 to 160 of about 24,935 (185)
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Drugs, 1999
Oseltamivir is the oral prodrug of GS4071, a selective inhibitor of influenza A and B viral neuraminidase. After absorption from the gastrointestinal tract oseltamivir is efficiently converted to GS4071, which is maintained at high and sustained concentrations in plasma. Based on studies in rats and ferrets, GS4071 appears to be effectively distributed
A, Bardsley-Elliot, S, Noble
openaire +3 more sources
Oseltamivir is the oral prodrug of GS4071, a selective inhibitor of influenza A and B viral neuraminidase. After absorption from the gastrointestinal tract oseltamivir is efficiently converted to GS4071, which is maintained at high and sustained concentrations in plasma. Based on studies in rats and ferrets, GS4071 appears to be effectively distributed
A, Bardsley-Elliot, S, Noble
openaire +3 more sources
Progressive emergence of an oseltamivir‐resistant A(H3N2) virus over two courses of oseltamivir treatment in an immunocompromised paediatric patient [PDF]
Influenza and Other Respiratory Viruses, 2013 A minor viral population of oseltamivir-resistant A(H3N2) viruses (E119V neuraminidase mutation) was selected and maintained in a continually infected immunocompromised child following initial oseltamivir treatment.
Aeron Hurt, Anne Kelso, Ian Barr
exaly +2 more sources
Population Pharmacokinetics of Oseltamivir When Coadministered With Probenecid
Journal of Clinical Pharmacology, 2008 Oseltamivir is a potent, selective, oral neuraminidase inhibitor for the treatment and prophylaxis of influenza. Plasma concentrations of the active metabolite, oseltamivir carboxylate, are increased in the presence of probenecid, suggesting that the ...
Rayner, Craig R. +4 more
exaly +2 more sources